Characterization of individual nanoparticles used in photothermal therapy via wide-field photothermal imaging

Nanoparticles (NPs) play a critical role across diverse fields, necessitating precise characterization methods. This study presents a streamlined wide-field photothermal microscopy (PM) system capable of photothermal transmittance imaging. Utilizing a conventional microscope integrated with two CCD cameras, a probe beam, and a pump laser, the system enables high-sensitivity detection of individual NPs without complex optical alignment. Notably, photothermal transmittance imaging demonstrates superior signal-to-noise ratios (SNR), especially for transparent samples, highlighting the system's potential for advanced NP characterization in photothermal therapy applications.

• Publication year

  2025

• Venue

  NanoScience + Engineering

• Publication date

  2025-09-16

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1117/12.3063738
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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