The hypothalamic "glucostat'': CRF neurons decode energy signals.

Ibukun Akinrinade,J. Bains

Published 2025 in Neuron

ABSTRACT

Food deprivation shifts the body's metabolic priority toward glucose utilization as a primary fuel source. A study by Kim et al.1 published in this issue of Neuron identifies a distinct population of neurons in the brain as essential for detecting this metabolic state and orchestrating adaptive responses.

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