Abrus precatorius agglutinin-derived peptides induce ROS-dependent mitochondrial apoptosis through JNK and Akt/P38/P53 pathways in HeLa cells.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Chemico-Biological Interactions

• Publication date

  2014-10-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.cbi.2014.08.017PMID 25305377
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biochemical analysis and antitumour effect of Abrus precatorius agglutinin derived peptides in Ehrlich's ascites and B16 melanoma mice tumour model.

  2014cited by this paper
• BM-1197: A Novel and Specific Bcl-2/Bcl-xL Inhibitor Inducing Complete and Long-Lasting Tumor Regression In Vivo

  2014cited by this paper
• Role of PI3K/Akt/mTOR and MEK/ERK pathway in Concanavalin A induced autophagy in HeLa cells.

  2014cited by this paper
• Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

  2013cited by this paper
• Starvation-induced autophagy is regulated by mitochondrial reactive oxygen species leading to AMPK activation.

  2013cited by this paper
• Olaquindox-induced apoptosis is suppressed through p38 MAPK and ROS-mediated JNK pathways in HepG2 cells

  2013cited by this paper
• Piperlongumine induces autophagy by targeting p38 signaling

  2013cited by this paper
• Effect of enzyme-assisted extract of Sargassum coreanum on induction of apoptosis in HL-60 tumor cells

  2012cited by this paper
• A peptide fraction from germinated soybean protein down-regulates PTTG1 and TOP2A mRNA expression, inducing apoptosis in cervical cancer cells.

  2012cited by this paper
• The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: similarities and distinct actions from soy isoflavone genistein

  2012cited by this paper
• Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

  2012cited by this paper
• Antihyperlipidemic and Antitumor Effects of Chickpea Albumin Hydrolysate

  2012cited by this paper
• Plant lectins: targeting programmed cell death pathways as antitumor agents.

  2011cited by this paper
• Activation of RAW 264.7 cells by Astraeus hygrometricus‐derived heteroglucan through MAP kinase pathway

  2011cited by this paper
• Crystal Structure of an Integron Gene Cassette-Associated Protein from Vibrio cholerae Identifies a Cationic Drug-Binding Module

  2011cited by this paper
• Resveratrol Suppresses Constitutive Activation of AKT via Generation of ROS and Induces Apoptosis in Diffuse Large B Cell Lymphoma Cell Lines

  2011cited by this paper
• Mitochondrial ROS generation for regulation of autophagic pathways in cancer.

  2011cited by this paper
• ROS-mediated autophagy was involved in cancer cell death induced by novel copper(II) complex.

  2010cited by this paper
• Plant lectins: potential antineoplastic drugs from bench to clinic.

  2010cited by this paper
• Effect of rapeseed peptide on DNA damage and apoptosis in Hela cells.

  2010cited by this paper
• Assessment of Apoptosis by Immunohistochemistry to Active Caspase-3, Active Caspase-7, or Cleaved PARP in Monolayer Cells and Spheroid and Subcutaneous Xenografts of Human Carcinoma

  2009cited by this paper
• Human colon and liver cancer cell proliferation inhibition by peptide hydrolysates derived from heat-stabilized defatted rice bran.

  2008cited by this paper
• Bioactive peptides and proteins from foods: indication for health effects

  2008cited by this paper
• Induction of mitochondria-dependent apoptosis by Abrus agglutinin derived peptides in human cervical cancer cell.

  2008cited by this paper
• Antitumor and proapoptotic effect of Abrus agglutinin derived peptide in Dalton's lymphoma tumor model.

  2008cited by this paper
• p38 MAP-kinases pathway regulation, function and role in human diseases.

  2007cited by this paper
• A radical role for p38 MAPK in tumor initiation.

  2007cited by this paper
• Induction of Apoptosis in Leukemic Cells by Homovanillic Acid Derivative, Capsaicin, through Oxidative Stress

  2004cited by this paper
• Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome and caspase pathway.

  2004cited by this paper
• Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process

  2004cited by this paper
• The role of glutathione-S-transferase in anti-cancer drug resistance

  2003cited by this paper
• Reactive oxygen species in oncogenic transformation.

  2003cited by this paper
• The mitochondrial membrane potential (Δψm) in apoptosis; an update

  2003cited by this paper
• Hepatitis B Virus X Protein Induces Cell Death by Causing Loss of Mitochondrial Membrane Potential*

  2003cited by this paper
• One-pot labeling and purification of peptides and proteins with fluorescein maleimide

  2003cited by this paper
• AplidinTM Induces Apoptosis in Human Cancer Cells via Glutathione Depletion and Sustained Activation of the Epidermal Growth Factor Receptor, Src, JNK, and p38 MAPK*

  2003cited by this paper
• The mitochondrial membrane potential (deltapsi(m)) in apoptosis; an update.

  2003cited by this paper
• Redox stress regulates cell proliferation and apoptosis of human hepatoma through Akt protein phosphorylation

  2003cited by this paper
• Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

  2002cited by this paper
• Novel indolo[2,1-b]quinazoline analogues as cytostatic agents: synthesis, biological evaluation and structure-activity relationship.

  2002cited by this paper
• AP-1 in cell proliferation and survival

  2001cited by this paper
• Bcl-xL Prevents the Initial Decrease in Mitochondrial Membrane Potential and Subsequent Reactive Oxygen Species Production during Tumor Necrosis Factor Alpha-Induced Apoptosis

  2000cited by this paper
• The hollow fiber assay: continued characterization with novel approaches.

  2000cited by this paper
• Changes in mitochondrial membrane potential during staurosporine‐induced apoptosis in Jurkat cells

  2000cited by this paper
• Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

  1995cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper
• DISTRIBUTION OF PEPTIDE-CONTAINING ENDOCRINE CELLS AND NEURONS IN THE GASTROINTESTINAL TRACT OF THE DOG: IMMUNOHISTOCHEMICAL STUDIES USING ANTISERA TO SOMATOSTATIN, SUBSTANCE P, VASOACTIVE INTESTINAL POLYPEPTIDE, MET-ENKEPHALIN, AND NEUROTENSIN

  1983cited by this paper

• Sphaerindicin: A Novel Anticancer Compound From Hydroethanoli c Extract of Sphaeranthus Indicus Against Lung Adenocarcinoma

  2025cites this paper
• The Traditional Uses, Nutrition, Phytochemistry, and Pharmacology of the Medicinal Abrus Species: A Comprehensive Review

  2025cites this paper
• Recombinant Microneme Proteins MIC1 and MIC4 from Toxoplasma gondii Cause Cytotoxic Effects in the Human Jurkat T-Lymphocyte Cell Line

  2025cites this paper
• Targeting the gut-skin axis by food-derived active peptides ameliorates skin photoaging: a comprehensive review.

  2024cites this paper
• Phytoconstituents and ethnopharmacological activities of Abrus precatorius L. (Fabaceae): a review

  2022cites this paper
• METABOLITES OF ABRUS PRECATORIUS TARGETING MULTIPLE ONCOGENIC AND ONCO-SUPPRESSIVE SIGNALING FOR CANCER PREVENTION AND INTERVENTION

  2022cites this paper
• The traditional uses, phytochemistry and pharmacology of Abrus precatorius L.: A comprehensive review.

  2022cites this paper
• Reactive oxygen nano-generators for cancer therapy

  2022cites this paper
• Liposoluble portion of the red alga Pyropia yezoensis protects alcohol induced liver injury in mice

  2021influential citation
• Activation of reactive oxygen species‐mediated mitogen‐activated protein kinases pathway regulates both extrinsic and intrinsic apoptosis induced by arctigenin in Hep G2

  2020cites this paper
• p73 induction by Abrus agglutinin facilitates Snail ubiquitination to inhibit epithelial to mesenchymal transition in oral cancer.

  2019cites this paper
• New naphthalene derivatives induce human lung cancer A549 cell apoptosis via ROS-mediated MAPKs, Akt, and STAT3 signaling pathways.

  2019cites this paper
• PUMA dependent mitophagy by Abrus agglutinin contributes to apoptosis through ceramide generation.

  2018cites this paper
• Non-apoptotic cell death in malignant tumor cells and natural compounds.

  2018cites this paper
• SYK protects cardiocytes against anoxia and hypoglycemia‐induced injury in ischemic heart failure

  2017cites this paper
• Plant Lectins Targeting O-Glycans at the Cell Surface as Tools for Cancer Diagnosis, Prognosis and Therapy

  2017cites this paper
• Survivin protects fused cancer cells from cell death

  2017cites this paper
• Cell penetrating peptides from agglutinin protein of Abrus precatorius facilitate the uptake of Imatinib mesylate.

  2016cites this paper
• Iso-suillin from Suillus flavus Induces Apoptosis in Human Small Cell Lung Cancer H446 Cell Line

  2016cites this paper
• Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer

  2016cites this paper
• SIRT3 inhibits prostate cancer by destabilizing oncoprotein c-MYC through regulation of the PI3K/Akt pathway

  2015cites this paper
• Huaier aqueous extract inhibits cervical cancer cell proliferation via JNK/p38 pathway.

  2015cites this paper