Comparison of transport properties of the reduced folate carrier and folate receptor in murine L1210 leukemia cells.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Biochemical Pharmacology

• Publication date

  1995-10-12

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/0006-2952(95)94097-YPMID 7488246
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Distinguishing between Folate Receptor-α-mediated Transport and Reduced Folate Carrier-mediated Transport in L1210 Leukemia Cells (*)

  1995cited by this paper
• Functional coupling between a bafilomycin A1-sensitive proton pump and a probenecid-sensitive folate transporter in human placental choriocarcinoma cells.

  1994cited by this paper
• Increased expression and genomic organization of a folate-binding protein homologous to the human placental isoform in L1210 murine leukemia cell lines with a defective reduced folate carrier.

  1994cited by this paper
• Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells.

  1994cited by this paper
• Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

  1994cited by this paper
• A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells.

  1994cited by this paper
• Isolation of a hamster cDNA clone coding for a function involved in methotrexate uptake.

  1994cited by this paper
• Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity.

  1994cited by this paper
• Multiple folate transport systems in L1210 cells.

  1992cited by this paper
• Potocytosis: sequestration and transport of small molecules by caveolae.

  1992cited by this paper
• The biological chemistry of folate receptors.

  1992cited by this paper
• Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates.

  1992cited by this paper
• Folate transport and binding by cultured human proximal tubule cells.

  1992cited by this paper
• The mechanism of receptor-mediated endocytosis.

  1991cited by this paper
• Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement.

  1991cited by this paper
• The folate receptor works in tandem with a probenecid-sensitive carrier in MA104 cells in vitro.

  1991cited by this paper
• ATP is required for receptor-mediated endocytosis in intact cells

  1990cited by this paper
• Folate-binding proteins.

  1990cited by this paper
• The glycophospholipid-linked folate receptor internalizes folate without entering the clathrin-coated pit endocytic pathway

  1990cited by this paper
• Characteristics of a novel transport system for folate compounds in wild-type and methotrexate-resistant L1210 cells.

  1990cited by this paper
• Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositol.

  1989cited by this paper
• The complete amino acid sequence of a human folate binding protein from KB cells determined from the cDNA.

  1989cited by this paper
• Membrane protein changes in an L1210 leukemia cell line with a translocation defect in the methotrexate-tetrahydrofolate cofactor transport carrier.

  1989cited by this paper
• Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells.

  1989cited by this paper
• Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA.

  1989cited by this paper
• Effect of osmolar and ionic composition of the extracellular fluid on transferrin endocytosis and exocytosis and iron uptake by reticulocytes

  1988cited by this paper
• Delivery of folates to the cytoplasm of MA104 cells is mediated by a surface membrane receptor that recycles.

  1988cited by this paper
• The effects on 4-aminoantifolates on 5-formyltetrahydrofolate metabolism in L1210 cells. A biochemical basis of the selectivity of leucovorin rescue.

  1987cited by this paper
• Properties of a folate binding protein (FBP) isolated from porcine kidney.

  1986cited by this paper
• The cellular pharmacology of methotrexate.

  1985cited by this paper
• Inhibitory effects of probenecid on the individual transport routes which mediate the influx and efflux of methotrexate in L1210 cells.

  1985cited by this paper
• Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: biological significance and implications for improved therapy of human cancer.

  1985cited by this paper
• Interaction of probenecid with methotrexate transport and release in the isolated rat hepatocyte in suspension.

  1984cited by this paper
• The folate-binding protein of rat kidney. Purification, properties, and cellular distribution.

  1984cited by this paper
• Transport of the antitumor antibiotic Cl-920 into L1210 leukemia cells by the reduced folate carrier system.

  1984cited by this paper
• Clathrin-coated vesicles from rat liver: enzymatic profile and characterization of ATP-dependent proton transport.

  1984cited by this paper
• Structural requirements for anion substrates of the methotrexate transport system in L1210 cells.

  1983cited by this paper
• Further studies on the charge-related alterations of methotrexate transport in Ehrlich ascites tumor cells by ionic liposomes: Correlation with liposome-cell association

  1982cited by this paper
• Anion exchange mechanism for transport of methotrexate in L1210 cells.

  1981cited by this paper
• Increased accumulation of methotrexate by murine tumor cells in vitro in the presence of probenecid which is mediated by a preferential inhibition of efflux.

  1981cited by this paper
• Binding properties of the 5-methyltetrahydrofolate/methotrexate transport system in L1210 cells.

  1980cited by this paper
• Effects of 2,4-dinitrophenol and other metabolic inhibitors on the bidirectional carrier fluxes, net transport, and intracellular binding of methotrexate in Ehrlich ascites tumor cells.

  1980cited by this paper
• THE CHARACTERISTICS OF THE MEMBRANE TRANSPORT OF AMETHOPTERIN AND THE NATURALLY OCCURRING FOLATES

  1971cited by this paper
• Transport energetics of the folic acid analogue, methotrexate, in L1210 leukemia cells. Enhanced accumulation by metabolic inhibitors.

  1969cited by this paper
• Carrier-mediated transport of the folic acid analogue, methotrexate, in the L1210 leukemia cell.

  1968cited by this paper
• Uptake as a Determinant of Methotrexate Response in Mouse Leukemias

  1965cited by this paper
• On the role of drug penetration in amethopterin resistance of Sarcoma-180 cells in vitro.

  1965cited by this paper

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  2016cites this paper
• Methotrexate influx via folate transporters into alveolar epithelial cell line A549.

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• Folate Transport in Mouse Cumulus-Oocyte Complexes and Preimplantation Embryos1

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  2011cites this paper
• Characterization of factors influencing the regulation of dietary folic acid deposition in the eggs

  2011cites this paper
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  2010cites this paper
• Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues

  2009cites this paper
• Differential usage of the transport systems for folic acid and methotrexate in normal human T-lymphocytes and leukemic cells.

  2009cites this paper
• Folic acid transport via high affinity carrier-mediated system in human retinoblastoma cells.

  2008cites this paper
• Pemetrexed: biochemical and cellular pharmacology, mechanisms, and clinical applications

  2007cites this paper
• Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells.

  2007cites this paper
• The Folate Receptor α Is Frequently Overexpressed in Osteosarcoma Samples and Plays a Role in the Uptake of the Physiologic Substrate 5-Methyltetrahydrofolate

  2007cites this paper
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  2006cites this paper
• Stereoselectivity of the reduced folate carrier in Caco-2 cells.

  2005cites this paper
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  2004cites this paper
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  2003cites this paper
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  2001cites this paper
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  2001cites this paper
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  2000cites this paper
• Cellular aspects of folate and antifolate membrane transport.

  2000cites this paper
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  1999cites this paper
• Characterization of the bile acid sensitive methotrexate carrier of rat liver cells

  1999cites this paper
• Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates.

  1999cites this paper
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  1998cites this paper
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  1998cites this paper
• Determination of folate transport pathways in cultured rat proximal tubule cells.

  1998cites this paper
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  1998cites this paper
• Characterization of folate transport mediated by a low pH route in mouse L1210 leukemia cells with defective reduced folate carrier function.

  1998cites this paper
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  1997cites this paper
• Comparison of methotrexate polyglutamylation in L1210 leukemia cells when influx is mediated by the reduced folate carrier or the folate receptor. Lack of evidence for influx route-specific effects.

  1996cites this paper