Efficacy and Safety of Adjunct Medications in ED Ultrasound‐Guided Nerve Blocks: A National Ultrasound‐Guided NeRVE (NURVE) Block Registry Study

Joseph Brown,Frederick Milgrim,Lachlan Driver,Melissa A. Meeker,Ryan Tucker,Nhu-Nguyen Le,A. Nagdev,Nicole Duggan,David A. Martin,Michael Heffler,Hamid Shokoohi,Andrea Dreyfuss,Christopher Fung,Leland Perice,Natalie Truong,S. Z. Jafry,Michael Macias,M. Riscinti,Andrew Goldsmith

Published 2025 in Academic Emergency Medicine

ABSTRACT

Ultrasound‐guided nerve blocks (UGNBs) are a core component of multimodal analgesia for acute pain management in emergency departments (EDs). In addition to using standard local anesthetics, adjuncts have been demonstrated to extend the duration of UGNBs. We evaluated the efficacy and safety of dexamethasone and epinephrine as anesthetic adjuncts in UGNBs in the ED.

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