Abnormalities of retinoblastoma gene expression in hematological malignancies.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Leukemia and Lymphoma

• Publication date

  1995-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3109/10428199509064923PMID 8580830
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Retinoblastoma protein expression is frequently altered in chronic lymphocytic leukemia.

  1994cited by this paper
• Decreased retinoblastoma protein expression in acute myeloblastic leukaemia is associated with the autonomous proliferation of clonogenic blasts

  1994cited by this paper
• Altered expression of the retinoblastoma gene product in human high grade non-Hodgkin's lymphomas.

  1994cited by this paper
• Levels of retinoblastoma protein expression in newly diagnosed acute myelogenous leukemia

  1994cited by this paper
• Absence of retinoblastoma protein expression results in autocrine production of interleukin-6 and promotes the autonomous growth of acute myeloid leukemia blast cells.

  1994cited by this paper
• Inactivation of tumor suppressor genes, p53 and Rb1, in plasma cell dyscrasias.

  1994cited by this paper
• Levels of retinoblastoma protein expression in newly diagnosed acute myelogenous leukemia.

  1994cited by this paper
• Autonomous growth of blast cells is associated with reduced survival in acute myeloblastic leukemia.

  1993cited by this paper
• Dams and sluices

  1993cited by this paper
• TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest

  1993cited by this paper
• High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics

  1993cited by this paper
• Braking the cycle.

  1993cited by this paper
• Cell cycle. Dams and sluices.

  1993cited by this paper
• Altered expression of the human retinoblastoma gene in monocytic leukaemias

  1993cited by this paper
• TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest.

  1993cited by this paper
• Transcriptional inhibition by the retinoblastoma protein.

  1993cited by this paper
• High frequency of monoallelic retinoblastoma gene deletion in B-cell chronic lymphoid leukemia shown by interphase cytogenetics.

  1993cited by this paper
• Autonomous proliferation of leukemic cells in vitro as a determinant of prognosis in adult acute myeloid leukemia.

  1993cited by this paper
• Functional interactions of the retinoblastoma protein with mammalian D-type cyclins.

  1993cited by this paper
• The role of the retinoblastoma gene in breast cancer development.

  1992cited by this paper
• E2F: a link between the Rb tumor suppressor protein and viral oncoproteins.

  1992cited by this paper
• Retinoblastoma gene deletions in b‐cell chronic lymphocytic leukemia

  1992cited by this paper
• Clinical implications of decreased retinoblastoma protein expression in acute myelogenous leukemia.

  1992cited by this paper
• Altered expression of retinoblastoma protein and known prognostic variables in locally advanced bladder cancer.

  1992cited by this paper
• Phosphorylation of the retinoblastoma protein by cdk2.

  1992cited by this paper
• Inactivation of the retinoblastoma gene in acute myelogenous leukaemia

  1992cited by this paper
• Autocrine growth factors and leukaemic haemopoiesis.

  1992cited by this paper
• Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2

  1992cited by this paper
• Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

  1992cited by this paper
• Inactivation of the retinoblastoma susceptibility gene in a human high grade non‐Hodgkin's lymphoma cell line

  1991cited by this paper
• Molecular genetic alterations in superficial and locally advanced human bladder cancer.

  1991cited by this paper
• Negative regulation of human c-fos expression by the retinoblastoma gene product

  1991cited by this paper
• Heterogeneous expression of the product of the retinoblastoma susceptibility gene in primary human leukemia cells.

  1991cited by this paper
• Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product.

  1991cited by this paper
• Inactivation of the retinoblastoma gene in human bladder and renal cell carcinomas.

  1991cited by this paper
• The retinoblastoma gene functions as a growth and tumor suppressor in human bladder carcinoma cells.

  1991cited by this paper
• Regulation of transforming growth factor beta 1 gene expression by the product of the retinoblastoma-susceptibility gene.

  1991cited by this paper
• Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia.

  1991cited by this paper
• Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia

  1991cited by this paper
• Release of early human hematopoietic progenitors from quiescence by antisense transforming growth factor beta 1 or Rb oligonucleotides

  1991cited by this paper
• Interleukin-6 is a prognostic factor in multiple myeloma.

  1991cited by this paper
• Interleukin-6 is a prognostic factor in multiple myeloma [letter] [see comments]

  1991cited by this paper
• Absence of the human retinoblastoma gene product in the megakaryoblastic crisis of chronic myelogenous leukemia.

  1991cited by this paper
• Inactivation of the retinoblastoma gene in human lymphoid neoplasms.

  1991cited by this paper
• Altered expression of the retinoblastoma gene product in human sarcomas.

  1990cited by this paper
• Interleukin-6 (IL-6) is an intermediate in IL-1-induced proliferation of leukemic human megakaryoblasts.

  1990cited by this paper
• Negative regulation of human c-fos expression by thes retinoblastoma gene product

  1990cited by this paper
• Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.

  1990cited by this paper
• Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

  1990cited by this paper
• Deletion of the human retinoblastoma gene in primary leukemias.

  1990cited by this paper
• Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.

  1990cited by this paper
• Expression and state of phosphorylation of the retinoblastoma susceptibility gene product in cycling and noncycling human hematopoietic cells.

  1990cited by this paper
• Endogenous interleukin-1 can regulate the autonomous growth of the blast cells of acute myeloblastic leukemia by inducing autocrine secretion of GM-CSF.

  1990cited by this paper
• Homozygous deletion of the retinoblastoma gene in an acute lymphoblastic leukemia (T) cell line.

  1990cited by this paper
• The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T.

  1990cited by this paper
• The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element.

  1989cited by this paper
• Interleukin-6 and interleukin-1 production in acute leukemia with monocytoid differentiation.

  1989cited by this paper
• Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product.

  1989cited by this paper
• The retinoblastoma protein is phosphorylated during specific phases of the cell cycle.

  1989cited by this paper
• The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product.

  1989cited by this paper
• Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation.

  1989cited by this paper
• Point mutational inactivation of the retinoblastoma antioncogene.

  1989cited by this paper
• Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.

  1989cited by this paper
• Structure of the human retinoblastoma gene.

  1989cited by this paper
• Heterogenous mechanisms of autocrine growth of AML blasts

  1989cited by this paper
• Participation of the cytokines interleukin 6, tumor necrosis factor-alpha, and interleukin 1-beta secreted by acute myelogenous leukemia blasts in autocrine and paracrine leukemia growth control.

  1989cited by this paper
• Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

  1988cited by this paper
• Altered expression of the retinoblastoma (RB) gene in small-cell carcinoma of the lung.

  1988cited by this paper
• Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.

  1988cited by this paper
• Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

  1988cited by this paper
• Identification of germline and somatic mutations affecting the retinoblastoma gene.

  1988cited by this paper
• Structural rearrangement of the retinoblastoma gene in human breast carcinoma.

  1988cited by this paper
• Chromosomal reorganization for the expression of recessive mutation of retinoblastoma susceptibility gene in the development of osteosarcoma.

  1988cited by this paper
• SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene.

  1988cited by this paper
• Autocrine generation and requirement of BSF-2/IL-6 for human multiple myelomas

  1988cited by this paper
• Inactivation of the retinoblastoma susceptibility gene in human breast cancers.

  1988cited by this paper
• In vitro expression of colony-stimulating factor genes by human acute myeloblastic leukemia cells.

  1988cited by this paper
• Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors.

  1987cited by this paper
• Human retinoblastoma susceptibility gene: cloning, identification, and sequence

  1987cited by this paper
• Structural evidence for the authenticity of the human retinoblastoma gene.

  1987cited by this paper
• The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

  1987cited by this paper
• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  1986cited by this paper
• Deletions of chromosome 13 in malignant hematologic disorders.

  1985cited by this paper
• Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma

  1983cited by this paper
• Regional assignment of genes for human esterase D and retinoblastoma to chromosome band 13q14.

  1980cited by this paper

• Cellular mechanisms of tumour suppression by the retinoblastoma gene

  2008cites this paper
• Differential diagnosis – chromosomal/molecular changes

  2008cites this paper
• Acquired Robertsonian translocations are not rare events in acute leukemia and lymphoma.

  2004cites this paper
• Targeted therapies in myeloid leukemia.

  2004cites this paper
• Anti-mitogenic effects of estradiol on vascular smooth muscle cells

  2003cites this paper
• [Molecular mechanisms controlling the cell cycle: fundamental aspects and implications for oncology].

  2001cites this paper
• Immunohistochemical expression of the p53, mdm2, p21/Waf-1, Rb, p16, Ki67, cyclin D1, cyclin A and cyclin B1 proteins and apoptotic index in T-cell lymphomas.

  2001cites this paper
• Mécanismes moléculaires contrôlant le cycle cellulaire : aspects fondamentaux et implications en cancérologie

  2001cites this paper
• Deletions in the 13q14 locus in adult lymphoblastic leukemia

  2000cites this paper
• Expression of p53, p21/waf1, bcl-2, bax, Rb and Ki67 proteins in Hodgkin's lymphomas.

  2000cites this paper
• Multiple myeloma: monoallelic deletions of the tumor suppressor genes TP53 and RB1 in long-term follow-up.

  2000cites this paper
• p16INK4A is regularly expressed in Hodgkin's disease: comparison with retinoblastoma, p53 and MDM2 protein status, and the presence of Epstein-Barr virus.

  1999cites this paper
• Co-expression and functional assay of human Rb and E2F1 proteins in yeast

  1999cites this paper
• Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia–lymphoma cells

  1998cites this paper
• Molecular epidemiology of hematological neoplasms--present status and future directions.

  1997cites this paper
• The impact of molecular cytogenetics on chronic lymphoid leukaemia.

  1997cites this paper
• Retinoblastoma protein family in cell cycle and cancer: A review

  1996cites this paper