The potential of multislice computed tomography in diagnosing coronary artery disease in heart transplant recipients: a literature review

Coronary artery disease remains a leading cause of graft failure after heart transplantation (HT). Because the transplanted heart is denervated, graft ischemia is typically asymptomatic, necessitating annual screening to detect cardiac allograft vasculopathy (CAV), monitor established coronary lesions, and evaluate in‑stent restenosis. The need for annual invasive coronary angiography, along with its associated risks, including potentially life-threatening complications, underscores the need for safer, yet equally effective, noninvasive diagnostic alternatives for evaluating coronary pathology in heart transplant recipients. Multislice computed tomography coronary angiography (MSCT–CAG) has been successfully employed in the diagnosis of ischemic heart disease (IHD) for many years and is well-established as a noninvasive alternative to conventional coronary angiography. This makes it particularly relevant to investigate its applicability and effectiveness in the post-transplant setting.

• Publication year

  2025

• Venue

  Russian Journal of Transplantology and Artificial Organs

• Publication date

  2025-09-03

• Fields of study

  Not labeled

• Identifiers
  DOI 10.15825/1995-1191-2025-3-97-109
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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