Outcome prediction of oestrogen receptor‐positive breast cancer based on a panel of oestrogen receptor‐regulated genes

S. Makhlouf,Nabeelah Almalki,Amera Sheha,N. Atallah,Asmaa Ibrahim,M. Toss,N. P. Mongan,E. Rakha

Published 2025 in Histopathology

ABSTRACT

The response of oestrogen receptor‐positive (ER+) breast cancers (BC) to endocrine therapy (ET) is variable. ER pathway‐regulated genes have been proposed to play a role in response to ET. In this study, we investigated the prognostic and predictive impacts of the expression of key ER‐regulated genes in BC.

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