Activity-dependent splicing: A game changer for proteome remodeling in the brain.

The brain's intricate neuronal circuits are continuously refined by external and internal stimuli throughout life. These plasticity events rely on a major proteome remodeling. Activity-dependent splicing has an unparalleled potential to instruct this proteome remodeling, enabling precise spatial and temporal control. This review examines recent progress in understanding activity-dependent splicing and highlights promising areas for future research into its role in brain plasticity.

• Publication year

  2025

• Venue

  Current Opinion in Neurobiology

• Publication date

  2025-09-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.conb.2025.103110PMID 40934741
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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