Data-Driven Discovery of a Key Regulator Cyclin A2 as a Promising Therapeutic Target in Hormone-Sensitive Cancers.

No abstract is available for this paper.

• Publication year

  2025

• Venue

  Molecular Biotechnology

• Publication date

  2025-09-11

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s12033-025-01504-7PMID 40936038
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Recent Advancements in the Application of Circulating Tumor DNA as Biomarkers for Early Detection of Cancers

  2024cited by this paper
• A pan-cancer landscape of centromere proteins in tumorigenesis and anticancer drug sensitivity

  2023cited by this paper
• g:Profiler—interoperable web service for functional enrichment analysis and gene identifier mapping (2023 update)

  2023cited by this paper
• Circulating tumor DNA (ctDNA) as a biomarker for lung cancer: Early detection, monitoring and therapy prediction.

  2023cited by this paper
• Cell division cycle associated 8 promotes the growth and inhibits the apoptosis of endometrial cancer cells by regulating cell cycle and P53/Rb signaling pathway.

  2023cited by this paper
• Protein regulator of cytokinesis 1: a potential oncogenic driver

  2023cited by this paper
• Targeting hormone-resistant breast cancer cells with docetaxel: a look inside the resistance

  2023cited by this paper
• A novel selective estrogen receptor degrader induces cell cycle arrest in breast cancer via ERα degradation and the autophagy-lysosome pathway.

  2023cited by this paper
• CCNA2 as an Immunological Biomarker Encompassing Tumor Microenvironment and Therapeutic Response in Multiple Cancer Types

  2022cited by this paper
• XPO1-Mediated EIF1AX Cytoplasmic Relocation Promotes Tumor Migration and Invasion in Endometrial Carcinoma

  2022cited by this paper
• Suppressing the PI3K/AKT Pathway by miR-30d-5p Mimic Sensitizes Ovarian Cancer Cells to Cell Death Induced by High-Dose Estrogen

  2022cited by this paper
• UALCAN: An update to the integrated cancer data analysis platform

  2022cited by this paper
• Association of a novel endometrial cancer biomarker panel with prognostic risk, platinum insensitivity, and targetable therapeutic options

  2021cited by this paper
• Molecular Characterization of Membrane Steroid Receptors in Hormone-Sensitive Cancers

  2021cited by this paper
• OncoDB: an interactive online database for analysis of gene expression and viral infection in cancer

  2021cited by this paper
• Ki-67 as a Prognostic Biomarker in Invasive Breast Cancer

  2021cited by this paper
• Web-Based Survival Analysis Tool Tailored for Medical Research (KMplot): Development and Implementation

  2021cited by this paper
• High-Throughput Proteomics and AI for Cancer Biomarker Discovery.

  2021cited by this paper
• Identification of Ten Mitosis Genes Associated with Tamoxifen Resistance in Breast Cancer

  2021cited by this paper
• Differential expression analysis in ovarian cancer: A functional genomics and systems biology approach

  2021cited by this paper
• Silencing of Nek2 suppresses the proliferation, migration and invasion and induces apoptosis of breast cancer cells by regulating ERK/MAPK signaling

  2021cited by this paper
• Integrated systems biology approach using gene network analysis to identify the important pathways and new potential drug targets for Neuroblastoma

  2021cited by this paper
• Expression and prognostic value of CDK1, CCNA2, and CCNB1 gene clusters in human breast cancer

  2021cited by this paper
• Oncogenic B-Myb Is Associated With Deregulation of the DREAM-Mediated Cell Cycle Gene Expression Program in High Grade Serous Ovarian Carcinoma Clinical Tumor Samples

  2021cited by this paper
• Cytotoxicity Evaluation of Chloroquine and Hydroxychloroquine in Multiple Cell Lines and Tissues by Dynamic Imaging System and Physiologically Based Pharmacokinetic Model

  2020cited by this paper
• Expression levels of BCL2 and MKI67 in endometrial polyps in postmenopausal women and their correlation with obesity.

  2020cited by this paper
• Endocrine Risk Factors of Endometrial Cancer: Polycystic Ovary Syndrome, Oral Contraceptives, Infertility, Tamoxifen

  2020cited by this paper
• Pitfalls in Cancer Biomarker Discovery and Validation with Emphasis on Circulating Tumor DNA

  2020cited by this paper
• Gene interaction network studies to decipher the multi-drug resistance mechanism in Salmonella enterica serovar typhi CT18 reveal potential drug targets.

  2020cited by this paper
• Weighted gene co-expression network analysis identifies CCNA2 as a treatment target of prostate cancer through inhibiting cell cycle

  2020cited by this paper
• S2ORC: The Semantic Scholar Open Research Corpus

  2020cited by this paper
• Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer

  2020cited by this paper
• Intercellular adhesion molecule-1 and S-100β in sevoflurane combined with epidural anesthesia for radical resection of lung cancer

  2019cited by this paper
• E2F1 as a molecular drug target in ovarian cancer

  2019cited by this paper
• CDCA8 is a key mediator of estrogen-stimulated cell proliferation in breast cancer cells.

  2019cited by this paper
• ROCplot.org: Validating predictive biomarkers of chemotherapy/hormonal therapy/anti‐HER2 therapy using transcriptomic data of 3,104 breast cancer patients

  2019cited by this paper
• Bioinformatics prediction and analysis of hub genes and pathways of three types of gynecological cancer

  2019cited by this paper
• Cell Division Cycle Associated 8 Is a Key Regulator of Tamoxifen Resistance in Breast Cancer

  2019cited by this paper
• Analysis of gene expression profiles and protein-protein interaction networks in multiple tissues of systemic sclerosis

  2019cited by this paper
• CCNA2 acts as a novel biomarker in regulating the growth and apoptosis of colorectal cancer

  2018cited by this paper
• Repeated mutKRAS ctDNA measurements represent a novel and promising tool for early response prediction and therapy monitoring in advanced pancreatic cancer

  2018cited by this paper
• Correlation analysis in clinical and experimental studies

  2018cited by this paper
• Strategies to design clinical studies to identify predictive biomarkers in cancer research.

  2017cited by this paper
• Making Meaningful Clinical Use of Biomarkers

  2017cited by this paper
• The Gene Ontology and the Meaning of Biological Function.

  2017cited by this paper
• Targeting mitotic pathways for endocrine-related cancer therapeutics.

  2017cited by this paper
• A Photoaffinity Labeling-Based Chemoproteomics Strategy for Unbiased Target Deconvolution of Small Molecule Drug Candidates.

  2017cited by this paper
• CCNA2 facilitates epithelial-to-mesenchymal transition via the integrin αvβ3 signaling in NSCLC.

  2017cited by this paper
• Multiple sclerosis: clinical profiling and data collection as prerequisite for personalized medicine approach

  2016cited by this paper
• Identification of candidate biomarkers and analysis of prognostic values in ovarian cancer by integrated bioinformatics analysis

  2016cited by this paper
• CDKN3 knockdown reduces cell proliferation, invasion and promotes apoptosis in human ovarian cancer.

  2015cited by this paper
• cytoHubba: identifying hub objects and sub-networks from complex interactome

  2014cited by this paper
• Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (review).

  2014cited by this paper
• Upregulation of NEK2 is associated with drug resistance in ovarian cancer.

  2014cited by this paper
• Convergence of G Protein–Coupled Receptor and S-Nitrosylation Signaling Determines the Outcome to Cardiac Ischemic Injury

  2013cited by this paper
• Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

  2013cited by this paper
• Zinc fingers and homeoboxes 2 inhibits hepatocellular carcinoma cell proliferation and represses expression of Cyclins A and E.

  2012cited by this paper
• Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells

  2007cited by this paper
• Mechanisms of tamoxifen resistance.

  2004cited by this paper
• An automated method for finding molecular complexes in large protein interaction networks

  2003cited by this paper
• Survival Analysis Part I: Basic concepts and first analyses

  2003cited by this paper
• Genetics 101: detecting mutations in human genes.

  2002cited by this paper
• KEGG: Kyoto Encyclopedia of Genes and Genomes

  2000cited by this paper

• No citing papers are available for this paper.