Promising roles and current limitations of bortezomib-based desensitization for kidney transplantation.

Hee Byung Koh,Jaeseok Yang

Published 2025 in Kidney Research and Clinical Practice

ABSTRACT

Many transplant candidates show the presence of pre-formed antibodies against human leukocyte antigens (HLA), known as HLA sensitization, which poses a major immunological barrier to successful transplantation. Approximately 30%–40% of patients on the kidney transplant waiting list are sensitized to HLA

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