Long-term Trends in Major Amputations for the state of Pennsylvania.

INTRODUCTION Recent reports have suggested the incidence of major amputations in the United States may be increasing. Despite rapidly increasing closed vascular surgery, drastically improved diabetes management and medications, those with diabetes mellitus, in rural or distressed communities appear to be suffering a disproportionately high rate of major amputation. Identification of the specific areas and populations at risk is urgently needed to address the disparity and rising incidence of a totally preventable devastating health outcome. This population-based study using an all-payor dataset provides a most recent assessment of major amputations in Pennsylvania. METHOD The state of Pennsylvania hospital inpatient database was accessed to capture major amputations with a PAD/CLTI diagnosis from 2010 to 2023. RESULTS There were 25,645 unique patients in our cohort. The number of patients suffering major amputation rose modestly at 1.3 % yearly. The major amputation rate rose from 2.1/10,000 to 2.5/10,000. Average age at amputation became younger over time. CONCLUSION The rate of major amputations in Pennsylvania rose modestly. Black men in distressed communities suffered a disproportionately high rate of amputation at increasingly younger ages. More states need to identify the populations and geographic areas suffering high rates of major amputation to enable a better understanding of the overall increase in major amputations in the United States. These studies need to use a standard cohort selection scheme and reporting method to allow meaningful understanding of the populations at risk of major amputation.

• Publication year

  2025

• Venue

  Journal of Vascular Surgery

• Publication date

  2025-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jvs.2025.09.055PMID 41067586
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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