Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Neurology Neurosurgery & Psychiatry

• Publication date

  2016-08-24

• Fields of study

  Medicine

• Identifiers
  DOI 10.1136/jnnp-2016-313722PMID 27559181
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Class II HLA interactions modulate genetic risk for multiple sclerosis

  2015cited by this paper
• Latitude and HLA-DRB1 alleles independently affect the emergence of cerebrospinal fluid IgG abnormality in multiple sclerosis

  2015cited by this paper
• Association between multiple sclerosis risk-associated SNPs and relapse and disability – a prospective cohort study

  2014cited by this paper
• The influence of combined genotypes of the HLADRB1*1501 and CD24 single nucleotide polymorphism on disease severity of Iranian multiple sclerosis patients.

  2014cited by this paper
• Cumulative Effects of Variants Identified by Genome-wide Association Studies in IgA Nephropathy

  2014cited by this paper
• Illumina human exome genotyping array clustering and quality control

  2014cited by this paper
• Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects

  2013cited by this paper
• Novel modulating effects of PKC family genes on the relationship between serum vitamin D and relapse in multiple sclerosis

  2013cited by this paper
• Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

  2013cited by this paper
• The physical anthropometry, lifestyle habits and blood pressure of people presenting with a first clinical demyelinating event compared to controls: The Ausimmune study

  2013cited by this paper
• A genome-wide association study in progressive multiple sclerosis

  2012cited by this paper
• 2010 McDonald criteria for diagnosing pediatric multiple sclerosis

  2012cited by this paper
• Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

  2011cited by this paper
• HLA B*44: Protective effects in MS susceptibility and MRI outcome measures

  2011cited by this paper
• The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry

  2011cited by this paper
• Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition

  2011cited by this paper
• HLA associations with multiple sclerosis in Greece.

  2011cited by this paper
• Multiple Sclerosis Susceptibility-Associated SNPs Do Not Influence Disease Severity Measures in a Cohort of Australian MS Patients

  2010cited by this paper
• HLA B*44

  2010cited by this paper
• Score and Cardiovascular Events in Women Association Between a Literature-Based Genetic Risk

  2010cited by this paper
• HLA-DRB1 allele heterogeneity influences multiple sclerosis severity as well as risk in Western Australia.

  2010cited by this paper
• Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

  2009cited by this paper
• Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophy

  2009cited by this paper
• Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20

  2009cited by this paper
• Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis.

  2006cited by this paper
• Competing interests: none declared.

  2006cited by this paper
• Principal components analysis corrects for stratification in genome-wide association studies

  2006cited by this paper
• Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”

  2005cited by this paper
• Recommended diagnostic criteria for multiple sclerosis: Guidelines from the international panel on the diagnosis of multiple sclerosis

  2001cited by this paper
• HLA‐DR15 is associated with lower age at onset in multiple sclerosis

  2000cited by this paper
• Relapses and progression of disability in multiple sclerosis.

  2000cited by this paper
• Rating neurologic impairment in multiple sclerosis

  1983cited by this paper
• On the regression analysis of multivariate failure time data

  1981cited by this paper
• A Simple Sequentially Rejective Multiple Test Procedure

  1979cited by this paper

• Diet-dependent acid-base load is not associated with rate of relapse, annualised disability change, FLAIR, and black hole lesion volume on MRI in a prospective cohort study of those with multiple sclerosis.

  2025cites this paper
• Limited overlap between genetic effects on disease susceptibility and disease survival

  2025cites this paper
• Serum levels of tumor necrosis factor and TNFRSF1A gene polymorphisms in Egyptian multiple sclerosis patients: the influence on susceptibility and severity.

  2025cites this paper
• A pro-inflammatory diet in people with multiple sclerosis is associated with an increased rate of relapse and increased FLAIR lesion volume on MRI in early multiple sclerosis: A prospective cohort study

  2023cites this paper
• Limited overlap between genetic effects on disease susceptibility and disease survival

  2023cites this paper
• Higher dietary quality is prospectively associated with lower MRI FLAIR lesion volume, but not with hazard of relapse, change in disability or black hole volume in people with Multiple Sclerosis.

  2023cites this paper
• Apraxia and dementia severity in Alzheimer’s disease: a systematic review

  2023cites this paper
• Differences in MS clinical and epidemiological characteristics between Ashkenazi and non-Ashkenazi Jewish patients in Israel: a retrospective single center study

  2022cites this paper
• Cognitive, Psychiatric, and Motor Symptoms–Based Algorithmic Approach to Differentiate Among Various Types of Dementia Syndromes

  2022cites this paper
• Impaired Affordance Perception as the Basis of Tool Use Deficiency in Alzheimer’s Disease

  2022cites this paper
• Comparing Individuals With PPA to Individuals With AD: Cognitive and Linguistic Profiles

  2022cites this paper
• Evaluation of the Dementia Apraxia Test in Parkinson’s Disease Patients

  2022cites this paper
• Improving nutrition and hydration in older people with dementia in care homes.

  2022cites this paper
• Нейроофтальмологічні аспекти розсіяного склерозу

  2022cites this paper
• Novel plasma and brain proteins that are implicated in multiple sclerosis.

  2022cites this paper
• Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis

  2022cites this paper
• Literatur

  2022cites this paper
• Preliminary validation of the apraxia battery for adults-second edition (ABA-2) in Greek patients with dementia

  2021cites this paper
• Genetic, Environmental and Lifestyle Determinants of Accelerated Telomere Attrition as Contributors to Risk and Severity of Multiple Sclerosis

  2021cites this paper
• Developing a clinical–environmental–genotypic prognostic index for relapsing-onset multiple sclerosis and clinically isolated syndrome

  2021cites this paper
• The Cognitive Scale of Basic and Instrumental Activities of Daily Living for Multidomain Mild Cognitive Impairment and Dementia Patients: Validation of its Extended Version

  2021cites this paper
• Liver kinase B1 rs9282860 polymorphism and risk for multiple sclerosis in White and Black Americans.

  2021cites this paper
•  Limb apraxia profiles in different clinical samples

  2020influential citation
• Pathophysiologic Insights from Biomarker Studies in Neurological Disorders

  2020cites this paper
• Limb and face apraxias in frontotemporal dementia: A systematic scoping review.

  2020cites this paper
• Genomic, proteomic, and systems biology approaches in biomarker discovery for multiple sclerosis.

  2020cites this paper
• Anti-MOG antibody–associated disorders: differences in clinical profiles and prognosis in Japan and Germany

  2020cites this paper
• Neurological examination: what do psychiatrists need to know?

  2020cites this paper
• Genetic model of MS severity predicts future accumulation of disability

  2020cites this paper
• Lipid-related genetic polymorphisms significantly modulate the association between lipids and disability progression in multiple sclerosis

  2019cites this paper
• Psychological and Cognitive Markers of Behavioral Variant Frontotemporal Dementia–A Clinical Neuropsychologist's View on Diagnostic Criteria and Beyond

  2019cites this paper
• Ernährung und Demenz

  2019cites this paper
• Environmental and genetic risk factors for MS: an integrated review

  2019cites this paper
• I think, therefore I forget – using experimental simulation of dementia to understand functional cognitive disorders

  2019cites this paper
• Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis

  2019cites this paper
• The Association Between Vitamin D and Multiple Sclerosis Risk: 1,25(OH)2D3 Induces Super-Enhancers Bound by VDR

  2019influential citation
• Polymorphisms in the CIITA −168A/G (rs3087456) and CIITA +1614G/C (rs4774) may influence severity in multiple sclerosis patients

  2018cites this paper
• Human miR-26a-5p regulates the glutamate transporter SLC1A1 (EAAT3) expression. Relevance in multiple sclerosis.

  2018cites this paper
• Genomic Effects of the Vitamin D Receptor: Potentially the Link between Vitamin D, Immune Cells, and Multiple Sclerosis

  2018cites this paper
• Genotype and Phenotype in Multiple Sclerosis—Potential for Disease Course Prediction?

  2018cites this paper
• Health outcomes and adherence to a healthy lifestyle after a multimodal intervention in people with multiple sclerosis: Three year follow-up

  2018cites this paper
• Genetics of Multiple Sclerosis: An Overview and New Directions.

  2018cites this paper
• Onset Symptoms, Tobacco Smoking, and Progressive-Onset Phenotype Are Associated With a Delayed Onset of Multiple Sclerosis, and Marijuana Use With an Earlier Onset

  2018cites this paper
• Apraxia profiles—A single cognitive marker to discriminate all variants of frontotemporal lobar degeneration and Alzheimer's disease

  2018cites this paper
• TNFRSF1A polymorphisms and their role in multiple sclerosis susceptibility and severity in the Slovak population

  2018cites this paper
• Cholinergic and purinergic systems: A key to multiple sclerosis?

  2018cites this paper
• Apraxia screening predicts Alzheimer pathology in frontotemporal dementia

  2018cites this paper
• A neuropathologic diagnosis of Alzheimer’s disease in an older adult with HIV-associated neurocognitive disorder

  2018cites this paper
• Estimation of annual probabilities of changing disability levels in Australians with relapsing-remitting multiple sclerosis

  2018cites this paper
• Inferring Cognitive Wellness from Motor Patterns

  2018cites this paper
• Rehabilitation for Individuals with Dementia: Facilitating Success

  2018influential citation
• Apraxias

  2018cites this paper
• Subsets of activated monocytes and markers of inflammation in incipient and progressed multiple sclerosis

  2017cites this paper
• Alzheimer's disease: with apraxia

  2017cites this paper
• Can cognitive assessment really discriminate early stages of Alzheimer’s and behavioural variant frontotemporal dementia at initial clinical presentation?

  2017cites this paper
• Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis

  2017cites this paper
• How to Diagnose an Alzheimer Disease?

  2017cites this paper
• Significance of genetic polymorphisms in long non-coding RNA AC079767.4 in tuberculosis susceptibility and clinical phenotype in Western Chinese Han population

  2017cites this paper
• Why patients with dementia need a motor examination

  2016cites this paper
• Multiple sclerosis: Biomarkers and genetic variants reflect disease course in multiple sclerosis

  2016cites this paper