Alterations in glutamate receptor 2/3 subunits and amyloid precursor protein expression during the course of Alzheimer’s disease and Lewy body variant

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Acta Neuropathologica

• Publication date

  1997-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s004010050748PMID 9444355
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neuropathological stageing of Alzheimer-related changes

  2004cited by this paper
• Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease

  1996cited by this paper
• Profound Loss of Layer II Entorhinal Cortex Neurons Occurs in Very Mild Alzheimer’s Disease

  1996cited by this paper
• Entorhinal cortex modules of the human brain

  1996cited by this paper
• Neurotrophic and Neuroprotective Effects of hAPP in Transgenic Mice a

  1996cited by this paper
• Metabotropic Glutamate Receptors Regulate APP Processing in Hippocampal Neurons and Cortical Astrocytes Derived from Fetal Rats a

  1996cited by this paper
• Current Concepts of Excitotoxicity

  1996cited by this paper
• Increased Activity‐Regulating and Neuroprotective Efficacy of α‐Secretase‐Derived Secreted Amyloid Precursor Protein Conferred by a C‐Terminal Heparin‐Binding Domain

  1996cited by this paper
• Making the diagnosis of mixed and non-Alzheimer's dementias.

  1995cited by this paper
• Opposing regulation of amyloid precursor protein by ionotropic and metabotropic glutamate receptors.

  1995influential reference
• Genetic evidence that the Lewy body variant is indeed a phenotypic variant of Alzheimer's disease.

  1995cited by this paper
• Levels and Alternative Splicing of Amyloid β Protein Precursor (APP) Transcripts in Brains of APP Transgenic Mice and Humans with Alzheimer's Disease (*)

  1995cited by this paper
• Image analysis of β-amyloid load in Alzheimer's disease and relation to dementia severity

  1995cited by this paper
• Reduction of AMPA-selective glutamate receptor subunits in the entorhinal cortex of patients with Alzheimer's disease pathology: a biochemical study.

  1995cited by this paper
• Making the diagnosis of mixed and non-Alzheimer's dementias.

  1995cited by this paper
• Decreases in protease nexins in Alzheimer's disease brain

  1995cited by this paper
• Calcineurin (phosphatase 2B) is present in neurons containing neurofibrillary tangles and in a subset of senile plaques in Alzheimer's disease.

  1995cited by this paper
• Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.

  1995cited by this paper
• Promoter activity of the gene encoding the beta-amyloid precursor protein is up-regulated by growth factors, phorbol ester, retinoic acid and interleukin-1.

  1995cited by this paper
• Decreases in protease nexins in Alzheimer's disease brain.

  1995cited by this paper
• The Effects of Alzheimer's Disease, Other Dementias, and Premortem Course on β‐Amyloid Precursor Protein Messenger RNA in Frontal Cortex

  1994cited by this paper
• Increase of synaptic density and memory retention by a peptide representing the trophic domain of the amyloid beta/A4 protein precursor.

  1994cited by this paper
• Synaptic and neuritic alterations during the progression of Alzheimer's disease.

  1994cited by this paper
• Synapse alterations in the hippocampal-entorhinal formation in Alzheimer's disease with and without Lewy body disease.

  1994cited by this paper
• Differences in the pattern of hippocampal neuronal loss in normal ageing and Alzheimer's disease.

  1994cited by this paper
• Selective RNA editing and subunit assembly of native glutamate receptors.

  1994cited by this paper
• The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1

  1994cited by this paper
• Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the β-amyloid precursor protein

  1993cited by this paper
• Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

  1993cited by this paper
• On the origin of Alzheimer's disease: a hypothesis.

  1993cited by this paper
• Plaque‐Only Alzheimer Disease is Usually the Lewy Body Variant, and Vice Versa

  1993cited by this paper
• Cellular specificity and regional distribution of amyloid beta protein precursor alternative transcripts are unaltered in Alzheimer hippocampal formation.

  1993cited by this paper
• Brain S-adenosylmethionine decarboxylase activity is increased in Alzheimer's disease.

  1993cited by this paper
• Localization of amyloid precursor protein in GAP43-immunoreactive aberrant sprouting neurites in Alzheimer's disease.

  1992cited by this paper
• Lewy body disease.

  1992cited by this paper
• Entorhinal neurofibrillary tangles in Alzheimer disease with Lewy bodies.

  1991cited by this paper
• The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway.

  1990cited by this paper
• The Alzheimer amyloid precursor-related transcript lacking the beta/A4 sequence is specifically increased in Alzheimer's disease brain.

  1990cited by this paper
• Fibroblast growth factor induces beta-amyloid precursor mRNA in glial but not neuronal cultured cells.

  1990cited by this paper
• Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease.

  1990cited by this paper
• Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease.

  1989cited by this paper
• Excitatory amino acids and Alzheimer's disease.

  1989cited by this paper
• Amyloid protein precursor messenger RNAs: differential expression in Alzheimer's disease.

  1988cited by this paper
• Differential regulation of amyloid-beta-protein mRNA expression within hippocampal neuronal subpopulations in Alzheimer disease.

  1988cited by this paper
• Selective reduction of mRNA for the beta-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brains.

  1988cited by this paper
• Alzheimer's disease: Glutamate depletion in the hippocampal perforant pathway zone

  1987cited by this paper
• Perforant pathway changes and the memory impairment of Alzheimer's disease

  1986influential reference

• The glutamatergic system in Alzheimer’s disease: a systematic review with meta-analysis

  2024cites this paper
• β-amyloid−driven synaptic depression requires PDZ protein interaction at AMPA-receptor subunit GluA3

  2021cites this paper
• Regional transcriptome analysis of AMPA and GABAA receptor subunit expression generates E/I signatures of the human brain

  2020cites this paper
• Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease

  2020cites this paper
• Age-Dependent Shift of AMPA Receptors From Synapses to Intracellular Compartments in Alzheimer’s Disease: Immunocytochemical Analysis of the CA1 Hippocampal Region in APP/PS1 Transgenic Mouse Model

  2020cites this paper
• Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β

  2017cites this paper
• ShcC proteins: brain aging and beyond.

  2015cites this paper
• Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia

  2015cites this paper
• Aβ’s effect on long term memory: a top-down approach in Lymnaea stagnalis

  2015cites this paper
• Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease.

  2014cites this paper
• Multiple pathogenic proteins implicated in neuronopathic Gaucher disease mice.

  2014cites this paper
• Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model

  2014cites this paper
• Cortical astroglial atrophy in ageing and Alzheimer's disease

  2013cites this paper
• Aβ(1-42) induced metabolic effects in a stem cell derived neuron and astrocyte network

  2013cites this paper
• MODELLING AND DRUG DESIGNING OF GLUTAMATE RECEPTOR INVOLVED IN ALZHEIMER ’ S DISEASE

  2012cites this paper
• Chronic treatment with rivastigmine in patients with Alzheimer's disease: a study on primary motor cortex excitability tested by 5 Hz-repetitive transcranial magnetic stimulation.

  2012cites this paper
• Post-synaptic scaffolding protein interactions with glutamate receptors in synaptic dysfunction and Alzheimer's disease.

  2011cites this paper
• Reduced levels of the tyrosine phosphatase STEP block beta amyloid‐mediated GluA1/GluA2 receptor internalization

  2011cites this paper
• DHEA and Alzheimer's Disease

  2011cites this paper
• Glutamate and Neurodegenerative Disease

  2010cites this paper
• Alterations in mGluR5 Expression and Signaling in Lewy Body Disease and in Transgenic Models of Alpha-Synucleinopathy – Implications for Excitotoxicity

  2010cites this paper
• Altered distribution of mGlu2 receptors in β-amyloid-affected brain regions of Alzheimer cases and aged PS2APP mice.

  2010cites this paper
• Biochemical and pathological correlates of cognitive and behavioural change in DLB/PDD

  2009cites this paper
• Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease.

  2009cites this paper
• Cholinergic and glutamatergic alterations beginning at the early stages of Alzheimer disease: participation of the phospholipase A2 enzyme

  2008cites this paper
• Amyloid beta peptides and glutamatergic synaptic dysregulation.

  2008cites this paper
• Glutamate-glutamine cycling in Alzheimer's disease.

  2007cites this paper
• Cholinergic and other neurotransmitter mechanisms in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies

  2007cites this paper
• Lysosomal Dysfunction Produces Distinct Alterations in Synaptic &agr;-Amino-3-Hydroxy-5-Methylisoxazolepropionic Acid and N-Methyl-D-Aspartate Receptor Currents in Hippocampus

  2007cites this paper
• Impaired metabotropic glutamate receptor/phospholipase C signaling pathway in the cerebral cortex in Alzheimer's disease and dementia with Lewy bodies correlates with stage of Alzheimer's-disease-related changes.

  2005cites this paper
• The role of metabotropic glutamate receptors in Alzheimer's disease.

  2004cites this paper
• Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer’s disease

  2004cites this paper
• Differences in olfactory and visual memory in patients with pathologically confirmed Alzheimer's disease and the Lewy body variant of Alzheimer's disease

  2004cites this paper
• Lysosomal Activation Is a Compensatory Response Against Protein Accumulation and Associated Synaptopathogenesis—An Approach for Slowing Alzheimer Disease?

  2003cites this paper
• INTERACTION OF MUSCARINIC ACETYLCHOLINE AND N- METHYL-D-ASPARTATE -TYPE GLUTAMATE RECEPTORS IN THE REGULATION OF SPATIAL LEARNING AND MEMORY

  2003cites this paper
• JUHANA AURA INTERACTION OF MUSCARINIC ACETYLCHOLINE AND N-METHYL-D-ASPARTATE-TYPE GLUTAMATE RECEPTORS IN THE REGULATION OF SPATIAL LEARNING AND MEMORY

  2003cites this paper
• Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticity.

  2003cites this paper
• Alterations in cholinergic and non‐cholinergic neurotransmitter receptor densities in transgenic Tg2576 mouse brain with β‐amyloid plaque pathology

  2003cites this paper
• Differential Regulation of Glutamate Receptors in Alzheimer’s Disease

  2002cites this paper
• Locally reduced levels of acidic FGF lead to decreased expression of 28‐kDa calbindin and contribute to the selective vulnerability of the neurons in the entorhinal cortex in Alzheimer's disease

  2001cites this paper
• Accumulation of C-terminally truncated tau protein associated with vulnerability of the perforant pathway in early stages of neurofibrillary pathology in Alzheimer's disease.

  2001cites this paper
• Glutamate receptor dysregulation in the hippocampus of transgenic mice carrying mutated human amyloid precursor protein.

  2001cites this paper
• Glutamatergic Neurotransmission, Aluminium and Alzheimer’s Disease

  2001cites this paper
• Abnormal glutamate transport function in mutant amyloid precursor protein transgenic mice.

  2000cites this paper
• Age-related loss of the AMPA receptor subunits GluR2/3 in the human nucleus basalis of Meynert.

  2000cites this paper
• The AMPAR subunit GluR2: still front and center-stage.

  2000cites this paper
• A unifying hypothesis of Alzheimer's disease. II. Pathophysiological processes

  1999cites this paper
• Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer's disease.

  1999cites this paper
• Inhibition of AMPA responses by mutated presenilin 1

  1999cites this paper
• Caspase Dependent DNA Fragmentation Might Be Associated with Excitotoxicity in Alzheimer Disease

  1998cites this paper