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Clinical Management and Outcomes of Ectopic Pregnancies: Experience From Sohar Hospital Over Three Years

Samiha Samad,Kaukab Tashfeen,Naseem Anjum,Sabira Khuda Bakhsh,Sheeba Burney,Sakina Noushad Saleem

Published 2025 in Cureus

ABSTRACT

Background Ectopic pregnancy is a potentially life-threatening condition requiring timely diagnosis and appropriate management. This study aims to evaluate the clinical presentation, management strategies, and treatment outcomes of women with ectopic pregnancy at a tertiary care hospital in Oman over a three-year period. Materials and methods We retrospectively reviewed 404 ectopic pregnancy cases from 2020 to 2022. Patients received methotrexate or surgical treatment. Patients were evaluated for success rate, complications, hospital stay, and need for further intervention using t-tests, chi-square, and multivariate models. Results No significant differences were found between groups regarding age, gravidity, parity, prior ectopic pregnancy, pelvic inflammatory disease, or pelvic surgery. Clinical presentations were similar, though hemodynamic instability was more frequent in the surgical group (15.3% vs. 6.4%, p = 0.01), independently predicting surgical intervention (adjusted odds ratio (AOR) = 2.65, 95% CI: 1.22-5.75). Surgical management yielded a higher success rate (97.6% vs. 85.9%, p < 0.001; AOR = 4.85, 95% CI: 2.01-11.7). Laparoscopy was the predominant surgical method (79.8%), while 28.8% of medically treated patients received multidose methotrexate. Complication rates were comparable (7.7% vs. 7.3%, p = 0.88), but hospital stay was longer in the surgical group (4.8 vs. 2.4 days, p < 0.001). Additional interventions were more common in the medical group (5.1% vs. 0.8%, p = 0.016; AOR = 6.78, 95% CI: 1.35-33.9). Tubal ectopic pregnancies predominated (81.2%), with treatment modality significantly associated with ectopic site (p = 0.0239). Management type was significantly linked to treatment outcome (χ² = 14.5, p < 0.001). Conclusion Surgical management demonstrates higher efficacy and reduced need for retreatment, particularly in hemodynamically unstable or non-tubal ectopic pregnancies. Treatment decisions should be guided by clinical stability and anatomical site to optimize outcomes.

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