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Obstructive sleep apnea in psoriatic arthritis: A polysomnography-based Evaluation

Mohammad Mustafa,S. Attar,Omar Kanbr,Y. Bawazir,A. Bamagoos,Ayah M. Boudal,Faris Alhejaili,S. Wali

Published 2025 in Medicine

ABSTRACT

Obstructive sleep apnea (OSA) is a challenging condition affecting 9% to 38% of people worldwide. However, its prevalence in patients with psoriatic arthritis (PsA) remains inconclusive. This study aimed to investigate the point-prevalence of OSA in patients with PsA using polysomnography (PSG) the gold-standard diagnostic method for OSA. Diagnosis of OSA was confirmed via standardized PSG utilizing the American Academy of sleep (AASM) recommendations. PsA disease activity was assessed using the disease activity index for psoriatic arthritis (DAPSA) and Health Assessment Questionnaire-Disability Index (HAQ-DI). The point-prevalence of OSA among the 42 PsA patients who underwent PSG was 50%, with 36% exhibiting moderate-to-severe OSA. No significant associations were identified between OSA occurrence and PsA disease activity assessed by DAPSA or HAQ-DI (P > .05). Older age (OR = 1.17, 95% CI = 1.07–1.27, P = .001) as well as greater BMI, which showed a trend toward significance (OR = 1.23, 95% CI = 0.99–1.52, P = .055), were predictors of OSA in patients with PsA. Although there was no correlation between PsA disease activity and OSA, our study highlights a higher prevalence of OSA among patients with PsA compared with the population in the same region, as well as reported literature.

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