The Unique Dopamine/Ecdysteroid Receptor Modulates Ethanol-Induced Sedation in Drosophila

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Neuroscience

• Publication date

  2016-04-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1523/JNEUROSCI.3774-15.2016PMID 27098705PMCID PMC4837687
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• GPCR-mediated rapid, non-genomic actions of steroids: comparisons between DmDopEcR and GPER1 (GPR30).

  2014cited by this paper
• The GPCR membrane receptor, DopEcR, mediates the actions of both dopamine and ecdysone to control sex pheromone perception in an insect

  2014cited by this paper
• Expression of Multiple Transgenes from a Single Construct Using Viral 2A Peptides in Drosophila

  2014influential reference
• Agonist-independent GPCR activity regulates anterior-posterior targeting of olfactory sensory neurons.

  2013cited by this paper
• The evolution of Drosophila melanogaster as a model for alcohol research.

  2013cited by this paper
• A Novel Role for Ecdysone in Drosophila Conditioned Behavior: Linking GPCR-Mediated Non-canonical Steroid Action to cAMP Signaling in the Adult Brain

  2013influential reference
• Involvement of the G-Protein-Coupled Dopamine/Ecdysteroid Receptor DopEcR in the Behavioral Response to Sex Pheromone in an Insect

  2013cited by this paper
• NIH Image to ImageJ: 25 years of image analysis

  2012cited by this paper
• KCNQ Channels Show Conserved Ethanol Block and Function in Ethanol Behaviour

  2012cited by this paper
• Drosophila melanogaster as a model to study drug addiction

  2012cited by this paper
• Visualizing neuromodulation in vivo: TANGO-mapping of dopamine signaling reveals appetite control of sugar sensing.

  2012cited by this paper
• Signalling bias in new drug discovery: detection, quantification and therapeutic impact

  2012cited by this paper
• Acute ethanol responses in Drosophila are sexually dimorphic

  2012influential reference
• Epidermal Growth Factor Receptor (EGFR) Crosstalks in Liver Cancer

  2011cited by this paper
• Identification of cholesterol recognition amino acid consensus (CRAC) motif in G-protein coupled receptors.

  2011influential reference
• arouser reveals a role for synapse number in the regulation of ethanol sensitivity.

  2011cited by this paper
• Crystal Structure of the β2Adrenergic Receptor-Gs protein complex

  2011cited by this paper
• A Pair of Dopamine Neurons Target the D1-Like Dopamine Receptor DopR in the Central Complex to Promote Ethanol-Stimulated Locomotion in Drosophila

  2010influential reference
• The developmental transcriptome of Drosophila melanogaster

  2010cited by this paper
• The Developmental Transcriptome of Drosophila melanogaster

  2010cited by this paper
• GPR30/GPER1: searching for a role in estrogen physiology.

  2009influential reference
• EGFR may couple moderate alcohol consumption to increased breast cancer risk.

  2009cited by this paper
• Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors.

  2009influential reference
• A protein kinase C activity localized to neuropeptide Y-like neurons mediates ethanol intoxication in Drosophila melanogaster.

  2008cited by this paper
• Efficient Ends-Out Gene Targeting In Drosophila

  2008cited by this paper
• A role for brain stress systems in addiction.

  2008cited by this paper
• Impact of the Hormonal Milieu on the Neurobiology of Alcohol Dependence and Withdrawal

  2006cited by this paper
• Recent developments in constitutive receptor activity and inverse agonism, and their potential for GPCR drug discovery.

  2006cited by this paper
• Rapid, Nongenomic Responses to Ecdysteroids and Catecholamines Mediated by a Novel Drosophila G-Protein-Coupled Receptor

  2005influential reference
• Spatiotemporal Gene Expression Targeting with the TARGET and Gene-Switch Systems in Drosophila

  2004cited by this paper
• Alcohol promotes dopamine release in the human nucleus accumbens

  2003cited by this paper
• Chronic ethanol exposure alters presynaptic dopamine function in the striatum of monkeys: A preliminary study

  2003cited by this paper
• Nongenomic actions of steroid hormones

  2003influential reference
• High-Resolution Analysis of Ethanol-Induced Locomotor Stimulation in Drosophila

  2002cited by this paper
• The 5-year clinical course of high-functioning men with DSM-IV alcohol abuse or dependence.

  2000cited by this paper
• Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila.

  2000influential reference
• Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway.

  1998cited by this paper
• Dopamine antagonist effects on locomotor activity in naive and ethanol-treated FAST and SLOW selected lines of mice

  1995cited by this paper
• Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

  1993cited by this paper
• Temperature-sensitive mutations in Drosophila melanogaster. XII. The genetic and developmental effects of dominant lethals on chromosome 3.

  1973cited by this paper

• Altered reactivity to threatening stimuli in Drosophila models of Parkinson’s disease, revealed by a trial-based assay

  2025cites this paper
• Ecdysteroid-DopEcR signaling in neuronal and midgut cells mediates toxin avoidance and detoxification in Drosophila.

  2025cites this paper
• Roles of a putative DopEcR‐like gene in temperature stress response and development of the oriental fruit fly, Bactrocera dorsalis

  2025cites this paper
• The GPCR A35 regulates fecundity of Nilaparvata lugens Stål via juvenile hormone signaling

  2025cites this paper
• From Natural Behavior to Drug Screening: Invertebrates as Models to Study Mechanisms Associated with Alcohol Use Disorders.

  2023cites this paper
• Corazonin Neurons Contribute to Dimorphic Ethanol Sedation Sensitivity in Drosophila melanogaster

  2022cites this paper
• Caffeine Delays Ethanol-Induced Sedation in Drosophila

  2022cites this paper
• Yeast volatiles double starvation survival in Drosophila

  2021cites this paper
• Cannabinoids differentially modulate behavioral and developmental responses to ethanol in Drosophila

  2021cites this paper
• Receptors and Channels Associated with Alcohol Use: Contributions from Drosophila

  2021cites this paper
• Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor

  2021cites this paper
• Voluntary intake of psychoactive substances is regulated by the dopamine receptor Dop1R1 in Drosophila

  2021cites this paper
• G-Protein Coupled Receptors (GPCRs): Signaling Pathways, Characterization, and Functions in Insect Physiology and Toxicology

  2021cites this paper
• G-Protein Coupled Receptors (GPCRs) in Insects—A Potential Target for New Insecticide Development

  2021cites this paper
• The Neurotransmitters Involved in Drosophila Alcohol-Induced Behaviors

  2020cites this paper
• Neurochemical Organization of the Drosophila Brain Visualized by Endogenously Tagged Neurotransmitter Receptors.

  2020cites this paper
• Significance of DopEcR, a G-protein coupled dopamine/ecdysteroid receptor, in physiological and behavioral response to stressors

  2020influential citation
• Anti-instinctive Learning Behavior Revealed by Locomotion-Triggered Mild Heat Stress in Drosophila

  2020cites this paper
• Extracellular matrix induced by steroids and aging through a G-protein-coupled receptor in a Drosophila model of renal fibrosis

  2020influential citation
• Flying Together: Drosophila as a Tool to Understand the Genetics of Human Alcoholism

  2020cites this paper
• G-protein αq gene expression plays a role in alcohol tolerance in Drosophila melanogaster

  2019cites this paper
• Extra-cellular matrix induced by steroids through a G-protein coupled receptor in a Drosophila model of renal fibrosis

  2019influential citation
• Calcitox-Metamorphosis in Insects: The Calcium (Ca2+)-Homeostasis System as the Integrated Primordial Receptor System for both Juvenile Hormone and Ecdysteroids1

  2019cites this paper
• A Fly’s Eye View of Natural and Drug Reward

  2018cites this paper
• Genetics and genomics of alcohol responses in Drosophila.

  2017influential citation
• Modulation of neuronal activity in the Drosophila mushroom body by DopEcR, a unique dual receptor for ecdysone and dopamine.

  2017cites this paper
• The Neuromodulatory Mechanisms That Monoamines Control Simple and Complex Behaviors

  2017cites this paper
• Ethanol binding sites on proteins.

  2017cites this paper
• Behavioral Sensitization to the Disinhibition Effect of Ethanol Requires the Dopamine/Ecdysone Receptor in Drosophila

  2017cites this paper
• The roles of a unique G-protein coupled dual receptor for dopamine and steroids in neuronal physiology and behavior

  2016cites this paper