Sex‐Based Differences in Coronary Physiological Assessment in Patients With Severe Aortic Stenosis

Assessing coronary artery disease in severe aortic stenosis (AS) presents unique challenges. Fractional flow reserve (FFR) may yield unreliable results due to altered coronary hemodynamics, leading to discordance with non‐hyperemic indices. Women with AS develop distinct myocardial remodeling patterns that may predispose to coronary microvascular dysfunction. We investigated whether sex influences the diagnostic performance and agreement of invasive physiological indices in severe AS.

• Publication year

  2025

• Venue

  Catheterization and cardiovascular interventions

• Publication date

  2025-11-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/ccd.70303PMID 41208186
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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