Transcriptomic Profiling of scWAT Reveals Reduced Lipid-Associated Macrophage Signatures in Long-Term Endurance- and Resistance-Trained Athletes

No abstract is available for this paper.

• Publication year

  2025

• Venue

  bioRxiv

• Publication date

  2025-11-08

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1101/2025.11.07.687158
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Exercise alters molecular profiles of inflammation and substrate metabolism in human white adipose tissue.

  2025cited by this paper
• iModulonMiner and PyModulon: Software for unsupervised mining of gene expression compendia

  2024cited by this paper
• Loss of adipose ATF3 promotes adipose tissue lipolysis and the development of MASH

  2024cited by this paper
• TM4SF19-mediated control of lysosomal activity in macrophages contributes to obesity-induced inflammation and metabolic dysfunction

  2024cited by this paper
• Conserved multi-tissue transcriptomic adaptations to exercise training in humans and mice

  2023cited by this paper
• Immune system adaptation during gender-affirming testosterone treatment

  2023cited by this paper
• Exercise-induced crosstalk between immune cells and adipocytes in humans: Role of oncostatin-M

  2023influential reference
• Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise – A systems biology approach

  2023cited by this paper
• Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training

  2023cited by this paper
• MRI characterization of skeletal muscle size and fatty infiltration in long‐term trained and untrained individuals

  2022cited by this paper
• Effect of Resistance Exercise on the Lipolysis Pathway in Obese Pre- and Postmenopausal Women

  2021cited by this paper
• Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2

  2021cited by this paper
• Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis

  2020cited by this paper
• iModulonDB: a knowledgebase of microbial transcriptional regulation derived from machine learning

  2020cited by this paper
• Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women.

  2020cited by this paper
• Baths

  2020cited by this paper
• MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations

  2020cited by this paper
• The impact of sex on gene expression across human tissues

  2020cited by this paper
• Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

  2019cited by this paper
• Molecular adaptations in human subcutaneous adipose tissue after ten weeks of endurance exercise training in healthy males.

  2019cited by this paper
• Tissue

  2019cited by this paper
• Adipocyte browning and resistance to obesity in mice is induced by expression of ATF3

  2019cited by this paper
• Determining cell-type abundance and expression from bulk tissues with digital cytometry

  2019cited by this paper
• Prediction of Adipose Browning Capacity by Systematic Integration of Transcriptional Profiles.

  2018cited by this paper
• Exercise training alters the genomic response to acute exercise in human adipose tissue

  2018cited by this paper
• Gender and Sex Differences in Adipose Tissue

  2018cited by this paper
• Exercise training-induced effects on the abdominal subcutaneous adipose tissue phenotype in humans with obesity.

  2018cited by this paper
• Exercise Induces White Adipose Tissue Browning Across the Weight Spectrum in Humans

  2018cited by this paper
• Aerobic exercise elevates markers of angiogenesis and macrophage IL-6 gene expression in the subcutaneous adipose tissue of overweight-to-obese adults.

  2017cited by this paper
• The landscape of sex-differential transcriptome and its consequent selection in human adults

  2017cited by this paper
• Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

  2016cited by this paper
• Fast gene set enrichment analysis

  2016influential reference
• Insulin-resistant subjects have normal angiogenic response to aerobic exercise training in skeletal muscle, but not in adipose tissue

  2015cited by this paper
• Sex differences in metabolic homeostasis, diabetes, and obesity

  2015cited by this paper
• Regulation of energy balance by inflammation: Common theme in physiology and pathology

  2015cited by this paper
• Quantifying size and number of adipocytes in adipose tissue.

  2014cited by this paper
• Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6‐month exercise intervention

  2014cited by this paper
• Coherent Functional Modules Improve Transcription Factor Target Identification, Cooperativity Prediction, and Disease Association

  2014cited by this paper
• The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis.

  2013cited by this paper
• ATF3 plays a role in adipocyte hypoxia-mediated mitochondria dysfunction in obesity.

  2013cited by this paper
• The Genotype-Tissue Expression (GTEx) project

  2013cited by this paper
• ATF3 protects against atherosclerosis by suppressing 25-hydroxycholesterol–induced lipid body formation

  2012cited by this paper
• Increased lipolysis and altered lipid homeostasis protect γ-synuclein–null mutant mice from diet-induced obesity

  2012cited by this paper
• Scikit-learn: Machine Learning in Python

  2011cited by this paper
• EGFL6 is increasingly expressed in human obesity and promotes proliferation of adipose tissue-derived stromal vascular cells

  2010cited by this paper
• Independent component analysis: Mining microarray data for fundamental human gene expression modules

  2010cited by this paper
• Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men.

  2006cited by this paper
• Muscle cross-sectional area and voluntary force production characteristics in elite strength- and endurance-trained athletes and sprinters

  2006cited by this paper
• Fatty acid mobilization from adipose tissue during exercise.

  2003cited by this paper
• Gene Ontology: tool for the unification of biology

  2000cited by this paper
• A Density-Based Algorithm for Discovering Clusters in Large Spatial Databases with Noise

  1996cited by this paper
• Positional cloning of the mouse obese gene and its human homologue

  1995cited by this paper
• Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance.

  1993cited by this paper
• The effect of a 20-week endurance training program on adipose-tissue morphology and lipolysis in men and women.

  1984cited by this paper
• Maximal oxygen uptake in athletes.

  1967cited by this paper

• No citing papers are available for this paper.