Pediatric psoriasis-associated comorbidities: beyond metabolic syndrome.

M. Buethe,Mira Choi,Nicola Natsis,L. Eichenfield

Published 2025 in Italian journal of dermatology and venereology

ABSTRACT

Pediatric psoriasis is a chronic inflammatory skin disorder which impacts lifetime health and is associated with potentially long-lasting morbidities. While the association between psoriasis and metabolic syndrome has been extensively studied, including in children, a comprehensive understanding of other comorbidities in the pediatric population remains limited. This paper aims to provide an updated review of pediatric psoriasis-associated comorbidities, extending beyond the scope of metabolic syndrome. The primary objective of this review is to elucidate the diverse spectrum of comorbidities linked to pediatric psoriasis, highlighting emerging research and identifying gaps in current knowledge. The multifaceted nature of pediatric psoriasis-associated comorbidities rationalizes a holistic approach for clinical management. The identified gaps in current knowledge warrant further investigation to enhance our understanding of the relationships between pediatric psoriasis and associated health outcomes.

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