Distinguishing Myo‐Inositol From Glycine in Brain MRS at 3T: A Pitfall Using Intermediate Echo Times

Ş. Alçiçek,G. Oeltzschner,Doris D. M. Lin,Peter B. Barker

Published 2025 in Journal of Neuroimaging

ABSTRACT

In in vivo magnetic resonance spectroscopy (MRS) of the brain, glycine (Gly) is traditionally separated from the overlapping signal of myo‐inositol (mI) through the use of intermediate (e.g., 130–140 ms) or long (270–280 ms) echo times (TE). However, no quantitative comparisons have been performed to date comparing the performance of clinically available MRS sequences to differentiate mI and Gly as a function of TE.

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