Incidence and Short‐Term Prognosis of Acute‐On‐Chronic Liver Failure Defined by Japanese Criteria: A Single‐Center Retrospective Cohort Study From Urban Japan

Acute‐on‐chronic liver failure (ACLF) carries high short‐term mortality, but real‐world evidence under the Japanese ACLF criteria remains limited. We assessed incidence, clinical profile, outcomes, and prognostic factors at a tertiary center in urban Japan.

• Publication year

  2025

• Venue

  JGH Open

• Publication date

  2025-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/jgh3.70300PMID 41229530PMCID 12602991
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Erratum to "EASL Clinical Practice Guidelines on acute-on-chronic liver failure" [J Hepatol 79 (2023) 461-491].

  2024cited by this paper
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  2022influential reference
• Nationwide survey for patients with acute-on-chronic liver failure occurring between 2017 and 2019 and diagnosed according to proposed Japanese criteria

  2021influential reference
• A multicenter pilot survey to clarify the clinical features of patients with acute‐on‐chronic liver failure in Japan

  2018cited by this paper
• Proposed diagnostic criteria for acute‐on‐chronic liver failure in Japan

  2018influential reference
• Acute-on-chronic liver failure.

  2015cited by this paper
• Clinical Course of acute‐on‐chronic liver failure syndrome and effects on prognosis

  2015influential reference
• Significance of pretransplant abstinence on harmful alcohol relapse after liver transplantation for alcoholic cirrhosis in Japan

  2014cited by this paper
• Toward an improved definition of acute-on-chronic liver failure.

  2014cited by this paper
• Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis.

  2013cited by this paper
• A systematic review on prognostic indicators of acute on chronic liver failure and their predictive value for mortality

  2013cited by this paper
• Acute-on chronic liver failure.

  2012cited by this paper
• Diagnostic criteria of acute liver failure: A report by the Intractable Hepato‐Biliary Diseases Study Group of Japan

  2011cited by this paper
• Acute-on-chronic liver failure: concept, natural history, and prognosis

  2011cited by this paper
• Clinical course of alcoholic liver cirrhosis: A Danish population‐based cohort study

  2010cited by this paper
• Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014

  2009cited by this paper
• Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)

  2009cited by this paper
• Hyponatremia and mortality among patients on the liver-transplant waiting list.

  2008influential reference
• Acute-on-Chronic Liver Failure: Pathophysiological Basis of Therapeutic Options

  2002cited by this paper

• No citing papers are available for this paper.