Unraveling the Extraction, Structure, Bioactivities, and Structure-Activity Relationship of Salvia miltiorrhiza Polysaccharides: A Review.

Salvia miltiorrhiza, a widely recognized traditional medicinal plant, is not only extensively used in clinical settings but also increasingly valued for its potential as a functional food ingredient. S. miltiorrhiza polysaccharides (SMPs), as the primary active components of S. miltiorrhiza, demonstrate excellent performance in antioxidant, hepatoprotective, and immunomodulatory effects. These attributes facilitate their advancement in nutritional health products, dietary supplements, and health-enhancing functional foods. Combining therapeutic and nutritional value, SMPs serve as a vital bridge connecting traditional medicine with modern functional food applications. This work offers a systematic assessment of the procedures for the extraction and purification of SMP, along with its structural features, biological activities, uses, and structure-activity connections. This framework is anticipated to establish a theoretical basis for subsequent research, applications, and progress in human health and product development.

• Publication year

  2025

• Venue

  Journal of Agricultural and Food Chemistry

• Publication date

  2025-11-12

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/acs.jafc.5c10285PMID 41222502
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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