SCIENCE@home

Examining diurnal cortisol changes as a pathway linking childhood adversity to depressive symptoms during adolescence.

Tamara Lorenz,Nathalie Michels,Matteo Giletta

Published 2025 in Development and Psychopathology

ABSTRACT

This study examined whether childhood adversity, specifically threat-related adversity, was associated with within-person changes in the cortisol awakening response (CAR) and diurnal cortisol slope (DCS), and whether these changes predicted increased depressive symptoms during adolescence. We also explored sex differences. In total, 283 first-year secondary school students in Belgium (M = 12.48 years; SD = 0.39; 42.8% female) participated in six assessments over 2.5 years. Childhood adversity (psychological, physical, and sexual victimization) reported at the first three waves was averaged. CAR and DCS latent residual change scores were derived from salivary cortisol samples collected during waves 1 and 3. Depressive symptom changes were assessed in linear growth curve models using self-reports from waves 3 to 6. The childhood adversity × sex interaction significantly predicted CAR and DCS changes, indicating a blunted CAR across waves for victimized boys, and a blunted DCS for victimized girls. Childhood adversity predicted the depressive symptoms intercept. No other predictors were associated with the depressive symptoms intercept, and none were linked to the depressive symptoms slope. Thus, childhood adversity may be linked to changes in diurnal cortisol patterns that differ by sex. Evidence for diurnal cortisol changes as a pathway to increased depressive symptoms remains inconclusive.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-69 of 69 references · Page 1 of 1

CITED BY