Selective detection of bacteria in urine with a long-range surface plasmon waveguide biosensor.

Experimentation demonstrates long-range surface plasmon polariton waveguides as a useful biosensor to selectively detect gram negative or gram positive bacteria in human urine having a low concentration of constituents. The biosensor can detect bacteria at concentrations of 10(5) CFU/ml, the internationally recommended threshold for diagnostic of urinary tract infection. Using a negative control urine solution of bacterial concentration 1000☓ higher than the targeted bacteria, we obtain a ratio of 5.4 for the positive to negative signals.

• Publication year

  2015

• Venue

  Biomedical Optics Express

• Publication date

  2015-08-01

• Fields of study

  Medicine, Chemistry, Engineering

• Identifiers
  DOI 10.1364/BOE.6.002908PMID 26309755PMCID PMC4541519
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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