Bioactive glass nanoparticles induce pronounced cytotoxicity in human hepatocellular carcinoma Hep-G2 cells through ROS-mediated genomic instability and mitochondrial apoptosis.

No abstract is available for this paper.

• Publication year

  2025

• Venue

  Naunyn-Schmiedeberg's Archives of Pharmacology

• Publication date

  2025-11-12

• Fields of study

  Medicine, Materials Science, Environmental Science

• Identifiers
  DOI 10.1007/s00210-025-04731-6PMID 41224953
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Y2O3NPs induce selective cytotoxicity, genomic instability, oxidative stress and ROS mediated mitochondrial apoptosis in human epidermoid skin A-431 Cancer cells

  2025cited by this paper
• Bioactive Glasses: Advancing Skin Tissue Repair through Multifunctional Mechanisms and Innovations

  2025cited by this paper
• Erbium oxide nanoparticles induce potent cell death, genomic instability and ROS-mitochondrial dysfunction-mediated apoptosis in U937 lymphoma cells

  2025cited by this paper
• Vitamin K1 attenuates acetaminophen-induced ferroptotic hepatic damage in mice via targeting keap1/Nrf2/HO-1 pathway

  2025cited by this paper
• Calcium titanate nanoparticles-induced cytotoxicity, genotoxicity and oxidative stress in human non-small lung cancer cells

  2025cited by this paper
• Electrophoretic Deposition of Bioactive Glass Coatings for Bone Implant Applications: A Review

  2024cited by this paper
• Yttrium oxide nanoparticles ameliorates calcium hydroxide and calcium titanate nanoparticles induced genomic DNA and mitochondrial damage, ROS generation and inflammation

  2024cited by this paper
• Spray-dried ternary bioactive glass microspheres: direct and indirect structural effects of copper-doping on acellular degradation behavior.

  2024cited by this paper
• In vitro cytotoxicity of magnetic-fluorescent bioactive glasses on SaOS-2, MC3T3-E1, BJ fibroblast cells, their hemolytic activity, and sorafenib release behavior.

  2024cited by this paper
• Acute Promyelocytic Leukemia: Review of Complications Related to All-Trans Retinoic Acid and Arsenic Trioxide Therapy

  2024cited by this paper
• Latest advances in hepatocellular carcinoma management and prevention through advanced technologies

  2024cited by this paper
• Current status and new directions for hepatocellular carcinoma diagnosis

  2024cited by this paper
• Mechanisms of ferroptotic and non-ferroptotic organ toxicity of chemotherapy: protective and therapeutic effects of ginger, 6-gingerol and zingerone in preclinical studies

  2024cited by this paper
• Multifunctional bioactive glass nanoparticles: surface–interface decoration and biomedical applications

  2024cited by this paper
• Systemic Therapy for Advanced Hepatocellular Carcinoma: Current Stand and Perspectives

  2023cited by this paper
• Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

  2023cited by this paper
• Advanced Bioactive Glasses: The Newest Achievements and Breakthroughs in the Area

  2023cited by this paper
• Recent Advances in Nanomaterials-Based Targeted Drug Delivery for Preclinical Cancer Diagnosis and Therapeutics

  2023cited by this paper
• Bioactive glass selectively promotes cytotoxicity towards giant cell tumor of bone derived neoplastic stromal cells and induces MAPK signalling dependent autophagy

  2022cited by this paper
• Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer

  2022cited by this paper
• Nanoparticle size distribution quantification from transmission electron microscopy (TEM) of ruthenium tetroxide stained polymeric nanoparticles.

  2021cited by this paper
• Bioactive Glass Applications: A Literature Review of Human Clinical Trials

  2021cited by this paper
• Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

  2021cited by this paper
• Addressing the worldwide hepatocellular carcinoma: epidemiology, prevention and management.

  2020cited by this paper
• Artemisinin induces selective and potent anticancer effects in drug resistant breast cancer cells by inducing cellular apoptosis and autophagy and G2/M cell cycle arrest.

  2020cited by this paper
• Bioactive Glass Nanoparticles for Tissue Regeneration

  2020cited by this paper
• New thiobarbituric acid scaffold‐based small molecules: Synthesis, cytotoxicity, 2D‐QSAR, pharmacophore modelling and in‐silico ADME screening

  2019cited by this paper
• Hepatocellular Carcinoma.

  2019cited by this paper
• Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems

  2018cited by this paper
• Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

  2018cited by this paper
• Systemic therapy for intermediate and advanced hepatocellular carcinoma: Sorafenib and beyond.

  2018cited by this paper
• Bioactive glass-based materials with hierarchical porosity for medical applications: Review of recent advances.

  2016cited by this paper
• A facile synthesis of novel mesoporous bioactive glass nanoparticles with various morphologies and tunable mesostructure by sacrificial liquid template method

  2015cited by this paper
• The comet assay: past, present, and future

  2015cited by this paper
• Sorafenib in advanced hepatocellular carcinoma: current status and future perspectives

  2014cited by this paper
• Mitochondrial NADH dehydrogenase polymorphisms are associated with breast cancer in Poland

  2014cited by this paper
• Epidemiology of hepatocellular carcinoma in the United States: Where are we? Where do we go?

  2014cited by this paper
• Review of bioactive glass: from Hench to hybrids.

  2013cited by this paper
• Aciculatin Induces p53-Dependent Apoptosis via MDM2 Depletion in Human Cancer Cells In Vitro and In Vivo

  2012cited by this paper
• Oxidative stress and oxidative damage in chemical carcinogenesis.

  2011cited by this paper
• Bioactive glass in tissue engineering.

  2011cited by this paper
• A review of the biological response to ionic dissolution products from bioactive glasses and glass-ceramics.

  2011cited by this paper
• Possible involvement of oxidative stress in potassium bromate-induced genotoxicity in human HepG2 cells.

  2011cited by this paper
• Protective potential of trans-resveratrol against 4-hydroxynonenal induced damage in PC12 cells.

  2010cited by this paper
• Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

  2009cited by this paper
• The DNA-damage response in human biology and disease

  2009cited by this paper
• p53 in health and disease

  2007cited by this paper
• Apoptosis: A Review of Programmed Cell Death

  2007cited by this paper
• Toxic Potential of Materials at the Nanolevel

  2006cited by this paper
• The comet assay for DNA damage and repair

  2004cited by this paper
• The Pathophysiology of Mitochondrial Cell Death

  2004cited by this paper
• The Bcl2 family: regulators of the cellular life-or-death switch

  2002cited by this paper
• Third-Generation Biomedical Materials

  2002cited by this paper
• Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

  2000cited by this paper
• A simple method for accurate estimation of apoptotic cells.

  2000cited by this paper
• Drug-induced apoptosis and p53, BCL-2 and BAX expression in breast cancer tissues in vivo and in fibroblast cells in vitro.

  1999cited by this paper
• Hepatocellular carcinoma

  1998cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper

• No citing papers are available for this paper.