Human immunodeficiency virus infection of helper T cell clones. Early proliferative defects despite intact antigen-specific recognition and interleukin 4 secretion.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Journal of Clinical Investigation

• Publication date

  1989-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI114090PMID 2470786PMCID PMC303904
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1988influential reference
• Lymphocyte activation by HIV-1 envelope glycoprotein

  1988cited by this paper
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• The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

  1988influential reference
• Human immunodeficiency virus (HIV-1) cytotoxicity: perturbation of the cell membrane and depression of phospholipid synthesis.

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  1987influential reference
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