Efecto de los antirretrovirales en la función renal de las personas en uso de la profilaxis previa a la exposición al VIH

Objetivo: evaluar el efecto de los antirretrovirales en la función renal de las personas en uso de la profilaxis previa a la exposición al VIH. Método: delineamiento descriptivo tipo encuesta longitudinal, realizado en la cohorte retrospectiva por 48 semanas. La muestra fue de 203 participantes. El muestreo fue no probabilístico por conveniencia. Se analizaron variables sociodemográficas, clínicas y de laboratorio. Se utilizó frecuencia absoluta, relativa, media, desviación estándar, mínima y máxima, prueba exacta de Fisher, prueba de Friedman, nivel de significancia <5%. Resultados: predominantemente hombres cis (86,2%), color de piel blanca (69,1%), alta escolaridad (76,7%) y edad media de ± 34 años. La presencia de marcadores de daño renal fue baja. La proteinuria tuvo un aumento hasta la semana 12 (2,6%), manteniendo una pequeña variación hasta la semana 48. La disminución de la estimación de la Tasa de Filtración Glomerular (eTFG) ≥25% en relación con los niveles basales fue de 4,4%, 3%, 4,4% y 3% en las semanas 12, 24, 36 y 48 respectivamente. No hubo asociación significativa entre la disminución de la eTFG ≥25% y la presencia de uno de los marcadores de daño renal. Conclusión: se ratifica la baja incidencia de eventos que caracterizan disfunción renal, como la disminución de la eTFG ≥25% y la presencia de eventos leves y aislados de proteinuria, glucosuria, uricosuria y cilindruria en 48 semanas de seguimiento.

• Publication year

  2025

• Venue

  Revista Latino-Americana de Enfermagem

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1590/1518-8345.7280.4733
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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