Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Cancer Discovery

• Publication date

  2011-08-25

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1158/2159-8290.CD-11-0080PMID 22586632PMCID PMC3919666
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• C-reactive protein and risk of lung cancer.

  2010cited by this paper
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• Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.

  2010influential reference
• Association of Nonsteroidal Anti-Inflammatory Drugs with Lung Cancer: Results from a Large Cohort Study

  2009cited by this paper
• Genomic Profiles Associated with Early Micrometastasis in Lung Cancer: Relevance of 4q Deletion

  2009cited by this paper
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  2009cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007influential reference
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  2007cited by this paper
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• [International HapMap project].

  2005cited by this paper
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  1994cited by this paper
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  1988cited by this paper
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  1979cited by this paper

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