Molecular characterization of a two-domain form of the neuronal voltage-gated P/Q-type calcium channel alpha(1)2.1 subunit.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  FEBS Letters

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12482583
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification and Characterization of Novel Human Cav2.2 (α1B) Calcium Channel Variants Lacking the Synaptic Protein Interaction Site

  2002cited by this paper
• Ca(2+)-independent but voltage-dependent secretion in mammalian dorsal root ganglion neurons.

  2002cited by this paper
• Intramembrane charge movements and excitation– contraction coupling expressed by two-domain fragments of the Ca2+ channel

  2001cited by this paper
• Molecular interaction of dihydropyridine receptors with type-1 ryanodine receptors in rat brain.

  2001cited by this paper
• Alternative Splicing in Intracellular Loop Connecting Domains II and III of the α1 Subunit of Cav1.2 Ca2+ Channels Predicts Two-domain Polypeptides with Unique C-terminal Tails*

  2001cited by this paper
• Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity

  2001cited by this paper
• The maternal transcript for truncated voltage-dependent Ca2+ channels in the ascidian embryo: a potential suppressive role in Ca2+ channel expression.

  2001cited by this paper
• Excitation–contraction coupling is unaffected by drastic alteration of the sequence surrounding residues L720–L764 of the α1S II-III loop

  2001cited by this paper
• Oxytocin retrogradely inhibits evoked, but not miniature, EPSCs in the rat supraoptic nucleus: role of N‐ and P/Q‐type calcium channels

  2001cited by this paper
• Biochemical and Biophysical Evidence for γ2 Subunit Association with Neuronal Voltage-activated Ca2+Channels*

  2001cited by this paper
• Dominant-Negative Synthesis Suppression of Voltage-Gated Calcium Channel Cav2.2 Induced by Truncated Constructs

  2001cited by this paper
• The I-II loop of the Ca2+ channel alpha1 subunit contains an endoplasmic reticulum retention signal antagonized by the beta subunit.

  2000cited by this paper
• Identification and cellular localisation of voltage-operated calcium channels in immature rat testis.

  2000cited by this paper
• A family of gamma-like calcium channel subunits.

  2000cited by this paper
• Structure and regulation of voltage-gated Ca2+ channels.

  2000cited by this paper
• Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels.

  2000cited by this paper
• High prevalence of CACNA1A truncations and broader clinical spectrum in episodic ataxia type 2

  1999cited by this paper
• Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.

  1999cited by this paper
• Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit.

  1999cited by this paper
• Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit.

  1999cited by this paper
• Interaction of Cysteine String Proteins with the α1A Subunit of the P/Q-type Calcium Channel*

  1998cited by this paper
• Tagging with green fluorescent protein reveals a distinct subcellular distribution of L-type and non-L-type Ca2+ channels expressed in dysgenic myotubes.

  1998cited by this paper
• RNA editing in the Drosophila DMCA1A calcium-channel alpha 1 subunit transcript.

  1998cited by this paper
• Evidence for a 95 kDa short form of the alpha1A subunit associated with the omega-conotoxin MVIIC receptor of the P/Q-type Ca2+ channels.

  1998cited by this paper
• The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit.

  1998cited by this paper
• Suppression of Slow Delayed Rectifier Current by a Truncated Isoform of KvLQT1 Cloned from Normal Human Heart*

  1997cited by this paper
• Alternative Splicing of the Sodium Channel SCN8A Predicts a Truncated Two-domain Protein in Fetal Brain and Non-neuronal Cells*

  1997cited by this paper
• Direct interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the α1A subunit of the P/Q‐type calcium channel

  1997cited by this paper
• Extracellular interaction of the voltage-dependent Ca2+ channel alpha2delta and alpha1 subunits.

  1997cited by this paper
• β Subunit Heterogeneity in Neuronal L-type Ca2+Channels*

  1997cited by this paper
• Structural and functional diversity of voltage-activated calcium channels.

  1996cited by this paper
• Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25.

  1996cited by this paper
• Identification of Three Subunits of the High Affinity ω-Conotoxin MVIIC-sensitive Ca2+ Channel*

  1996cited by this paper
• Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit.

  1994cited by this paper
• Ca2+ channel regulation by a conserved beta subunit domain.

  1994cited by this paper
• Roles of N-type and Q-type Ca2+ channels in supporting hippocampal synaptic transmission.

  1994cited by this paper
• Subunit identification and reconstitution of the N-type Ca2+ channel complex purified from brain.

  1993cited by this paper
• P-type voltage-dependent calcium channel mediates presynaptic calcium influx and transmitter release in mammalian synapses.

  1992cited by this paper
• A two-motif isoform of the major calcium channel subunit in skeletal muscle.

  1992cited by this paper
• Distinct calcium channels are generated by alternative splicing and are differentially expressed in the mammalian CNS.

  1991cited by this paper
• Primary structure of the gamma subunit of the DHP-sensitive calcium channel from skeletal muscle.

  1990cited by this paper
• Subunits of purified calcium channels: a 212-kDa form of alpha 1 and partial amino acid sequence of a phosphorylation site of an independent beta subunit.

  1989cited by this paper
• Restoration of excitation—contraction coupling and slow calcium current in dysgenic muscle by dihydropyridine receptor complementary DNA

  1988cited by this paper
• Structural characterization of the 1,4-dihydropyridine receptor of the voltage-dependent Ca2+ channel from rabbit skeletal muscle. Evidence for two distinct high molecular weight subunits.

  1987cited by this paper

• The life cycle of voltage-gated Ca2+ channels in neurons: an update on the trafficking of neuronal calcium channels

  2021cites this paper
• A CaV2.1 N-terminal fragment relieves the dominant-negative inhibition by an Episodic ataxia 2 mutant

  2016cites this paper
• Voltage sensor of ion channels and enzymes

  2011cites this paper
• MOLECULAR MECHANISMS OF Ca V 2.2 CALCIUM CHANNEL REGULATION

  2011cites this paper
• Alternative Splicing in the Synaptic Protein Interaction Site of Rat Cav2.2 (α1B) Calcium Channels: Changes Induced by Chronic Inflammatory Pain

  2009cites this paper
• Alpha-2-delta subunits of voltage-gated calcium channels

  2008cites this paper
• A Destructive Interaction Mechanism Accounts for Dominant-Negative Effects of Misfolded Mutants of Voltage-Gated Calcium Channels

  2008influential citation
• Dominant‐negative effects of episodic ataxia type 2 mutations involve disruption of membrane trafficking of human P/Q‐type Ca2+ channels

  2008cites this paper
• The P/Q‐type voltage‐dependent calcium channel: a therapeutic target in spinocerebellar ataxia type 6

  2007cites this paper
• Dominant-negative suppression of Cav2.1 currents by alpha(1)2.1 truncations requires the conserved interaction domain for beta subunits.

  2007influential citation
• [P/Q-type voltage-dependent calcium channels in neurological disease].

  2007cites this paper
• Voltage-dependent calcium channels in mammalian spermatozoa revisited.

  2007cites this paper
• The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit.

  2007cites this paper
• Dominant-negative effects of human P/Q-type Ca2+ channel mutations associated with episodic ataxia type 2.

  2006cites this paper
• Splicing for alternative structures of Cav1.2 Ca2+ channels in cardiac and smooth muscles.

  2005cites this paper
• Glycosylation of asparagines 136 and 184 is necessary for the alpha2delta subunit-mediated regulation of voltage-gated Ca2+ channels.

  2004cites this paper
• Dominant-Negative Calcium Channel Suppression by Truncated Constructs Involves a Kinase Implicated in the Unfolded Protein Response

  2004cites this paper
• The role of voltage gated T-type Ca2+ channel isoforms in mediating "capacitative" Ca2+ entry in cancer cells.

  2004cites this paper