EXPERIMENTAL GENERALIZED ANALGESIA AFTER EXPOSURE TO SOME WAR GASES

Cats gassed with dimethylsulfate or chloropicrin in such concentration that death generally results within 4 days, usually exhibit a marked generalized analgesia, both superficial and deep. Gassed cats react with no obvious sign of pain to operative interferences, including laparotomy and gentle friction of the parietal-peritoneum. The analgesia develops within a few hours after gassing, and reaches its maximum in about 24 hours. With dimethylsulfate the analgesia may persist for 6 months; with chloropicrin practically normal sensitiveness has been observed 7 days after gassing. This analgesia is considered to be caused and maintained largely by a general, low grade, tissue aspbyxia which is chiefly of pulmonic origin.

• Publication year

  1922

• Venue

  Journal of Experimental Medicine

• Publication date

  1922-01-31

• Fields of study

  Medicine

• Identifiers
  DOI 10.1084/JEM.35.2.97PMID 19868605PMCID 2128107
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

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