Evaluation of Artificial Intelligence for Patient Self-Triage: Comparison of General-Purpose AI Platforms With the NHS 111 Online Symptom Checker in the United Kingdom

Hannah Brown

Published 2025 in Cureus

ABSTRACT

Emergency departments (EDs) in the UK face substantial pressure due to non-urgent attendances. This technical report evaluates the performance of two general-purpose artificial intelligence (AI) platforms (ChatGPT GPT-5 (OpenAI, San Francisco, California, USA) and Gemini AI v2.5 Flash (Google, Mountain View, California, USA)) for patient self-triage, compared with the NHS 111 online symptom checker. Ten simulated patient scenarios, including five emergency and five non-emergency cases, were assessed against National Institute for Health and Care Excellence (NICE) guideline-based gold standards. Both AI platforms correctly identified all emergency cases; NHS 111 under-triaged one acute emergency. For non-emergency scenarios, AI occasionally over-triaged, recommending emergency assessment for pyelonephritis, whereas NHS 111 correctly classified all non-emergencies. AI triage responses were faster and required fewer follow-up questions than NHS 111, although sometimes producing unclear recommendations. The findings suggest that general-purpose AI may serve as an adjunct to NHS 111, supporting patient self-triage and potentially reducing ED burden. Future work should include larger-scale testing, real patient data, and prospective safety evaluation to assess clinical feasibility.

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