Activation of Interferon-Stimulated Response Element in Huh-7 Cells Replicating Hepatitis C Virus Subgenomic RNA

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Intervirology

• Publication date

  2005-06-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1159/000085099PMID 15956798
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Interferons α, β, γ each inhibit hepatitis C virus replication at the level of internal ribosome entry site‐mediated translation

  2005cited by this paper
• Specific inhibition of hepatitis C virus replication by cyclosporin A

  2005cited by this paper
• Interferons alpha, beta, gamma each inhibit hepatitis C virus replication at the level of internal ribosome entry site-mediated translation.

  2005cited by this paper
• Interferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone.

  2004cited by this paper
• Specific inhibition of hepatitis C virus replication by cyclosporin A.

  2004cited by this paper
• Hepatitis C Virus Core Protein Differently Regulates the JAK-STAT Signaling Pathway under Interleukin-6 and Interferon-γ Stimuli*

  2003cited by this paper
• Management of hepatitis C.

  2003cited by this paper
• Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice.

  2003cited by this paper
• Gene Expression Profiling of the Cellular Transcriptional Network Regulated by Alpha/Beta Interferon and Its Partial Attenuation by the Hepatitis C Virus Nonstructural 5A Protein

  2003cited by this paper
• Differential activation of interferon-inducible genes by hepatitis C virus core protein mediated by the interferon stimulated response element.

  2003cited by this paper
• 3′ Nontranslated RNA Signals Required for Replication of Hepatitis C Virus RNA

  2003cited by this paper
• Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli.

  2003cited by this paper
• Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes

  2003cited by this paper
• Hepatitis C virus genetic variability: pathogenic and clinical implications.

  2003cited by this paper
• The nature of interferon-alpha resistance in hepatitis C virus infection.

  2003cited by this paper
• Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line

  2003cited by this paper
• Interferon‐γ inhibits replication of subgenomic and genomic hepatitis C virus RNAs

  2002cited by this paper
• Genetic Analysis of Sequences in the 3′ Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication

  2002cited by this paper
• Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome [Science 1989;244:359-362].

  2002cited by this paper
• [Epidemiology of hepatitis C].

  2002cited by this paper
• Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs.

  2002cited by this paper
• [Molecular virology of hepatitis C].

  2002cited by this paper
• Effect of Alpha Interferon on the Hepatitis C Virus Replicon

  2001cited by this paper
• Expression of hepatitis C virus NS5A natural mutants in a hepatocytic cell line inhibits the antiviral effect of interferon in a PKR‐independent manner

  2001cited by this paper
• Sequences in the 5′ Nontranslated Region of Hepatitis C Virus Required for RNA Replication

  2001cited by this paper
• How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A.

  2001cited by this paper
• Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures.

  2000cited by this paper
• Hepatocellular carcinoma: an emerging problem with hepatitis C.

  2000cited by this paper
• Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties.

  2000cited by this paper
• Role of the Intracellular Domain of the Human Type I Interferon Receptor 2 Chain (IFNAR2c) in Interferon Signaling

  2000cited by this paper
• Expression of Hepatitis C Virus Proteins Interferes with the Antiviral Action of Interferon Independently of PKR-Mediated Control of Protein Synthesis

  2000cited by this paper
• Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein.

  1999cited by this paper
• Current and evolving therapies for hepatitis C.

  1999cited by this paper
• Management of hepatitis C: current and future perspectives.

  1999cited by this paper
• Antiapoptotic and Oncogenic Potentials of Hepatitis C Virus Are Linked to Interferon Resistance by Viral Repression of the PKR Protein Kinase

  1999cited by this paper
• Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line.

  1999cited by this paper
• Replication of Subgenomic Hepatitis C Virus Rnas in a Hepatoma Cell Line

  1999cited by this paper
• Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response.

  1999cited by this paper
• STAT1 Is Inactivated by a Caspase*

  1998cited by this paper
• Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group.

  1998cited by this paper
• Epidemiology of hepatitis C

  1997cited by this paper
• The treatment of chronic viral hepatitis.

  1997cited by this paper
• National Institutes of Health Consensus Development Conference Panel statement: Management of hepatitis C

  1997cited by this paper
• The molecular virology of hepatitis C

  1997cited by this paper
• Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein.

  1997cited by this paper
• Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA

  1996cited by this paper
• Structure of the 3' terminus of the hepatitis C virus genome

  1996cited by this paper
• Treatment of chronic viral hepatitis.

  1994cited by this paper
• The beta-interferon promoter responds to priming through multiple independent regulatory elements.

  1994cited by this paper
• Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins.

  1994cited by this paper
• Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini

  1994cited by this paper
• Expression and identification of hepatitis C virus polyprotein cleavage products

  1993cited by this paper
• Cyclic AMP response element-binding protein and the catalytic subunit of protein kinase A are present in F9 embryonal carcinoma cells but are unable to activate the somatostatin promoter

  1992cited by this paper
• Secondary structure of the 5' nontranslated regions of hepatitis C virus and pestivirus genomic RNAs.

  1992cited by this paper
• Sequence analysis of the 5' noncoding region of hepatitis C virus.

  1992cited by this paper
• Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis.

  1991cited by this paper
• Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease

  1991cited by this paper
• Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups.

  1990cited by this paper
• Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome.

  1989cited by this paper
• Epidemiology of hepatitis.

  1965cited by this paper

• Hepatitis C virus control: viral resistance, new therapeutic targets and host defense

  2016cites this paper
• Cellular Mechanism for Impaired Hepatitis C Virus Clearance by Interferon Associated with IFNL3 Gene Polymorphisms Relates to Intrahepatic Interferon-λ Expression.

  2016cites this paper
• Functional analysis of replication determinantsin classical swine fever virus

  2016cites this paper
• Mechanism of HCV's resistance to IFN-α in cell culture involves expression of functional IFN-α receptor 1

  2011cites this paper
• Intracellular expression of IRF9 Stat fusion protein overcomes the defective Jak-Stat signaling and inhibits HCV RNA replication

  2010cites this paper
• Impaired antiviral activity of interferon alpha against hepatitis C virus 2a in Huh-7 cells with a defective Jak-Stat pathway

  2010cites this paper
• Quantitation of replication of the HCV genome in human livers with end‐stage cirrhosis by strand‐specific real‐time RT‐PCR assays: Methods and clinical relevance

  2009cites this paper
• Increased apoptosis in HepG2.2.15 cells with hepatitis B virus expression by synergistic induction of interferon‐γ and tumour necrosis factor‐α

  2009cites this paper
• Mechanisms of Interferon Action and Resistance in Chronic Hepatitis C Virus Infection: Lessons Learned from Cell Culture Studies

  2008cites this paper
• Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon

  2007cites this paper
• Novel Alpha Interferon (IFN-α) Variant with Improved Inhibitory Activity against Hepatitis C Virus Genotype 1 Replication Compared to IFN-α2b Therapy in a Subgenomic Replicon System

  2006cites this paper
• HCV‐hepatocellular carcinoma: New findings and hope for effective treatment

  2005cites this paper