Rosuvastatin attenuates mucus secretion in a murine model of chronic asthma by inhibiting the gamma-aminobutyric acid type A receptor.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Chinese Medical Journal

• Publication date

  2012-04-01

• Fields of study

  Medicine

• Identifiers
  PMID 22613653
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Airway mucus: the good, the bad, the sticky.

  2009cited by this paper
• Statins may reduce episodes of exacerbation and the requirement for intubation in patients with COPD: evidence from a retrospective cohort study

  2008cited by this paper
• CD4+CD25+ regulatory T cells reverse established allergic airway inflammation and prevent airway remodeling.

  2008cited by this paper
• Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma

  2008cited by this paper
• Statin use reduces decline in lung function: VA Normative Aging Study.

  2007cited by this paper
• Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model.

  2007cited by this paper
• A new link to airway obstruction in asthma

  2007cited by this paper
• Potential therapeutic role for statins in respiratory disease

  2006cited by this paper
• Respiratory tract mucin genes and mucin glycoproteins in health and disease.

  2006cited by this paper
• Statin therapy and autoimmune disease: from protein prenylation to immunomodulation

  2006cited by this paper
• Statin use is associated with reduced mortality in COPD

  2006cited by this paper
• Chlamydia Infection Induces ICOS Ligand-Expressing and IL-10-Producing Dendritic Cells That Can Inhibit Airway Inflammation and Mucus Overproduction Elicited by Allergen Challenge in BALB/c Mice1

  2006cited by this paper
• Effects of statins beyond lipid lowering: potential for clinical benefits.

  2006cited by this paper
• Pleiotropic effects of statins.

  2005cited by this paper
• Biomedicine. Eosinophils in asthma: remodeling a tangled tale.

  2004cited by this paper
• A Novel Anti-Inflammatory Role of Simvastatin in a Murine Model of Allergic Asthma1

  2004cited by this paper
• Difficult asthma

  2003cited by this paper
• Asthma: an epidemic of dysregulated immunity

  2002cited by this paper
• GABAergic Mechanisms in Epilepsy

  2001cited by this paper
• Similar Effects of Atorvastatin, Simvastatin and Pravastatin on Thrombogenic and Inflammatory Parameters in Patients with Hypercholesterolemia

  2001cited by this paper
• The Functional Role of Rho and Rho-Associated Coiled-Coil Forming Protein Kinase in Eotaxin Signaling of Eosinophils1

  2001cited by this paper
• Pravastatin Treatment Increases Collagen Content and Decreases Lipid Content, Inflammation, Metalloproteinases, and Cell Death in Human Carotid Plaques: Implications for Plaque Stabilization

  2001cited by this paper
• Simvastatin Has Anti-Inflammatory and Antiatherosclerotic Activities Independent of Plasma Cholesterol Lowering

  2000cited by this paper

• Dyslipidemia in asthma: Treatable trait, or just a common comorbidity?

  2025cites this paper
• Remimazolam mitigates oxidative stress response in patients undergoing one-lung ventilation

  2025cites this paper
• DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1

  2024cites this paper
• Rosuvastatin attenuates airway inflammation and remodeling in a chronic allergic asthma model through modulation of the AMPKα signaling pathway

  2024cites this paper
• Serum Metabolomics Reveals Metabolomic Profile and Potential Biomarkers in Asthma

  2024cites this paper
• Schisandrin A ameliorates airway inflammation in model of asthma by attenuating Th2 response.

  2023cites this paper
• Pathogenesis of ventilator-induced lung injury: metabolomics analysis of the lung and plasma

  2022cites this paper
• GLP-1 receptor agonist as a modulator of innate immunity

  2022cites this paper
• EGCG promotes PRKCA expression to alleviate LPS-induced acute lung injury and inflammatory response

  2021cites this paper
• Investigation of Pharmacological Mechanisms of Schisandrin a for the Treatment of Asthma Determined by Network Pharmacology and Experimental Validation

  2021cites this paper
• Anti-inflammatory and Antioxidant Effects of Rosuvastatin on Asthmatic, Hyperlipidemic, and Asthmatic-Hyperlipidemic Rat Models

  2021influential citation
• Atractylodin attenuates the expression of MUC5AC and extracellular matrix in lipopolysaccharide‐induced airway inflammation by inhibiting the NF‐κB pathway

  2021cites this paper
• Chinese Herbs and Repurposing Old Drugs as Therapeutic Agents in the Regulation of Oxidative Stress and Inflammation in Pulmonary Diseases

  2021cites this paper
• Monocyte chemotactic protein-inducing protein 1 negatively regulating asthmatic airway inflammation and mucus hypersecretion involving γ-aminobutyric acid type A receptor signaling pathway in vivo and in vitro

  2020cites this paper
• Rosuvastatin suppresses cytokine production and lung inflammation in asthmatic, hyperlipidemic and asthmatic-hyperlipidemic rat models.

  2020cites this paper
• Curcumin Attenuates Asthmatic Airway Inflammation and Mucus Hypersecretion Involving a PPARγ-Dependent NF-κB Signaling Pathway In Vivo and In Vitro

  2019cites this paper
• Rosuvastatin Affects Tracheal Responsiveness, Bronchoalveolar Lavage Inflammatory Cells, and Oxidative Stress Markers in Hyperlipidemic and Asthmatic Rats.

  2019cites this paper
• Fisetin-treatment alleviates airway inflammation through inhbition of MyD88/NF-κB signaling pathway

  2018cites this paper
• Prophylactic benefits of systemically delivered simvastatin treatment in a house dust mite challenged murine model of allergic asthma

  2018cites this paper
• GLP-1 Analogue Liraglutide Enhances SP-A Expression in LPS-Induced Acute Lung Injury through the TTF-1 Signaling Pathway

  2018cites this paper
• Potential Therapeutic Role of Rosuvastatin and Simvastatin in Acute Lung Injury ( Experimental Study )

  2017cites this paper
• Emodin suppresses LPS-induced inflammation in RAW264.7 cells through a PPARγ-dependent pathway.

  2016cites this paper
• Statins in Asthma: A Closer Look into the Pharmacological Mechanism of Action

  2016cites this paper
• Expanding the role of rosuvastatin as a pulmonary-protective agent.

  2016cites this paper
• Increase of Frequency and Modulation of Phenotype of Regulatory T Cells by Atorvastatin Is Associated with Decreased Lung Inflammatory Cell Infiltration in a Murine Model of Acute Allergic Asthma

  2016cites this paper
• Mevastatin ameliorates sphingosine 1‐phosphate‐induced COX‐2/PGE2‐dependent cell migration via FoxO1 and CREB phosphorylation and translocation

  2015cites this paper
• Novel Therapies to Inhibit Mucus Synthesis and Secretion in Airway Hypersecretory Diseases

  2015cites this paper
• Glucagon Like Peptide-1 (GLP-1) Modulates OVA-Induced Airway Inflammation and Mucus Secretion Involving a Protein Kinase A (PKA)-Dependent Nuclear Factor-κB (NF-κB) Signaling Pathway in Mice

  2015cites this paper
• Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents.

  2014cites this paper
• Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.

  2014cites this paper
• Glucagon like peptide-1 attenuates bleomycin-induced pulmonary fibrosis, involving the inactivation of NF-κB in mice.

  2014cites this paper
• Rosiglitazone, a peroxisome proliferator-activated receptor-γ agonist, attenuates airway inflammation by inhibiting the proliferation of effector T cells in a murine model of neutrophilic asthma.

  2014cites this paper
• Emodin Ameliorates LPS-Induced Acute Lung Injury, Involving the Inactivation of NF-κB in Mice

  2014cites this paper
• The Effect of Atorvastatin (Lipitor) on the Duration of Survival of Allogeneic Skin Graft and the Growth of B16F10 Melanoma Cells in Mice

  2013cites this paper
• Statins in the treatment of asthma.

  2013cites this paper
• Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.

  2013cites this paper
• The Effect of Atorvastatin ( Lipitor ) on the 3 Duration of Survival of Allogeneic Skin Graft 4 and the Growth of B 16 F 10 Mmelanoma Cells in 5 Mice

  2013cites this paper
• Protective Role of Andrographolide in Bleomycin-Induced Pulmonary Fibrosis in Mice

  2013cites this paper
• Gephyrin, the enigmatic organizer at GABAergic synapses

  2012cites this paper