Comparative distribution and embryotoxicity of acetylsalicylic acid in pregnant rats and rhesus monkeys.

No abstract is available for this paper.

• Publication year

  1977

• Venue

  Toxicology and Applied Pharmacology

• Publication date

  1977-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0041-008X(77)90054-0PMID 408942
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparative distribution and embryotoxicity of hydroxyurea in pregnant rats and rhesus monkeys.

  1975cited by this paper
• Associations between oral clefts and drugs taken during pregnancy.

  1975cited by this paper
• Gangrene of the Extremities in a Newborn Premature Infant

  1973cited by this paper
• The Possible Teratogenic Effect of Salicylates on the Developing Fetus

  1973cited by this paper
• Abnormalities of intrauterine development in non-human primates.

  1972cited by this paper
• A rapid method for the determination of salicylate binding by the use of ultrafilters

  1972cited by this paper
• Use of rhesus monkeys in teratological studies.

  1971cited by this paper
• Studies on metabolism and identification of the causative agent in aspirin teratogenesis in rats.

  1971cited by this paper
• Associations between Drugs Administered during Pregnancy and Congenital Abnormalities of the Fetus

  1971cited by this paper
• Use of rhesus monkeys in teratological studies.

  1971cited by this paper
• Teratogenic drugs--R.C.G.P. survey.

  1970cited by this paper
• Breeding and pregnancy in rhesus monkeys used for teratological testing.

  1970cited by this paper
• Congenital malformations and environmental influences in pregnancy.

  1969cited by this paper
• Salicylate‐Induced Fetal Death and Malformations in Two Mouse Strains

  1966cited by this paper
• SALICYLAMIDE-INDUCED ANOMALIES IN HAMSTER EMBRYOS.

  1964cited by this paper
• Letters to the EditorANTIBIOTICS AND CONGENITAL MALFORMATIONS

  1963cited by this paper
• Antibiotics and congenital malformations.

  1963cited by this paper
• Experimental production of congenital malformations in rats by salicylate poisoning.

  1959cited by this paper
• A simple fluorometric procedure for determining salicylic acid in biologic tissues.

  1959cited by this paper
• Toxic effects of salicylate on the fœtus and mother

  1948cited by this paper

• Synthetic and Biogenic Materials for Oral Delivery of Biologics: From Bench to Bedside.

  2025cites this paper
• Cross‐species signaling pathways analysis inspire animal model selections for drug screening and target prediction in vascular aging diseases

  2024cites this paper
• 3D bioprinting and the revolution in experimental cancer model systems—A review of developing new models and experiences with in vitro 3D bioprinted breast cancer tissue-mimetic structures

  2023cites this paper
• The road (not) taken - Placental transfer and interspecies differences.

  2021cites this paper
• Limitations of Animal Studies for Predicting Toxicity in Clinical Trials

  2019cites this paper
• ON salicylic acid ( CAS 69-727 ) Submission

  2019cites this paper
• A kinetic‐based safety assessment of consumer exposure to salicylic acid from cosmetic products demonstrates no evidence of a health risk from developmental toxicity

  2018cites this paper
• Guidelines for Reproductive Toxicity Risk Assessment

  2014cites this paper
• Guidelines for Developmental Toxicity Risk Assessment

  2014cites this paper
• Non-Narcotic Analgesics

  2012cites this paper
• Non-Narcotic Analgesics Use in Pregnancy and Fetal and Perinatal Effects

  2012cites this paper
• Animal Research in Medical Sciences: Seeking a Convergence of Science, Medicine, and Animal Law

  2012cites this paper
• Mapping progress in toxicology research by the content of the best papers published in Society of Toxicology Journals: a synopsis of the best paper awardees (1974-2011).

  2011cites this paper
• Clopidogrel treatment during pregnancy: a case report and a review of literature.

  2011cites this paper
• Effect of other drugs and chemicals on the degradation of aspirinin vitro: Possible extrapolation toin vivo metabolism of aspirin

  2010cites this paper
• The Developing Nervous System

  2010cites this paper
• Quantitative extrapolation of in vitro whole embryo culture embryotoxicity data to developmental toxicity in vivo using the benchmark dose approach.

  2008influential citation
• Quantitative in vitro - in vivo extrapolation

  2008cites this paper
• [Salazosulfapyridine in pregnancy?].

  2008cites this paper
• [Low dose of aspirin during pregnancy].

  2007cites this paper
• Modeling the effects of prenatal exposure to aspirin on the postnatal development of rat brain.

  2007cites this paper
• Krox20 is down-regulated following triazole in vitro embryonic exposure: a polycompetitor-based assay.

  2007cites this paper
• Ácido acetilsalicílico en dosis bajas durante el embarazo

  2007cites this paper
• Systematic Reviews of Animal Experiments Demonstrate Poor Human Clinical and Toxicological Utility

  2007cites this paper
• Analysis of reproductive toxicity and classification of glufosinate-ammonium.

  2006cites this paper
• Allometry of Postnatal Rat Brain Development Prenatally Exposed to Aspirin

  2006cites this paper
• The future of teratology research is in vitro

  2005cites this paper
• Evaluating Chemical and other Agent Exosures for Reproductive and Developmental Toxicity

  2004cites this paper
• Analysis of the nonsteroidal anti-inflammatory drug literature for potential developmental toxicity in rats and rabbits.

  2003cites this paper
• Drugs in Pregnancy

  2002cites this paper
• A population‐based case–control teratologic study of acetylsalicylic acid treatments during pregnancy

  2000cites this paper
• Chapter 16 – PB/PK Models

  1998cites this paper
• Drugs in pregnancy.

  1998cites this paper
• A risk assessment of topical tretinoin as a potential human developmental toxin based on animal and comparative human data.

  1997cites this paper
• Intracellular pH monkey embryos at various stages of organogenesis estimated by dimethadione distribution.

  1996cites this paper
• Interlaboratory evaluation of embryotoxicity in the postimplantation rat embryo culture.

  1995cites this paper
• In Vitro Developmental Toxicity of Aspirin and Its Major Metabolites on Cultured Fetal Mouse Palates

  1995cites this paper
• An evaluative process for assessing human reproductive and developmental toxicity of agents.

  1995cites this paper
• Pregnancy, drugs, and the dermatologist

  1994cites this paper
• Influence of Protein Malnutrition on Teratogenicity of Acetylsalicylic Acid in Rats

  1994cites this paper
• Differences in NSAID Tolerability Profiles

  1994cites this paper
• The genetic toxicology of paracetamol and aspirin: a review.

  1993cites this paper
• Pharmacokinetics and drug metabolism in the design and interpretation of developmental toxicity studies

  1992cites this paper
• Embryonal disposition of salicylate: in vivo-in vitro comparisons.

  1990cites this paper
• Fetal alcohol syndrome: current status of pathogenesis.

  1990cites this paper
• Proposals for improving risk assessment in reproductive toxicology.

  1990cites this paper
• Nonhuman primates and teratological research.

  1990cites this paper
• Effects of dietary sodium selenite supplementation on salicylate-induced embryo- and fetotoxicity in the rat.

  1990cites this paper
• The risks and benefits of taking aspirin during pregnancy.

  1990cites this paper
• Aspirin augments alcohol in restricting brain growth in the neonatal rat.

  1989cites this paper
• Teratologic potential of 2-methoxyethanol and transplacental distribution of its metabolite, 2-methoxyacetic acid, in non-human primates.

  1989cites this paper
• Embryo-maternal distribution of basic compounds in the CD-1 mouse: doxylamine and nicotine.

  1989cites this paper
• Developmental Toxicity of Aspirin Prenatally Given to Rats: Assessment in Slc: Wistar‐KY Rats

  1988cites this paper
• Detection of neuroteratogens with an in vitro cytotoxicity assay using primary monolayers cultured from dissociated foetal rat brains.

  1988cites this paper
• Disposition and metabolism of [14C]-amezinium metilsulfate in rats.

  1988cites this paper
• [Drug prescriptions in pregnancy. Current status].

  1988cites this paper
• Developmental Toxicity of Aspirin Prenatally Given to Rats: Assessment in Sic: Wistar‐KY Rats

  1988cites this paper
• ArzneimittelVerordnung während der Schwangerschaft

  1988cites this paper
• Effect of indomethacin on alcohol-induced morphological anomalies in mice.

  1987cites this paper
• The role of metabolism in the testing of developmental toxicants.

  1987cites this paper
• A method to obtain maternal-fetal plasma samples using a microsampling technique in the rat: transplacental passage of cefoxitin.

  1987cites this paper
• Routine teratogenicity test that uses chick embryos in vitro.

  1987cites this paper
• Evaluation of the teratogenicity and pharmacokinetics of diflunisal in cynomolgus monkeys.

  1987cites this paper
• Interagency regulatory liaison group workshop on reproductive toxicity risk assessment.

  1986cites this paper
• Species differences in pharmacokinetics and drug teratogenesis.

  1986cites this paper
• In vitro teratogenicity of acetylsalicylic acid on rat embryos: studies with various culture conditions.

  1986cites this paper
• Teratogenic effects on the CD-1 mouse embryo exposed to concurrent doses of ethanol and aspirin.

  1986cites this paper
• Biophysical study of bioactive-substance conformation and interaction with drugs in solution

  1985cites this paper
• Diflunisal-induced maternal anemia as a cause of teratogenicity in rabbits.

  1984cites this paper
• Embryotoxic effects of salicylates: role of biotransformation.

  1984cites this paper
• Issues and Reviews in Teratology

  1984cites this paper
• Prostaglandin synthesis in rat embryo tissue: the effect of non-steroidal anti-inflammatory drugs in vivo and ex vivo.

  1984cites this paper
• Adverse Effects in Humans and Animals of Prenatal Exposure to Selected Therapeutic Drugs and Estimation of Embryo-Fetal Sensitivity of Animals for Human Risk Assessment

  1984cites this paper
• Acetylation of Nucleosides by Acetylsalicylic Acid (Aspirin)1

  1983cites this paper
• Developmental Toxicity and Nonhuman Primates

  1983cites this paper
• A selection of candidate compounds for in vitro teratogenesis test validation.

  1983cites this paper
• Studies on the pharmacological bases of fetal toxicity of drugs (IV). Effect of endotoxin and starvation on serum protein binding of salicylic acid in pregnant rats.

  1983cites this paper
• Correlating pharmacokinetics and teratogenic endpoints.

  1983cites this paper
• Peripheral hypotensive and central hypertensive effects of cimetidine

  1982cites this paper
• Species Variation in Evaluation of Safety of Drugs in the Developing Animal

  1982cites this paper
• Influence of a low protein diet on salicylate-induced damage in mice.

  1982cites this paper
• Placental transfer and fetal uptake of drugs.

  1982cites this paper
• Indomethacin--placental transfer, cytotoxicity, and teratology in the rat.

  1981cites this paper
• [Azulfidine/Salazopyrin therapy during pregnancy].

  1981cites this paper
• Aspirin: teratogenic evaluation in the dog.

  1979cites this paper
• Comparative distribution and embryotoxicity of methotrexate in pregnant rats and rhesus monkeys.

  1979cites this paper
• Primate teratology: selection of species and future use

  1979cites this paper
• Utility of pharmacokinetics in designing toxicological protocols and improving interspecies extrapolation.

  1978cites this paper
• Analytical Techniques for the Study of Teratogenic Mechanisms

  1978cites this paper
• Feasibility and Design of Subhuman Primate Studies

  1978cites this paper