Use of oral miltefosine for cutaneous leishmaniasis in Canadian soldiers returning from Afghanistan.

Y. Keynan,O. Larios,M. Wiseman,Marie Plourde,M. Ouellette,E. Rubinstein

Published 2008 in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

ABSTRACT

Old world cutaneous leishmaniasis (CL) is caused by Leishmania major and Leishmania tropica, and is endemic to several Asian and Middle-Eastern countries where the rates of infection can be substantial. CL is one of the most common vector-transmitted parasitic infections in Afghanistan. Six cases of CL in Canadian soldiers returning from Afghanistan are reported in the present study. Their lesions did not improve with fluconazole therapy, and the organism demonstrated in vitro resistance. Oral miltefosine seemed effective.

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