Development and In Vitro Evaluation of Self-Emulsifying Drug Delivery Systems Liquisolid Lozenges of Ibuprofen via Design of Experiments for Solubility Enhancement and Oral Epithelial Cell Permeation

No abstract is available for this paper.

• Publication year

  2026

• Venue

  OpenNano

• Publication date

  2026-01-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1016/j.onano.2026.100281
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• In vitro and ex vivo models of the oral mucosa as platforms for the validation of novel drug delivery systems

  2025cited by this paper
• Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells

  2025cited by this paper
• Utility of Piperine and Liquisolid Tablets to Enhance the Pharmacological Profile of Tacrolimus

  2025cited by this paper
• Sweeteners Show a Plasticizing Effect on PVP K30—A Solution for the Hot-Melt Extrusion of Fixed-Dose Amorphous Curcumin-Hesperetin Solid Dispersions

  2024cited by this paper
• Self-emulsifying drug delivery systems containing sulfate-based surfactants: Are they responsive to alkaline phosphatase?

  2024cited by this paper
• Treatment of Acute Sore Throat in Malaysia: A Consensus of Multidisciplinary Recommendations Using Modified Delphi Methodology

  2024cited by this paper
• Solubilization techniques used for poorly water-soluble drugs

  2024cited by this paper
• Nonporous amorphous superadsorbents for highly effective and selective adsorption of iodine in water

  2023cited by this paper
• CHARACTERISTICS AND STABILITY OF IBUPROFEN MICROEMULSION PER INJECTION USING A COMBINATION OF MEDIUM-CHAIN TRIGLYCERIDE OIL, EXTRA VIRGIN OLIVE OIL, AND VIRGIN COCONUT OIL AS THE OIL PHASE

  2022cited by this paper
• Influence of Process Parameters and Particle Size Distribution on Mechanical Properties of Tablets

  2022cited by this paper
• High-Shear Wet Granulation of SMEDDS Based on Mesoporous Carriers for Improved Carvedilol Solubility

  2022cited by this paper
• EFFECT OF THE TYPE AND CONCENTRATION OF MIXTURE SURFACTANT AND PROTEIN ON THE STABILITY OF NUTMEG OIL NANOEMULSION

  2022cited by this paper
• Home as the new frontier for the treatment of COVID-19: the case for anti-inflammatory agents

  2022cited by this paper
• A Critical Review on Engineering of d-Mannitol Crystals: Properties, Applications, and Polymorphic Control

  2022cited by this paper
• Self-emulsifying drug delivery systems: a novel approach to deliver drugs

  2022cited by this paper
• Mucoadhesive Nanocarriers as a Promising Strategy to Enhance Intracellular Delivery against Oral Cavity Carcinoma

  2022cited by this paper
• Mannitol Polymorphs as Carrier in DPIs Formulations: Isolation Characterization and Performance

  2021cited by this paper
• Development and optimisation of simulated salivary fluid for biorelevant oral cavity dissolution.

  2021cited by this paper
• Development and characterisation of ibuprofen-loaded nanoemulsion with enhanced oral bioavailability

  2020cited by this paper
• Mechanistic aspects of drug loading in liquisolid systems with hydrophilic lipid-based mixtures.

  2020cited by this paper
• Recovery of Active Pharmaceutical Ingredients from Unused Solid Dosage-Form Drugs

  2020cited by this paper
• Evaluation of Formulation Parameters on Permeation of Ibuprofen from Topical Formulations Using Strat-M® Membrane

  2020cited by this paper
• Solubility of Pharmaceutical Ingredients in Triglycerides.

  2019cited by this paper
• Engineering and monitoring cellular barrier models

  2018cited by this paper
• Self‐microemulsifying tablets prepared by direct compression for improved resveratrol delivery

  2018cited by this paper
• Impact of Porous Excipients on the Manufacturability and Product Performance of Solid Self-Emulsifying Drug Delivery Systems

  2018cited by this paper
• Understanding tablet defects in commercial manufacture and transfer

  2018cited by this paper
• Effect of Self-Microemulsifying Lipid Formulations on the Dissolution and Compaction Profiles of Tablets Containing Theophylline; a BCS Class I Compound -

  2018cited by this paper
• Drug-transporter mediated interactions between anthelminthic and antiretroviral drugs across the Caco-2 cell monolayers

  2017cited by this paper
• Pharmacokinetic and pharmacodynamic evaluation according to absorption differences in three formulations of ibuprofen

  2017cited by this paper
• Pain relief of sore throat with a new anti‐inflammatory throat lozenge, ibuprofen 25 mg: A randomised, double‐blind, placebo‐controlled, international phase III study

  2017cited by this paper
• Evaporation Behavior and Characterization of Eutectic Solvent and Ibuprofen Eutectic Solution

  2016cited by this paper
• Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity

  2016cited by this paper
• Thermal and X-ray diffraction analysis of lactose polymorph

  2015cited by this paper
• Low-energy formation of edible nanoemulsions by spontaneous emulsification: Factors influencing particle size

  2015cited by this paper
• Polymer co-processing of ibuprofen through compaction for improved oral absorption

  2015cited by this paper
• Integration of active pharmaceutical ingredient solid form selection and particle engineering into drug product design

  2015cited by this paper
• Self-Nanoemulsifying Drug Delivery System of Nifedipine: Impact of Hydrophilic–Lipophilic Balance and Molecular Structure of Mixed Surfactants

  2014cited by this paper
• Optimizing surfactant content to improve oral bioavailability of ibuprofen in microemulsions: just enough or more than enough?

  2014cited by this paper
• Development of self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system of telmisartan

  2014cited by this paper
• Co-proccessed excipients with enhanced direct compression functionality for improved tableting performance

  2012cited by this paper
• Online monitoring of transepithelial electrical resistance (TEER) in an apparatus for combined dissolution and permeation testing.

  2010cited by this paper
• DDSolver: An Add-In Program for Modeling and Comparison of Drug Dissolution Profiles

  2010cited by this paper
• Analgesic Effect from Ibuprofen Nanoparticles Inhaled by Male Mice

  2009cited by this paper
• Enhanced oral bioavailability of dexibuprofen by a novel solid self-emulsifying drug delivery system (SEDDS).

  2009cited by this paper
• Characterization and Physical Stability of Tolfenamic Acid-PVP K30 Solid Dispersions

  2007cited by this paper
• DSC study of sucrose melting.

  2006cited by this paper
• Micellar solubilization of ibuprofen: influence of surfactant head groups on the extent of solubilization

  2005cited by this paper
• Quantification of Crystallinity in Substantially Amorphous Materials by Synchrotron X-ray Powder Diffractometry

  2005cited by this paper
• The powder flow and compact mechanical properties of sucrose and three high-intensity sweeteners used in chewable tablets.

  2003cited by this paper
• Enhancing effect of polyoxyethylene alkyl ethers on the skin permeation of ibuprofen.

  2000cited by this paper
• Enhanced dissolution of furosemide by coprecipitating or cogrinding with crospovidone

  1998cited by this paper

• No citing papers are available for this paper.