First detection of one of the tick-borne lymphadenopathy (TIBOLA) etiological agent in ticks from a highly frequented sub-urban forest near Paris, France

In the context of global changes including climate, environmental and socio-economic modifications, the surveillance of tick populations in term of species distribution and harboured pathogens is an absolute necessity. With this aim in view, ticks were collected in May 2022 in an highly frequented suburban forest located near Paris, France. The objective was to identify tick species and tick-borne pathogens that may warrant long-term monitoring, as well as to assess added value of metatranscriptomic Next Generation Sequencing (mNGS) for the detection of known and possibly new pathogens in ticks. Both Dermacentor reticulatus and Ixodes ricinus were collected. In addition to expected pathogens detected in I. ricinus (i.e., Anaplasma, Babesia, and Borrelia species), we report the detection of Rickettsia conorii subsp. raoultii, a zoonotic bacterium never identified in the region before and transmitted by a tick species on the rise: D. reticulatus.

• Publication year

  2026

• Venue

  PLOS Global Public Health

• Publication date

  2026-01-12

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1371/journal.pgph.0005705PMID 41525246PMCID 12795371
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2017influential reference
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• The Tick Microbiome: Why Non-pathogenic Microorganisms Matter in Tick Biology and Pathogen Transmission

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• Environmental factors influencing tick densities over seven years in a French suburban forest

  2016influential reference
• Geographical distribution of Dermacentor marginatus and Dermacentor reticulatus in Europe.

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• Tick species, tick-borne pathogens and symbionts in an insular environment off the coast of Western France.

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• Changing distributions of ticks: causes and consequences

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• Human granulocytic anaplasmosis in eastern France: clinical presentation and laboratory diagnosis.

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