Islet Microencapsulation: Strategies and Clinical Status in Diabetes

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Current Diabetes Reports

• Publication date

  2017-05-18

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s11892-017-0877-0PMID 28523592
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

  2016cited by this paper
• Clinical Benefit of Islet Xenotransplantation for the Treatment of Type 1 Diabetes

  2016cited by this paper
• Homogeneous Canine Chest Phantom Construction: A Tool for Image Quality Optimization

  2016cited by this paper
• The Health Economic Value of Changes in Glycaemic Control, Weight and Rates of Hypoglycaemia in Type 1 Diabetes Mellitus

  2016cited by this paper
• Biocompatible Hydrogels for Microarray Cell Printing and Encapsulation

  2015cited by this paper
• Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

  2015cited by this paper
• Cardiac autonomic neuropathy in patients with diabetes mellitus.

  2014cited by this paper
• Device design and materials optimization of conformal coating for islets of Langerhans

  2014cited by this paper
• Membranes to achieve immunoprotection of transplanted islets.

  2014cited by this paper
• Islet and stem cell encapsulation for clinical transplantation.

  2014cited by this paper
• Sustained function of alginate-encapsulated human islet cell implants in the peritoneal cavity of mice leading to a pilot study in a type 1 diabetic patient

  2013cited by this paper
• Microbial Contamination of Clinical Islet Transplant Preparations Is Associated with Very Low Risk of Infection

  2013cited by this paper
• Alginate Microencapsulation of Human Islets Does Not Increase Susceptibility to Acute Hypoxia

  2013cited by this paper
• Reduction in Carotid Intima-Media Thickness After Pancreatic Islet Transplantation in Patients With Type 1 Diabetes

  2013cited by this paper
• Insulin therapy and hypoglycemia.

  2012cited by this paper
• Encapsulation of protein microfiber networks supporting pancreatic islets.

  2012cited by this paper
• Comparative Effectiveness and Safety of Methods of Insulin Delivery and Glucose Monitoring for Diabetes Mellitus

  2012cited by this paper
• Update on islet transplantation.

  2012cited by this paper
• Pig islet for xenotransplantation in human: structural and physiological compatibility for human clinical application.

  2012cited by this paper
• Improvement in Outcomes of Clinical Islet Transplantation: 1999–2010

  2012cited by this paper
• The prospect of induced pluripotent stem cells for diabetes mellitus treatment

  2011cited by this paper
• Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts

  2011cited by this paper
• State of the Art of Clinical Islet Transplantation and Novel Protocols of Immunosuppression

  2011cited by this paper
• Pig-to-Nonhuman Primates Pancreatic Islet Xenotransplantation: An Overview

  2011cited by this paper
• Company profile: Tissue regeneration for diabetes and neurological diseases at Living Cell Technologies.

  2010cited by this paper
• Clinical review: Realistic expectations and practical use of continuous glucose monitoring for the endocrinologist.

  2009cited by this paper
• Pig islets for clinical islet xenotransplantation

  2009cited by this paper
• Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

  2009cited by this paper
• Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

  2008cited by this paper
• Beta cell mass in diabetes: a realistic therapeutic target?

  2008cited by this paper
• Islet cell transplantation today

  2007cited by this paper
• Live encapsulated porcine islets from a type 1 diabetic patient 9.5 yr after xenotransplantation

  2007cited by this paper
• Improvement of Pancreatic Islet Cell Isolation for Transplantation

  2007cited by this paper
• International trial of the Edmonton protocol for islet transplantation.

  2006cited by this paper
• Microencapsulated pancreatic islet allografts into nonimmunosuppressed patients with type 1 diabetes: first two cases.

  2006cited by this paper
• Parameters favouring successful adult pig islet isolations for xenotransplantation in pig‐to‐primate models

  2006cited by this paper
• Type 1 diabetes: pathogenesis and prevention

  2006cited by this paper
• Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.

  2006cited by this paper
• The Bioartificial Pancreas: Progress and Challenges

  2005cited by this paper
• Towards a medically approved technology for alginate-based microcapsules allowing long-term immunoisolated transplantation

  2005cited by this paper
• Biological properties of photocrosslinked alginate microcapsules.

  2005cited by this paper
• Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

  2005cited by this paper
• Central Necrosis in Isolated Hypoxic Human Pancreatic Islets: Evidence for Postisolation Ischemia

  2005cited by this paper
• Transplantation for Type I Diabetes: Comparison of Vascularized Whole-Organ Pancreas With Isolated Pancreatic Islets

  2004cited by this paper
• The cost of diabetes in Latin America and the Caribbean.

  2003cited by this paper
• Mortality from heart disease in a cohort of 23,000 patients with insulin-treated diabetes

  2003cited by this paper
• Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome

  2002cited by this paper
• Interfacial photopolymerization of beta-cell clusters: approaches to reduce coating thickness using ionic and lipophilic dyes.

  2001cited by this paper
• Insulin production by human embryonic stem cells.

  2001cited by this paper
• Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.

  2000cited by this paper
• Alginate hydrogel microspheres and microcapsules prepared by spinning disk atomization.

  2000cited by this paper
• Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice.

  2000cited by this paper
• Engineering and material considerations in islet cell transplantation.

  1999cited by this paper
• Selected Aspects of the Microencapsulation of Mammalian Cells in HEMA‐MMA a

  1997cited by this paper
• Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression.

  1996cited by this paper
• Studies on Small (<300 μm) Microcapsules: II — Parameters Governing the Production of Alginate Beads by High Voltage Electrostatic Pulses

  1994cited by this paper
• Insulin independence in a type 1 diabetic patient after encapsulated islet transplantation.

  1994cited by this paper
• Alginate as immobilization matrix for cells.

  1990cited by this paper
• Microencapsulation of CHO cells in a hydroxyethyl methacrylate-methyl methacrylate copolymer.

  1987cited by this paper

• Progress in Hyaluronan-Based Nanoencapsulation Systems for Smart Drug Release and Medical Applications

  2025cites this paper
• An injectable and retrievable bioartificial pancreas fabricated by time-sequentially assembling islets-laden microgels for minimally invasive treatment of type 1 diabetes

  2024cites this paper
• Global scientific trends on the islet transplantation in the 21st century: A bibliometric and visualized analysis

  2024cites this paper
• pO2 reporter composite hydrogel macroencapsulation devices for magnetic resonance imaging oxygen quantification.

  2024cites this paper
• Status of islet transplantation and innovations to sustainable outcomes: novel sites, cell sources, and drug delivery strategies

  2024cites this paper
• Recent advances in immune checkpoint inhibitor-induced type 1 diabetes mellitus.

  2023cites this paper
• A novel bioartificial pancreas fabricated via islets microencapsulation in anti-adhesive core-shell microgels and macroencapsulation in a hydrogel scaffold prevascularized in vivo

  2023cites this paper
• Three-dimensional bioprinting of functional β-islet-like constructs

  2023cites this paper
• Engineered Fibrous NiTi Scaffolds with Cultured Hepatocytes for Liver Regeneration in Rats.

  2023cites this paper
• Narrative review of the role of technology in pediatric diabetes: from testing blood glucose to subcutaneous automated therapy and hope for cure

  2023cites this paper
• ECM-based bioactive microencapsulation significantly improves islet function and graft performance.

  2023cites this paper
• Emerging Strategies to Bypass Transplant Rejection via Biomaterial-Assisted Immunoengineering: Insights from Islets and Beyond.

  2023cites this paper
• Emerging Strategies to Bypass Transplant Rejection via Biomaterial-Assisted Immunoengineering

  2023cites this paper
• Tissue engineering approaches and generation of insulin-producing cells to treat type 1 diabetes

  2022cites this paper
• Parallel Evaluation of Polyethylene Glycol Conformal Coating and Alginate Microencapsulation as Immunoisolation Strategies for Pancreatic Islet Transplantation

  2022cites this paper
• Augmenting engraftment of beta cell replacement therapies for T1DM

  2021cites this paper
• Heterogeneous toroidal spiral particles for islet encapsulation.

  2021cites this paper
• Engineering microcapsules to construct vascularized human brain organoids

  2021cites this paper
• Development of a Platform for the Biofabrication of Endocrine Pancreatic Tissue Constructs through Co-Axial Micro-Extrusion

  2021cites this paper
• An Overview of Engineered Hydrogel-Based Biomaterials for Improved β-Cell Survival and Insulin Secretion

  2021cites this paper
• Application and Progress of Stem Cells in the Treatment of Diabetes

  2021cites this paper
• Towards effective beta-cell replacement through understanding and targeting of the autoreactive immune response during onset of type 1 diabetes

  2021cites this paper
• Noninvasive Fluorine-19 Magnetic Resonance Relaxometry Measurement of the Partial Pressure of Oxygen in Acellular Perfluorochemical-loaded Alginate Microcapsules Implanted in the Peritoneal Cavity of Nonhuman Primates

  2020cites this paper
• Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual‐Function MRI Visible and Retrievable Microcapsules

  2020cites this paper
• Conformal coating

  2020cites this paper
• INFLUENCE OF THE STERILIZATION METHOD ON THE PROLIFERATION AND VIABILITY OF MOLT-4 CELLS ENCAPSULATED IN ALGINATE GEL

  2020cites this paper
• Hydrogels in Emerging Technologies for Type 1 Diabetes.

  2020cites this paper
• A Low-Cost Open Source Device for Cell Microencapsulation

  2020cites this paper
• Editorial: Enabling Biomaterials for New Biomedical Technologies and Clinical Therapies

  2020cites this paper
• An Efficient and Footprint-Free Protocol for the Transdifferentiation of Hepatocytes Into Insulin-Producing Cells With IVT mRNAs

  2020cites this paper
• Oxidative stress in pancreatic alpha and beta cells as a selection criterion for biocompatible biomaterials.

  2020cites this paper
• Interconnected Toroidal Hydrogels for Islet Encapsulation

  2019cites this paper
• Nanotechnology in cell replacement therapies for type 1 diabetes.

  2019cites this paper
• Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus

  2019cites this paper
• Bioengineering a pre-vascularized pouch for subsequent islet transplantation using VEGF-loaded polylactide capsules.

  2019cites this paper
• Oxidative stress in alpha and beta cells as a selection criterion for biocompatible biomaterials

  2019cites this paper
• Polymeric Approaches to Reduce Tissue Responses Against Devices Applied for Islet-Cell Encapsulation

  2019cites this paper
• Liraglutide Immobilized on Poly(lactic-co-glycolic acid) Polymer Films Induced the Differentiation of Islet β-Like Cells from Bone Marrow Mesenchymal Stem Cells

  2019cites this paper
• Physical Protection of Pancreatic Islets for Transplantation Physical Protection of Pancreatic Islets for Transplantation

  2018cites this paper
• Conformal coating by multilayer nano-encapsulation for the protection of human pancreatic islets: In-vitro and in-vivo studies.

  2018cites this paper
• Islet encapsulation.

  2018cites this paper
• Physical Protection of Pancreatic Islets for Transplantation

  2017cites this paper
• Satisfacción con el tratamiento y calidad de vida en pacientes con diabetes mellitus tipo 1 e hipoglucemias tratados con insulina Degludec

  2017cites this paper
• Mikroenkapsüle edilen paratiroid hücrelerinin in-vitro optimizasyonu

  2017influential citation