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Analysis of the Application Value of Various Prediction Models for Adnexal Mass During Pregnancy: A Single-Center Retrospective Study.

Yaning Niu,Jie Shen,Jiayi Ding,H. Zhong,Huafeng Wang,Hui Chen

Published 2026 in Journal of ultrasound in medicine

ABSTRACT

OBJECTIVES Adnexal masses during pregnancy are rare. This study aimed to evaluate the clinical application value of 3 prediction models: Assessment of Different NEoplasias in the adneXa (ADNEX), Simple Rules (SR), and Ovarian-Adnexal Reporting and Data System (O-RADS) in pregnant patients with adnexal masses and summarizes the clinical and ultrasonographic characteristics of adnexal masses during pregnancy. METHODS A total of 65 patients confirmed by surgery and pathology were included in this retrospective single-center study. Three predictive models were applied to assess adnexal masses prior to surgery. The area under the ROC curve (AUC), accuracy, sensitivity, and specificity were calculated to evaluate the diagnostic efficiency of different models. RESULTS Of these cases, 62 (95.4%) were benign and 3 (4.6%) were malignant. The median diameter of benign masses was 46.0 mm, while the median maximum diameter of malignant masses was 103.0 mm. The difference in maximum diameters between the 2 groups was statistically significant (p < .05). The performance of the predictive models varied: the area under the ROC curve (AUC) was 0.64, 0.91, and 0.94 for ADNEX, SR, and O-RADS. The differences in AUCs among these models were not statistically significant. CONCLUSIONS The incidence of malignant adnexal masses during pregnancy is low. Malignant masses, in contrast to benign masses, typically exhibit larger maximum diameters. SR and O-RADS showed good diagnostic efficacy and had certain clinical value in evaluating the benign and malignant of adnexal masses during pregnancy.

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