The Abelson interactor (Abi) has a conserved role in Arp2/3-dependent actin polymerization, regulating WASP and WAVE. In this study, the function of Abi was analyzed in the context of the developing fly visual system, and the steps in the molecular regulation of WAVE activity by its regulatory complex in vivo were identified.
Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila
Raiko Stephan,Christina Gohl,Astrid Fleige,C. Klämbt,S. Bogdan
Published 2011 in Molecular Biology of the Cell
ABSTRACT
PUBLICATION RECORD
- Publication year
2011
- Venue
Molecular Biology of the Cell
- Publication date
2011-11-01
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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