The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Neuron

• Publication date

  2018-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.neuron.2018.06.031PMID 30001508
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis.

  2018cited by this paper
• Beyond proneural: emerging functions and regulations of proneural proteins.

  2017cited by this paper
• Epigenetic Mistakes in Neurodevelopmental Disorders

  2017cited by this paper
• Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex

  2017influential reference
• Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells

  2017cited by this paper
• PRDM16 Suppresses MLL1r Leukemia via Intrinsic Histone Methyltransferase Activity.

  2016cited by this paper
• Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity.

  2016cited by this paper
• Mutations in Human Accelerated Regions Disrupt Cognition and Social Behavior.

  2016cited by this paper
• The Multifaceted Roles of PRDM16: Adipose Biology and Beyond.

  2016cited by this paper
• deepTools2: a next generation web server for deep-sequencing data analysis

  2016cited by this paper
• Evolutionary changes in promoter and enhancer activity during human corticogenesis

  2015cited by this paper
• Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

  2015cited by this paper
• Reprogramming of cell fate: epigenetic memory and the erasure of memories past

  2015cited by this paper
• PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program

  2015cited by this paper
• The ubiquitin ligase PDZRN3 is required for vascular morphogenesis through Wnt/planar cell polarity signalling

  2014cited by this paper
• Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.

  2014cited by this paper
• Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

  2014influential reference
• Radial glia require PDGFD/PDGFRß signaling in human but not mouse neocortex

  2014cited by this paper
• MARIS: Method for Analyzing RNA following Intracellular Sorting

  2014influential reference
• Target analysis by integration of transcriptome and ChIP-seq data with BETA

  2013influential reference
• STAR: ultrafast universal RNA-seq aligner

  2013influential reference
• A high-resolution enhancer atlas of the developing telencephalon.

  2013cited by this paper
• Genome-wide chromatin state transitions associated with developmental and environmental cues.

  2013cited by this paper
• Chromatin regulation by BAF170 controls cerebral cortical size and thickness.

  2013cited by this paper
• featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

  2013influential reference
• Transcriptional co-regulation of neuronal migration and laminar identity in the neocortex

  2012cited by this paper
• The Prdm family: expanding roles in stem cells and development

  2012cited by this paper
• Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.

  2012cited by this paper
• An encyclopedia of mouse DNA elements (Mouse ENCODE)

  2012cited by this paper
• Neural stem and progenitor cells shorten S-phase on commitment to neuron production

  2011cited by this paper
• Measuring reproducibility of high-throughput experiments

  2011influential reference
• Cutadapt removes adapter sequences from high-throughput sequencing reads

  2011influential reference
• Development and evolution of the human neocortex.

  2011cited by this paper
• A unique chromatin signature uncovers early developmental enhancers in humans

  2011cited by this paper
• REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

  2011influential reference
• Histone H3K27ac separates active from poised enhancers and predicts developmental state

  2010cited by this paper
• A Transient Transgenic RNAi Strategy for Rapid Characterization of Gene Function during Embryonic Development

  2010influential reference
• PDZRN3 Negatively Regulates BMP-2–induced Osteoblast Differentiation through Inhibition of Wnt Signaling

  2010influential reference
• Epigenetic control of neural precursor cell fate during development

  2010cited by this paper
• Prdm16 is required for normal palatogenesis in mice.

  2010influential reference
• Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress

  2010influential reference
• Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

  2010influential reference
• Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

  2009influential reference
• Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.

  2009cited by this paper
• Use of the viral 2A peptide for bicistronic expression in transgenic mice

  2008cited by this paper
• The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone.

  2008cited by this paper
• Model-based Analysis of ChIP-Seq (MACS)

  2008influential reference
• Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex.

  2008cited by this paper
• Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex.

  2008influential reference
• Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

  2008cited by this paper
• Neuronal subtype specification in the cerebral cortex

  2007cited by this paper
• g:Profiler—a web-based toolset for functional profiling of gene lists from large-scale experiments

  2007influential reference
• Transcriptional control of brown fat determination by PRDM16.

  2007cited by this paper
• Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

  2007cited by this paper
• Differential Notch signalling distinguishes neural stem cells from intermediate progenitors.

  2007cited by this paper
• Genetic targeting of principal neurons in neocortex and hippocampus of NEX‐Cre mice

  2006cited by this paper
• The multipolar stage and disruptions in neuronal migration.

  2006cited by this paper
• GABA-A receptors regulate neocortical neuronal migration in vitro and in vivo.

  2006influential reference
• Distinct Morphological Stages of Dentate Granule Neuron Maturation in the Adult Mouse Hippocampus

  2006cited by this paper
• Pax6, Tbr2, and Tbr1 Are Expressed Sequentially by Radial Glia, Intermediate Progenitor Cells, and Postmitotic Neurons in Developing Neocortex

  2005influential reference
• Cortical neurons arise in symmetric and asymmetric division zones and migrate through specific phases

  2004cited by this paper
• Lentivirus-delivered stable gene silencing by RNAi in primary cells.

  2003cited by this paper
• Electroporation and RNA interference in the rodent retina in vivo and in vitro

  2003cited by this paper
• Cortical Excitatory Neurons and Glia, But Not GABAergic Neurons, Are Produced in the Emx1-Expressing Lineage

  2002cited by this paper
• Neurons derived from radial glial cells establish radial units in neocortex

  2001cited by this paper
• Fibroblast Growth Factor-2 Activates a Latent Neurogenic Program in Neural Stem Cells from Diverse Regions of the Adult CNS

  1999cited by this paper
• Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split.

  1998cited by this paper
• Essential role of alpha 6 integrins in cortical and retinal lamination.

  1998cited by this paper

• Prdm16 Amplifies Notch Signaling and Suppresses Venous Lineage Specification to Prevent Arteriovenous Malformations During Vascular Development.

  2026cites this paper
• New insights into neurodevelopmental disorders by whole genome sequencing of 100 families from Italy

  2026cites this paper
• PRDM paralogs are required for Meckel’s cartilage formation during mandibular bone development

  2025cites this paper
• PRDM paralogs are required for Meckel's cartilage formation during mandibular bone development.

  2025cites this paper
• PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function

  2024cites this paper
• PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function

  2023cites this paper
• PRDM paralogs antagonistically balance Wnt/β-catenin activity during craniofacial chondrocyte differentiation.

  2022cites this paper
• Microglia homeostasis mediated by epigenetic ARID1A regulates neural progenitor cells response and leads to autism-like behaviors

  2022cites this paper
• PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle

  2021cites this paper
• The duality of PRDM proteins: epigenetic and structural perspectives

  2021cites this paper
• YAP/TAZ Maintain the Proliferative Capacity and Structural Organization of Radial Glial Cells During Brain Development

  2021cites this paper
• Proteomic analysis identifies the E3 ubiquitin ligase Pdzrn3 as a regulatory target of Wnt5a-Ror signaling

  2021cites this paper
• Enhancer RNAs predict enhancer–gene regulatory links and are critical for enhancer function in neuronal systems

  2020cites this paper
• A Topological Cluster of Differentially Regulated Genes in Mice Lacking PER3

  2020cites this paper
• PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain

  2020cites this paper
• PRDM16 establishes lineage-specific transcriptional program to promote temporal progression of neural progenitors in the mouse neocortex

  2019cites this paper
• The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development

  2019cites this paper
• Genomic Enhancers in Brain Health and Disease

  2019cites this paper
• PRDM16 Represses the Pig White Lipogenesis through Promoting Lipolysis Activity

  2019cites this paper
• Epigenetic cues modulating the generation of cell‐type diversity in the cerebral cortex

  2018cites this paper