Evidence that β7 Integrin Regulates Hematopoietic Stem Cell Homing and Engraftment Through Interaction with MAdCAM-1

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Stem Cells and Development

• Publication date

  2016-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/scd.2014.0551PMID 26422691PMCID PMC4692116
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CXC chemokine ligand 12 (CXCL12) and its receptor CXCR4

  2014influential reference
• Hypoxia Promotes Migration and Induces CXCR4 Expression via HIF-1α Activation in Human Osteosarcoma

  2014cited by this paper
• Stage‐Specific Roles for Cxcr4 Signaling in Murine Hematopoietic Stem/Progenitor Cells in the Process of Bone Marrow Repopulation

  2014cited by this paper
• The influence of hypoxia on CML trafficking through modulation of CXCR4 and E-cadherin expression

  2013cited by this paper
• Differential representation of B cell subsets in mixed bone marrow chimera mice due to expression of allelic variants of CD45 (CD45.1/CD45.2).

  2013cited by this paper
• Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib

  2012cited by this paper
• Hypoxia induces CXCR4 expression and biological activity in gastric cancer cells through activation of hypoxia-inducible factor-1α.

  2012cited by this paper
• Stem cell heterogeneity: implications for aging and regenerative medicine.

  2012cited by this paper
• A novel perspective on stem cell homing and mobilization: review on bioactive lipids as potent chemoattractants and cationic peptides as underappreciated modulators of responsiveness to SDF-1 gradients

  2012cited by this paper
• Robo4 cooperates with CXCR4 to specify hematopoietic stem cell localization to bone marrow niches.

  2011cited by this paper
• Involvement of oxidative stress and mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in inflammatory bowel disease

  2011cited by this paper
• Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression.

  2011cited by this paper
• Stromal-Derived Factor-1/CXCR4 Signaling: Indispensable Role in Homing and Engraftment of Hematopoietic Stem Cells in Bone Marrow

  2011influential reference
• Distinguishing mast cell and granulocyte differentiation at the single-cell level.

  2010cited by this paper
• Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1.

  2010cited by this paper
• TNF-α Regulates the Effects of Irradiation in the Mouse Bone Marrow Microenvironment

  2010cited by this paper
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  2010cited by this paper
• Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4

  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010influential reference
• Increased expression of CXCR4 and integrin αM in hypoxia‐preconditioned cells contributes to improved cell retention and angiogenic potency

  2009cited by this paper
• Role of beta7 integrins in intestinal lymphocyte homing and retention.

  2009cited by this paper
• Bone marrow CXCR4 induction by cultivation enhances therapeutic angiogenesis.

  2009cited by this paper
• Stem cell trafficking in tissue development, growth, and disease.

  2008cited by this paper
• Role of MAdCAM-1 and its ligand on the homing of transplanted hematopoietic cells in irradiated mice.

  2008influential reference
• Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells.

  2007cited by this paper
• Regulation of CXCR4 signaling.

  2007cited by this paper
• Reduced retention of radioprotective hematopoietic cells within the bone marrow microenvironment in CXCR4-/- chimeric mice.

  2006cited by this paper
• Molecular mechanisms of cell recruitment to inflammatory sites: general and tissue-specific pathways.

  2006cited by this paper
• Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells.

  2005cited by this paper
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  2005cited by this paper
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  2004influential reference
• Deletion of α4 Integrins from Adult Hematopoietic Cells Reveals Roles in Homeostasis, Regeneration, and Homing

  2003cited by this paper
• Regulation of the Chemokine Receptor CXCR4 by Hypoxia

  2003cited by this paper
• The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2mnull mice

  2002cited by this paper
• Treatment of circulating CD34(+) cells with SDF-1alpha or anti-CXCR4 antibody enhances migration and NOD/SCID repopulating potential.

  2002cited by this paper
• Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting*

  2001cited by this paper
• The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice.

  2000cited by this paper
• Trafficking of the HIV Coreceptor CXCR4

  1999cited by this paper
• Expression of mucosal addressin cell adhesion molecule‐1 (MAdCAM‐1) in acute and chronic inflammation

  1999cited by this paper
• Endothelial selectins and vascular cell adhesion molecule-1 promote hematopoietic progenitor homing to bone marrow.

  1998cited by this paper
• Expression mapping of adhesion receptor genes during differentiation of individual hematopoietic precursors.

  1997cited by this paper
• Regulation of Human Chemokine Receptors CXCR4

  1997cited by this paper
• Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

  1997cited by this paper
• Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins

  1996cited by this paper
• The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen.

  1995cited by this paper
• Induction of the gene encoding mucosal vascular addressin cell adhesion molecule 1 by tumor necrosis factor alpha is mediated by NF-kappa B proteins.

  1995cited by this paper
• Fibronectin and VLA-4 in haematopoietic stem cell–microenvironment interactions

  1991cited by this paper

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  2025cites this paper
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  2023cites this paper
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  2023cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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