Clinical variable-based decision-support model for rapid differentiation of hemorrhagic and ischemic stroke at emergency department presentation in South Korea

Jae-Woo Kim,Jin-Heon Jeong,Moon-Ku Han,Sang-Hoon Han,Kara Kim,Seung Park,Dong-Ick Shin,Kyuhee Yum

Published 2026 in Acute and Critical Care

ABSTRACT

the model output toward HS, whereas atrial fibrillation shifted predictions toward IS. Conclusions: A clinical variable-only model can support early HS vs. IS subtype suspicion at ED presentation among patients managed in an acute-stroke pathway without requiring laboratory tests. Performance decreased on independent external validation, suggesting potential site-related differences and the need for prospective evaluation and calibration. Stroke mimics were not included and should be addressed in future studies.

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