Small-GTPase-Associated Signaling by the Guanine Nucleotide Exchange Factors CpDock180 and CpCdc24, the GTPase Effector CpSte20, and the Scaffold Protein CpBem1 in Claviceps purpurea

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Eukaryotic Cell

• Publication date

  2014-01-31

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1128/EC.00332-13PMID 24489041PMCID PMC4000099
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2013cited by this paper
• Regulation of small GTPases by GEFs, GAPs, and GDIs.

  2013cited by this paper
• Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7.

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  2013cited by this paper
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  2013cited by this paper
• Tools for Botrytis cinerea: New expression vectors make the gray mold fungus more accessible to cell biology approaches.

  2012cited by this paper
• Cla4 kinase triggers destruction of the Rac1-GEF Cdc24 during polarized growth in Ustilago maydis

  2011cited by this paper
• Polarity proteins Bem1 and Cdc24 are components of the filamentous fungal NADPH oxidase complex

  2011influential reference
• Functional Characterization and Cellular Dynamics of the CDC-42 – RAC – CDC-24 Module in Neurospora crassa

  2011cited by this paper
• The small GTPase BcCdc42 affects nuclear division, germination and virulence of the gray mold fungus Botrytis cinerea.

  2011cited by this paper
• The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth

  2010cited by this paper
• Transcriptional profiling for Aspergillusnidulans HogA MAPK signaling pathway in response to fludioxonil and osmotic stress.

  2009cited by this paper
• Characterisation of Aspergillus nidulans polarisome component BemA.

  2008cited by this paper
• The NADPH oxidase Cpnox1 is required for full pathogenicity of the ergot fungus Claviceps purpurea.

  2008cited by this paper
• Activation of Rac1 by the guanine nucleotide exchange factor Dck1 is required for invasive filamentous growth in the pathogen Candida albicans.

  2008cited by this paper
• The small GTPase Rac and the p21‐activated kinase Cla4 in Claviceps purpurea: interaction and impact on polarity, development and pathogenicity

  2008cited by this paper
• NADPH oxidases are involved in differentiation and pathogenicity in Botrytis cinerea.

  2008cited by this paper
• Cdk5 kinase regulates the association between adaptor protein Bem1 and GEF Cdc24 in the fungus Ustilago maydis

  2008cited by this paper
• A Ras1‐Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformans

  2007cited by this paper
• Regulation of hyphal morphogenesis by cdc42 and rac1 homologues in Aspergillus nidulans

  2007cited by this paper
• Structure and Function of the PB1 Domain, a Protein Interaction Module Conserved in Animals, Fungi, Amoebas, and Plants

  2007cited by this paper
• GEFs and GAPs: critical elements in the control of small G proteins.

  2007cited by this paper
• A Novel Cdc42-interacting Domain of the Yeast Polarity Establishment Protein Bem1

  2007cited by this paper
• Unusual Interplay of Two Types of Ras Activators, RasGRP and SOS, Establishes Sensitive and Robust Ras Activation in Lymphocytes

  2007cited by this paper
• Rac1 and Cdc42 Have Different Roles in Candida albicans Development

  2006cited by this paper
• Rac1 and Cdc42 regulate hyphal growth and cytokinesis in the dimorphic fungus Ustilago maydis

  2006cited by this paper
• Association of CNK1 with Rho guanine nucleotide exchange factors controls signaling specificity downstream of Rho.

  2005cited by this paper
• Aspergillus nidulans HOG pathway is activated only by two‐component signalling pathway in response to osmotic stress

  2005cited by this paper
• A CDC42 Homologue in Claviceps purpurea Is Involved in Vegetative Differentiation and Is Essential for Pathogenicity

  2005cited by this paper
• GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

  2005cited by this paper
• A Rac Homolog Functions Downstream of Ras1 To Control Hyphal Differentiation and High-Temperature Growth in the Pathogenic Fungus Cryptococcus neoformans

  2005cited by this paper
• Two PAK kinase genes, CHM1 and MST20, have distinct functions in Magnaporthe grisea.

  2004cited by this paper
• An ste20 Homologue in Ustilago maydis Plays a Role in Mating and Pathogenicity

  2004cited by this paper
• Cdc24, the GDP-GTP Exchange Factor for Cdc42, Is Required for Invasive Hyphal Growth of Candida albicans

  2003cited by this paper
• The Cdc42 Binding and Scaffolding Activities of the Fission Yeast Adaptor Protein Scd2*

  2003cited by this paper
• Scaffold-mediated symmetry breaking by Cdc42p

  2003cited by this paper
• Control of morphogenesis and actin localization by the Penicillium marneffei RAC homolog

  2003cited by this paper
• Regulation of p70 S6 Kinase by Complex Formation between the Rac Guanine Nucleotide Exchange Factor (Rac-GEF) Tiam1 and the Scaffold Spinophilin*

  2003cited by this paper
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  2002cited by this paper
• Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

  2002cited by this paper
• Regulation of Kinase Activity and Signaling by the Yeast p 21-Activated Kinase Ste 20

  2002cited by this paper
• A positive feedback loop stabilizes the guanine‐nucleotide exchange factor Cdc24 at sites of polarization

  2002cited by this paper
• Unconventional Rac-GEF activity is mediated through the Dock180–ELMO complex

  2002cited by this paper
• Mating-Type-Specific and Nonspecific PAK Kinases Play Shared and Divergent Roles in Cryptococcus neoformans

  2002cited by this paper
• CPMK2, an SLT2‐homologous mitogen‐activated protein (MAP) kinase, is essential for pathogenesis of Claviceps purpurea on rye: evidence for a second conserved pathogenesis‐related MAP kinase cascade in phytopathogenic fungi

  2002cited by this paper
• CDC42 Is Required for Polarized Growth in Human Pathogen Candida albicans

  2002cited by this paper
• Generation of conditional lethal Candida albicans mutants by inducible deletion of essential genes

  2002cited by this paper
• Cdc42 Regulation of Kinase Activity and Signaling by the Yeast p21-Activated Kinase Ste20

  2002cited by this paper
• Cell polarity and hyphal morphogenesis are controlled by multiple rho-protein modules in the filamentous ascomycete Ashbya gossypii.

  2001cited by this paper
• Assembly of Scaffold-mediated Complexes Containing Cdc42p, the Exchange Factor Cdc24p, and the Effector Cla4p Required for Cell Cycle-regulated Phosphorylation of Cdc24p*

  2001influential reference
• High-efficiency transformation of plasmid DNA into yeast.

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• The CDC42 Homolog of the Dimorphic FungusPenicillium marneffei Is Required for Correct Cell Polarization during Growth but Not Development

  2001cited by this paper
• Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch.

  2000cited by this paper
• Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast.

  2000influential reference
• Vav2 Is an Activator of Cdc42, Rac1, and RhoA*

  2000cited by this paper
• Yeast Cdc42 GTPase and Ste20 PAK‐like kinase regulate Sho1‐dependent activation of the Hog1 MAPK pathway

  2000cited by this paper
• Genetic Evidence for Pak1 Autoinhibition and Its Release by Cdc42

  1999cited by this paper
• Rho guanine dissociation inhibitors: pivotal molecules in cellular signalling.

  1999cited by this paper
• Variation in Karyotype and Ploidy Level Among Field Isolates of Claviceps purpurea

  1999cited by this paper
• Cdc42: An Essential Rho-Type GTPase Controlling Eukaryotic Cell Polarity

  1999cited by this paper
• A Conserved Negative Regulatory Region in αPAK: Inhibition of PAK Kinases Reveals Their Morphological Roles Downstream of Cdc42 and Rac1

  1998cited by this paper
• Activation of Rac1 by a Crk SH3-binding protein, DOCK180.

  1998cited by this paper
• Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes.

  1998cited by this paper
• Cla4p, a Saccharomyces cerevisiae Cdc42p-activated kinase involved in cytokinesis, is activated at mitosis

  1997cited by this paper
• Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity.

  1997cited by this paper
• Virulence and hyphal formation of Candida albicans require the Ste20p-like protein kinase CaCla4p.

  1997cited by this paper
• Functional analysis of the interaction between the small GTP binding protein Cdc42 and the Ste20 protein kinase in yeast.

  1996cited by this paper
• Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast.

  1996cited by this paper
• Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.

  1996cited by this paper
• DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

  1996cited by this paper
• Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.

  1995cited by this paper
• Purification of recombinant Rho/Rac/G25K from Escherichia coli.

  1995cited by this paper
• Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe.

  1995cited by this paper
• Construction of a set of convenient saccharomyces cerevisiae strains that are isogenic to S288C

  1995cited by this paper
• Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3.

  1994cited by this paper
• Cooperative interaction of S. pombe proteins required for mating and morphogenesis.

  1994cited by this paper
• Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands.

  1994cited by this paper
• The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.

  1993cited by this paper
• An osmosensing signal transduction pathway in yeast.

  1993cited by this paper
• Rapid extraction of fungal DNA for PCR amplification.

  1992cited by this paper
• Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product

  1991cited by this paper
• CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae

  1990cited by this paper
• A novel genetic system to detect protein–protein interactions

  1989cited by this paper
• The predicted DBL oncogene product defines a distinct class of transforming proteins.

  1988cited by this paper
• Biology of industrial microorganisms

  1985cited by this paper
• Genetics of the ergot fungus Claviceps purpurea

  1982cited by this paper
• Host infection by Claviceps purpurea

  1980cited by this paper
• Genetics of the ergot fungus Claviceps purpurea

  1978cited by this paper
• Differentiation of Claviceps purpurea in axenic culture.

  1976cited by this paper
• The story of ergot.

  1970cited by this paper
• Studies on lysogenesis

  1956cited by this paper
• STUDIES ON LYSOGENESIS I

  1951cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

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  2021cites this paper
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  2018cites this paper
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  2018cites this paper
• Insights into the molecular interplay of virulence factors in Botrytis cinerea

  2017cites this paper
• The Colletotrichum gloeosporioides RhoB regulates cAMP and stress response pathways and is required for pathogenesis.

  2016cites this paper
• Phosphoproteome analysis of B. cinerea in response to different plant-based elicitors.

  2016cites this paper
• Polarity proteins Mrcdc24 and Mrbem1 required for hypha growth and microsclerotia formation in Metarhizium rileyi

  2016cites this paper
• Reactive Oxygen Species in the Botrytis – Host Interaction

  2016cites this paper
• BcIqg1, a fungal IQGAP homolog, interacts with NADPH oxidase, MAP kinase and calcium signaling proteins and regulates virulence and development in Botrytis cinerea

  2016cites this paper
• Regulation of hyphal morphogenesis by Ras and Rho small GTPases

  2015cites this paper
• BcNoxD, a putative ER protein, is a new component of the NADPH oxidase complex in Botrytis cinerea

  2015cites this paper
• Characterization of Rho GTPase GAP/GEF modules in the ascomycete Neurospora crassa

  2015cites this paper
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  2014cites this paper