Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Biochemical Journal

• Publication date

  2000-07-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1042/0264-6021:3490605PMID 10880360PMCID PMC1221184
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Novel B Lymphocyte–Associated Adaptor Protein, Bam32, Regulates Antigen Receptor Signaling Downstream of Phosphatidylinositol 3-Kinase

  2000cited by this paper
• A Novel Positive Feedback Loop Mediated by the Docking Protein Gab1 and Phosphatidylinositol 3-Kinase in Epidermal Growth Factor Receptor Signaling

  2000cited by this paper
• The PI3K-PDK1 connection: more than just a road to PKB.

  2000cited by this paper
• DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides.

  1999cited by this paper
• The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function*

  1999cited by this paper
• Structural basis for selective inhibition of Src family kinases by PP1.

  1999cited by this paper
• Expression Cloning of Protein Targets for 3-Phosphorylated Phosphoinositides*

  1999cited by this paper
• Intracellular signalling: PDK1--a kinase at the hub of things.

  1999cited by this paper
• Protein kinase B (c-Akt): a multifunctional mediator of phosphatidylinositol 3-kinase activation.

  1998cited by this paper
• Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav.

  1998cited by this paper
• Regulation of GRP1-catalyzed ADP Ribosylation Factor Guanine Nucleotide Exchange by Phosphatidylinositol 3,4,5-Trisphosphate*

  1998cited by this paper
• The role of PI 3-kinase in insulin action.

  1998cited by this paper
• The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2.

  1998cited by this paper
• Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B.

  1998cited by this paper
• Identification and analysis of PH domain‐containing targets of phosphatidylinositol 3‐kinase using a novel in vivo assay in yeast

  1998cited by this paper
• Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases.

  1997cited by this paper
• Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.

  1997cited by this paper
• 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

  1997cited by this paper
• Phosphoinositide 3-kinases: a conserved family of signal transducers.

  1997cited by this paper
• Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways.

  1996cited by this paper
• Mechanism of activation of protein kinase B by insulin and IGF‐1.

  1996cited by this paper
• Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

  1996cited by this paper
• Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf.

  1995cited by this paper
• Recognition and specificity in protein tyrosine kinase-mediated signalling.

  1995cited by this paper
• Myristylation and palmitylation of Src family members: The fats of the matter

  1994cited by this paper
• Myristylation and palmitylation of Src family members: the fats of the matter.

  1994cited by this paper
• A synthetic peptide derived from p34cdc2 is a specific and efficient substrate of src-family tyrosine kinases.

  1992cited by this paper
• The src family of tyrosine protein kinases in hemopoietic signal transduction

  1992cited by this paper
• The Src family of tyrosine protein kinases in hemopoietic signal transduction

  1992cited by this paper
• Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.

  1992cited by this paper

• In-depth PtdIns(3,4,5)P3 signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function.

  2017cites this paper
• Quantitative phosphoproteomics for studying B-cell receptor signaling in Burkitt's lymphoma.

  2017cites this paper
• Investigating the effects of inositol depletion using a simple eukaryotic organism, Dictyostelium discoideum

  2016cites this paper
• The Inositol-3-Phosphate Synthase Biosynthetic Enzyme Has Distinct Catalytic and Metabolic Roles

  2016cites this paper
• The inositol-3-phosphate synthase biosynthetic enzyme has distinct catalytic and 1 metabolic roles 2 3 4

  2016cites this paper
• Membrane and Protein Interactions of the Pleckstrin Homology Domain Superfamily

  2015cites this paper
• Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction

  2015cites this paper
• Signaling at the Golgi Apparatus During Cell Migration and Implication for Cancer Cell Metastasis

  2015cites this paper
• Regulation of inositol biosynthesis and cellular consequences of inositol depletion: Implications for the mechanism of action of valproate

  2014cites this paper
• Deciphering of ADP‐induced, phosphotyrosine‐dependent signaling networks in human platelets by Src‐homology 2 region (SH2)‐profiling

  2013cites this paper
• Bam32/DAPP1 Promotes B Cell Adhesion and Formation of Polarized Conjugates with T Cells

  2010influential citation
• A screen for phosphatidylinositol 3,4-bisphosphate and other 3-phosphoinositide effector proteins

  2010cites this paper
• The PH domain adaptor protein Bam32/DAPP1 functions in mast cells to restrain FcɛRI-induced calcium flux and granule release.

  2010cites this paper
• This information is current as Germinal Center Progression Protein Bam 32 / DAPP 1 Is Required for The Pleckstrin Homology Domain Adaptor

  2009cites this paper
• Phosphatidylinositol 3-kinase: a key regulator in adherens junction formation and function.

  2009cites this paper
• The Pleckstrin Homology Domain Adaptor Protein Bam32/DAPP1 Is Required for Germinal Center Progression

  2009influential citation
• Phosphoinositide 3‐kinase‐regulated adapters in lymphocyte activation

  2009cites this paper
• Cellular consequences of inositol depletion.

  2009cites this paper
• Regulation of B-lymphocyte activation by the PH domain adaptor protein Bam32/DAPP1.

  2007cites this paper
• Laminin-induced activation of Rac1 and JNKp46 is initiated by Src family kinases and mimics the effects of skeletal muscle contraction.

  2007cites this paper
• Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display

  2006cites this paper
• Role of the adaptor proteins Bam32, TAPP1 and TAPP2 in lymphocyte activation.

  2005cites this paper
• Modulation of the Cardiac Sodium Channel NaV1.5 by Fyn, a Src Family Tyrosine Kinase

  2005cites this paper
• The B Lymphocyte Adaptor Molecule of 32 Kilodaltons (Bam32) Regulates B Cell Antigen Receptor Internalization1

  2004influential citation
• Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event.

  2004cites this paper
• The Adaptor Protein Bam32 Regulates Rac1 Activation and Actin Remodeling through a Phosphorylation-dependent Mechanism*

  2004cites this paper
• Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates

  2004cites this paper
• Proximal B cell receptor signaling pathways

  2004cites this paper
• LL5beta is a phosphatidylinositol (3,4,5)-trisphosphate sensor that can bind the cytoskeletal adaptor, gamma-filamin.

  2003cites this paper
• LL5β Is a Phosphatidylinositol (3,4,5)-Trisphosphate Sensor That Can Bind the Cytoskeletal Adaptor, γ-Filamin* 210

  2003cites this paper
• CHAPTER 154 – Role of PDK1 in Activating AGC Protein Kinase

  2003cites this paper
• Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.

  2003cites this paper
• Ligand-independent trans-Activation of the Platelet-derived Growth Factor Receptor by Reactive Oxygen Species Requires Protein Kinase C-δ and c-Src*

  2002cites this paper
• Insulin Regulation of Insulin-like Growth Factor-binding Protein-1 Gene Expression Is Dependent on the Mammalian Target of Rapamycin, but Independent of Ribosomal S6 Kinase Activity*

  2002cites this paper
• Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo.

  2002cites this paper
• Hepatitis B Virus X Protein Activates the p38 Mitogen-Activated Protein Kinase Pathway in Dedifferentiated Hepatocytes

  2002cites this paper
• Evidence that the tandem-pleckstrin-homology-domain-containing protein TAPP1 interacts with Ptd(3,4)P2 and the multi-PDZ-domain-containing protein MUPP1 in vivo

  2002cites this paper
• Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture.

  2001cites this paper
• Src Family Kinases Mediate Receptor-stimulated, Phosphoinositide 3-Kinase-dependent, Tyrosine Phosphorylation of Dual Adaptor for Phosphotyrosine and 3-Phosphoinositides-1 in Endothelial and B Cell Lines*

  2001cites this paper
• Phosphoinositide 3-kinase signalling pathways.

  2001cites this paper
• Phosphoinositide-regulated kinases and phosphoinositide phosphatases.

  2001cites this paper
• Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

  2000cites this paper
• DAPP1 undergoes a PI 3-kinase-dependent cycle of plasma-membrane recruitment and endocytosis upon cell stimulation.

  2000influential citation