Comparison of Lipid Profiles in Normal Pregnancy and in Pre- Eclampsia: A Case Control Study

Objective: The objective of the study was to compare the changes in lipid profile in normal pregnancy and in preeclampsia. Study Design: A case control study. Method: In this case control study total 180 study subjects were evaluated, 90 normotensive pregnant woman as control group and 90 pre-eclamptic subjects as study group. Fasting venous blood samples were collected and serum levels of triglycerides (TG), Total cholesterol (TC), low density lipoprotein- cholesterol (LDL-C), and Very low density lipoprotein – Cholesterol (VLDL-C), High density lipoprotein cholesterol (HDL-C) were measured. Result: Results showed that in pre-eclamptic group serum triglyceride (212.75 ± 50.29 mg/dl) was increased significantly (p < 0.02) as compared to normotensive pregnant woman (185.60± 40.67 mg/dl). Other parameters TC, LDL-C, VLDL-C and HDL-C were not changed significantly. Conclusion: The findings of the present study are consistent with previous studies, suggesting increased level of serum triglyceride as an important factor in the pathological process of pre-eclampsia.

• Publication year

  2013

• Venue

  IOSR Journal of Dental and Medical Sciences

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.9790/0853-1145355
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Hypertensive Disorders in Pregnancy

  2019cited by this paper
• Hypertension and Renal Disease in Pregnancy

  2009cited by this paper
• European Journal of Obstetrics & Gynecology and Reproductive Biology. Editors' highlights.

  2009cited by this paper
• Brief overview of maternal triglycerides as a risk factor for pre‐eclampsia

  2006cited by this paper
• Biochemical markers and physiological parameters as indices for identifying patients at risk of developing pre-eclampsia.

  2005cited by this paper
• Maternal plasma lipid concentrations in early pregnancy and risk of preeclampsia.

  2004cited by this paper
• Plasma lipid and lipoprotein concentrations in pregnancy induced hypertension.

  2003cited by this paper
• Fasting plasma glucose and cholesterol levels in pregnant Nigerian women.

  2003cited by this paper
• Leptin, leptin resistance and endothelial dysfunction in pre-eclampsia.

  2002cited by this paper
• Lipoprotein (a) levels in normal pregnancy and in pregnancy complicated with pre-eclampsia.

  2000cited by this paper
• Small low-density lipoproteins and vascular cell adhesion molecule-1 are increased in association with hyperlipidemia in preeclampsia.

  1998cited by this paper
• Lipoprotein Subfraction Concentrations in Preeclampsia: Pathogenic Parallels to Atherosclerosis

  1997influential reference
• Dewhurst's textbook of obstetrics and gynaecology for postgraduates

  1995cited by this paper
• [Concentration of lipids and lipoproteins in serum of women with pregnancy induced hypertension].

  1995cited by this paper
• Maternal serum lipid profile in pregnancies complicated by hypertensive disorders

  1990cited by this paper
• Effects of estrogenic compounds on triglyceride kinetics.

  1975cited by this paper

• Frequency of Pregnancy Induced Hypertension in pregnant patients presenting in a tertiary care hospital and Comparison of Serum Lipid Profile in Normotensive and Hypertensive Pregnant Women

  2020cites this paper
• Pre–eclampsia and dyslipidaemia a case control study: an experience of tertiary healthcare centre in central India

  2018cites this paper
• STUDY OF LIPID PROFILE IN ECLAMPSIA

  2017cites this paper
• Evaluation of Serum Uric Acid and Lipid Profile in Pre-eclamptic Women: A Hospital Based Study

  2016cites this paper
• The effects of maternal serum lipid on maternal blood pressure and fetal birth weight: a prospective cohort study

  2015cites this paper
• Evaluation of maternal thyroid hormone status and atherogenic potency in pre eclampsia in Kolar district- a south west of India.

  2015cites this paper
• TO DETERMINE ASSOCIATION OF LIPID PROFILE, SERUM URIC ACID AND BODY MASS INDEX AS A MARKER FOR PREECLAMPSIA -

  2015cites this paper