Synthetic Approaches to Nuclease-Resistant, Nonnatural Dinucleotides of Anti-Hiv Integrase Interest

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Nucleosides, Nucleotides & Nucleic Acids

• Publication date

  2005-09-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1080/15257770500265703PMID 16438028
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inhibition of the strand transfer step of HIV-1 integrase by non-natural dinucleotides.

  2004cited by this paper
• Resistance towards exonucleases of dinucleotides with stereochemically altered internucleotide phosphate bonds.

  2004cited by this paper
• NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, 20(3), 197–211 (2001) AN IMPROVED SYNTHESIS OF THE DINUCLEOTIDES pdCpA AND pdCpdA

  2003cited by this paper
• Novel inhibitors of HIV integrase: the discovery of potential anti-HIV therapeutic agents.

  2003cited by this paper
• Structure activity of 3-aryl-1,3-diketo-containing compounds as HIV-1 integrase inhibitors.

  2002cited by this paper
• HIV integrase as a target for antiviral chemotherapy

  2002cited by this paper
• A New General Synthesis of Isomeric Nucleosides.

  2001cited by this paper
• Recognition and Inhibition of HIV Integrase by Novel Dinucleotides

  2000influential reference
• 4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells.

  2000cited by this paper
• Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells.

  2000cited by this paper
• HIV integrase structure and function.

  1999cited by this paper
• Integrating DNA: transposases and retroviral integrases.

  1999cited by this paper
• Self-complementary oligodeoxyribonucleotides incorporating L-related isodeoxynucleosides: synthesis, physical characterization, enzymology, and CD studies.

  1998cited by this paper
• HIV-1: fifteen proteins and an RNA.

  1998cited by this paper
• Probing interactions between viral DNA and human immunodeficiency virus type 1 integrase using dinucleotides.

  1997cited by this paper
• Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures.

  1996cited by this paper
• Nucleosides and nucleotides. 132. Synthesis and biological evaluations of ring-expanded oxetanocin analogues: Purine and pyrimidine analogues of 1,4-anhydro-2-deoxy-d-arabitol and 1,4-anhydro-2-deoxy-3-hydroxymethyl-d-arabitol

  1994cited by this paper
• Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases.

  1994cited by this paper
• Isodideoxynucleosides: A Conceptually New Class of Nucleoside Antiviral Agents.

  1993cited by this paper
• Specific binding of arginine to TAR RNA.

  1992influential reference
• Cyclic sulfates containing acid-sensitive groups and chemoselective hydrolysis of sulfate esters

  1989cited by this paper
• Novel, stable congeners of the antiretroviral compound 2',3'-dideoxyadenosine

  1989cited by this paper
• Oligonucleotide synthesis : a practical approach

  1984cited by this paper
• Reactions of relevance to the chemistry of aminoglycoside antibiotics. Part 7. Conversion of thiocarbonates into deoxy-sugars.

  1977cited by this paper
• The tert-Butyldimethylsilyl Group as a Protecting Group in Deoxynucleosides

  1973cited by this paper

• Nucleosides with Transposed Base or 4'-Hydroxymethyl Moieties and Their Corresponding Oligonucleotides.

  2015cites this paper
• Methodologies for the Synthesis of Isomeric Nucleosides and Nucleotides of Antiviral Significance

  2013cites this paper
• Enzymatic Recognition of 2′‐Modified Ribonucleoside 5′‐Triphosphates: Towards the Evolution of Versatile Aptamers

  2012cites this paper
• Nucleotide‐Based Inhibitors of HIV Integrase

  2011cites this paper
• A Rapid and Efficient Synthesis of D‐erythro‐Sphingosine from D‐ribo‐Phytosphingosine

  2011cites this paper
• Incorporation of 2′‐Deoxy‐2′‐isonucleoside 5′‐Triphosphates (iNTPs) into DNA by A‐ and B‐Family DNA Polymerases with Different Recognition Mechanisms

  2010cites this paper
• Diastereoselective addition of planar N-heterocycles to vinyl sulfone-modified carbohydrates: a new route to isonucleosides

  2008cites this paper
• Recent progress in the development of inhibitors of human immunodeficiency virus (HIV) integrase for the management of HIV infection.

  2008cites this paper
• HIV integrase inhibitors as therapeutic agents in AIDS

  2007cites this paper