Regulation of Multiple Stages of Hepadnavirus Replication by the Carboxyl-Terminal Domain of Viral Core Protein in trans

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Virology

• Publication date

  2014-12-24

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.03116-14PMID 25540387PMCID PMC4325754
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphoacceptors Threonine 162 and Serines 170 and 178 within the Carboxyl-Terminal RRRS/T Motif of the Hepatitis B Virus Core Protein Make Multiple Contributions to Hepatitis B Virus Replication

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• Maturation-Associated Destabilization of Hepatitis B Virus Nucleocapsid

  2013influential reference
• Hepatitis B virus reverse transcriptase: diverse functions as classical and emerging targets for antiviral intervention

  2013cited by this paper
• Cyclin-Dependent Kinase 2 Phosphorylates S/T-P Sites in the Hepadnavirus Core Protein C-Terminal Domain and Is Incorporated into Viral Capsids

  2012influential reference
• Secretion of Genome-Free Hepatitis B Virus – Single Strand Blocking Model for Virion Morphogenesis of Para-retrovirus

  2011cited by this paper
• Serine Phosphoacceptor Sites within the Core Protein of Hepatitis B Virus Contribute to Genome Replication Pleiotropically

  2011cited by this paper
• Phosphorylation State-Dependent Interactions of Hepadnavirus Core Protein with Host Factors

  2011influential reference
• Generation of Covalently Closed Circular DNA of Hepatitis B Viruses via Intracellular Recycling Is Regulated in a Virus Specific Manner

  2010cited by this paper
• Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles

  2010cited by this paper
• Nucleoporin 153 Arrests the Nuclear Import of Hepatitis B Virus Capsids in the Nuclear Basket

  2010cited by this paper
• Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation

  2007cited by this paper
• Formation of Hepatitis B Virus Covalently Closed Circular DNA: Removal of Genome-Linked Protein

  2007influential reference
• Deamination-Independent Inhibition of Hepatitis B Virus Reverse Transcription by APOBEC3G

  2007cited by this paper
• Regulation of Hepadnavirus Reverse Transcription by Dynamic Nucleocapsid Phosphorylation

  2006influential reference
• Reverse transcription-associated dephosphorylation of hepadnavirus nucleocapsids.

  2005influential reference
• Requirement of Heat Shock Protein 90 for Human Hepatitis B Virus Reverse Transcriptase Function

  2004cited by this paper
• Duck Hepatitis B Virus Virion Secretion Requires a Double-Stranded DNA Genome

  2003cited by this paper
• Conditional Replication of Duck Hepatitis B Virus in Hepatoma Cells

  2003cited by this paper
• Nuclear import of hepatitis B virus capsids and release of the viral genome

  2003cited by this paper
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  2002cited by this paper
• Identification of SRPK1 and SRPK2 as the Major Cellular Protein Kinases Phosphorylating Hepatitis B Virus Core Protein

  2002cited by this paper
• Signals for Bidirectional Nucleocytoplasmic Transport in the Duck Hepatitis B Virus Capsid Protein

  2001cited by this paper
• Core Protein Phosphorylation Modulates Pregenomic RNA Encapsidation to Different Extents in Human and Duck Hepatitis B Viruses

  2000cited by this paper
• Phosphorylation-dependent Binding of Hepatitis B Virus Core Particles to the Nuclear Pore Complex

  1999influential reference
• Roles of the three major phosphorylation sites of hepatitis B virus core protein in viral replication.

  1999cited by this paper
• The crystal structure of the human hepatitis B virus capsid.

  1999cited by this paper
• Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy

  1997cited by this paper
• Posttranscriptional regulation of hepatitis B virus replication by the precore protein

  1997cited by this paper
• Phosphorylation and nuclear localization of the hepatitis B virus core protein: significance of serine in the three repeated SPRRR motifs

  1995influential reference
• A single serine mutation on the nuclear localization signal of hepatitis B virus core protein abolishes the inhibition of nuclear transport by surface proteins.

  1995cited by this paper
• Effect of core protein phosphorylation by protein kinase C on encapsidation of RNA within core particles of hepatitis B virus

  1994cited by this paper
• Multiple functions of capsid protein phosphorylation in duck hepatitis B virus replication

  1994cited by this paper
• Phosphorylation of the duck hepatitis B virus capsid protein associated with conformational changes in the C terminus

  1994cited by this paper
• Construction of avian hepadnavirus variants with enhanced replication and cytopathicity in primary hepatocytes

  1994cited by this paper
• Rapid resolution of duck hepatitis B virus infections occurs after massive hepatocellular involvement

  1992cited by this paper
• Hepadnaviral assembly is initiated by polymerase binding to the encapsidation signal in the viral RNA genome.

  1992cited by this paper
• The arginine-rich domain of the hepatitis B virus core protein is required for pregenome encapsidation and productive viral positive-strand DNA synthesis but not for virus assembly

  1992cited by this paper
• Morphogenetic and regulatory effects of mutations in the envelope proteins of an avian hepadnavirus

  1991cited by this paper
• Hepatitis B virus core antigen has two nuclear localization sequences in the arginine-rich carboxyl terminus

  1991cited by this paper
• A domain of the hepadnavirus capsid protein is specifically required for DNA maturation and virus assembly

  1991cited by this paper
• Polymerase gene products of hepatitis B viruses are required for genomic RNA packaging as well as for reverse transcription

  1990cited by this paper
• In hepatocytes infected with duck hepatitis B virus, the template for viral RNA synthesis is amplified by an intracellular pathway.

  1990cited by this paper
• The arginine-rich domain of hepatitis B virus precore and core proteins contains a signal for nuclear transport

  1990cited by this paper
• Hepadnavirus envelope proteins regulate covalently closed circular DNA amplification

  1990cited by this paper
• Characterization of the major duck hepatitis B virus core particle protein

  1989cited by this paper
• The duck hepatitis B virus core protein contains a highly phosphorylated C terminus that is essential for replication but not for RNA packaging

  1989cited by this paper
• Formation of the pool of covalently closed circular viral DNA in hepadnavirus-infected cells.

  1986cited by this paper
• Replication of the genome of a hepatitis B--like virus by reverse transcription of an RNA intermediate.

  1982cited by this paper
• Protein Kinase Activity in Hepatitis B Virus

  1980cited by this paper
• Selective extraction of polyoma DNA from infected mouse cell cultures.

  1967cited by this paper

• From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair

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• SRPK2 Mediates HBV Core Protein Phosphorylation and Capsid Assembly via Docking Interaction

  2024cites this paper
• Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation

  2023cites this paper
• Inhibitory activities of Ranunculus japonicus Thunb. ethanol extract against hepatitis B virus

  2022cites this paper
• Antiviral activities of Polygonum perfoliatum L. extract and related phenolic acid constituents against hepatitis B virus

  2022cites this paper
• Conserved Lysine Residues of Hepatitis B Virus Core Protein Are Not Required for Covalently Closed Circular DNA Formation

  2022cites this paper
• Host cell-dependent late entry step as determinant of hepatitis B virus infection

  2022cites this paper
• Phosphoproteomics Unravel HBV Triggered Rewiring of Host Phosphosignaling Events

  2022cites this paper
• Region-Specific Hepatitis B Virus Genome Exposure from Nucleocapsid Modulated by Capsid Linker Sequence and Inhibitor: Implications for Uncoating

  2022cites this paper
• In vitro expression of precore proteins of hepatitis B virus subgenotype A1 is affected by HBcAg, and can affect HBsAg secretion

  2021cites this paper
• PP2A Phosphatase as an Emerging Viral Host Factor

  2021cites this paper
• Research progress in hepatitis B virus covalently closed circular DNA

  2021cites this paper
• Multiple roles of PP2A binding motif in hepatitis B virus core linker and PP2A in regulating core phosphorylation state and viral replication

  2021cites this paper
• Regulation of Hepatitis B Virus Replication by Cyclin Docking Motifs in Core Protein

  2021influential citation
• Hepatitis B Virus cccDNA: Formation, Regulation and Therapeutic Potential.

  2020cites this paper
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  2020cites this paper
• Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation

  2020cites this paper
• Intracellular Trafficking of HBV Particles

  2020cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Host-regulated Hepatitis B Virus Capsid Assembly in a Mammalian Cell-free System.

  2018cites this paper
• Virological Basis for the Cure of Chronic Hepatitis B.

  2018cites this paper
• Common and Distinct Capsid and Surface Protein Requirements for Secretion of Complete and Genome-Free Hepatitis B Virions

  2018cites this paper
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  2017influential citation
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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• Intracellular transport and egress of hepatitis B virus.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
• Viral DNA-Dependent Induction of Innate Immune Response to Hepatitis B Virus in Immortalized Mouse Hepatocytes

  2015cites this paper
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  2015cites this paper
• Core protein: A pleiotropic keystone in the HBV lifecycle.

  2015cites this paper
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  2015cites this paper