Changes in APP, PS1 and other factors related to Alzheimer’s disease pathophysiology after trimethyltin-induced brain lesion in the rat

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Neurotoxicity research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1080/1029842021000045471PMID 12709301
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cholinergic and dopaminergic alterations in the mouse central nervous system following acute trimethyltin exposure.

  2009cited by this paper
• Neuropathological stageing of Alzheimer-related changes

  2004cited by this paper
• Regional variations in nerve cell responses to trimethyltin intoxication in Mongolian gerbils and rats; further evidence for involvement of the Golgi apparatus

  2004cited by this paper
• Signal Transduction in Alzheimer’s Disease

  2002cited by this paper
• Going new places using an old MAP: tau, microtubules and human neurodegenerative disease.

  2001cited by this paper
• Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure.

  2001cited by this paper
• A Portrait of Alzheimer Secretases--New Features and Familiar Faces

  2001cited by this paper
• Early c-Fos Induction after Cerebral Ischemia: A Possible Neuroprotective Role

  2001cited by this paper
• Molecular and anatomical studies in Alzheimer's disease.

  2001cited by this paper
• Trimethyltin reduces ATP levels and MTT reduction in the LRM55 rat astrocytoma cell line.

  2000cited by this paper
• What the evolution of the amyloid protein precursor supergene family tells us about its function.

  2000cited by this paper
• Neuroinflammation and Alzheimer disease: clinical and therapeutic implications.

  2000cited by this paper
• Effect of dexamethasone on elevated cytokine mRNA levels in chemical‐induced hippocampal injury

  1999cited by this paper
• Translating cell biology into therapeutic advances in Alzheimer's disease

  1999cited by this paper
• Effects of mild traumatic brain injury on immunoreactivity for the inducible transcription factors c-Fos, c-Jun, JunB, and Krox-24 in cerebral regions associated with conditioned fear responding.

  1999cited by this paper
• Expression of AP-1 transcription factors in rat hippocampus and cerebellum after trimethyltin neurotoxicity.

  1999cited by this paper
• Expression of Presenilin 1 mRNA in Rat Peripheral Organs and Brain

  1999cited by this paper
• Microtechnology: Laying it on thick

  1999cited by this paper
• Caspase Dependent DNA Fragmentation Might Be Associated with Excitotoxicity in Alzheimer Disease

  1998cited by this paper
• Cellular localization and temporal elevation of tumor necrosis factor-alpha, interleukin-1 alpha, and transforming growth factor-beta 1 mRNA in hippocampal injury response induced by trimethyltin.

  1998cited by this paper
• Glial‐Neuronal Interactions in Alzheimer's Disease: The Potential Role of a ‘Cytokine Cycle’ in Disease Progression

  1998cited by this paper
• Alzheimer-associated presenilin-1 gene is induced in gerbil hippocampus after transient ischemia.

  1998cited by this paper
• Cellular Localization and Temporal Elevation of Tumor Necrosis Factor‐α, Interleukin‐1α, and Transforming Growth Factor‐β1 mRNA in Hippocampal Injury Response Induced by Trimethyltin

  1998cited by this paper
• The Role of Cytokines in the Neuropathology of Stroke and Neurotrauma

  1998cited by this paper
• Distribution of interleukin‐1‐immunoreactive microglia in cerebral cortical layers: implications for neuritic plaque formation in Alzheimer’s disease

  1998cited by this paper
• Trimethyltin exposure in the rat induces delayed changes in brain-derived neurotrophic factor, fos and heat shock protein 70.

  1997cited by this paper
• Altered expression of amyloid protein precursor mRNA in the rat hippocampus following trimethyltin intoxication: an in situ hybridization study.

  1997influential reference
• Hippocampal degeneration inducing impairment of learning in rats: model of dementia?

  1997cited by this paper
• Evidence for physiological down-regulation of brain oxidative phosphorylation in Alzheimer's disease.

  1996cited by this paper
• Regional and cellular presenilin 1 gene expression in human and rat tissues.

  1996cited by this paper
• Differential activation of microglia and astrocytes following trimethyl tin-induced neurodegeneration.

  1996cited by this paper
• Molecular cloning and expression of the rat homologue of presenilin-1.

  1996cited by this paper
• In situ hybridization analysis of presenilin 1 mRNA in Alzheimer disease and in lesioned rat brain.

  1996cited by this paper
• Microglial inter leukin‐1α expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution

  1995cited by this paper
• Trimethyltin increases interleukin (IL)-1 alpha, IL-6 and tumor necrosis factor alpha mRNA levels in rat hippocampus.

  1995cited by this paper
• Induction of interleukin-1 beta mRNA and enkephalin mRNA in the rat adrenal gland by lipopolysaccharides studied by in situ hybridization histochemistry.

  1995cited by this paper
• Time-course of trimethyltin effects on the monoaminergic systems of the rat brain.

  1995cited by this paper
• Trimethyltin increases interleukin (IL)-lα, IL-6 and tumor necrosis factor α mRNA levels in rat hippocampus

  1995cited by this paper
• Induction of lnterleukin-1β mRNA and Enkephalin mRNA in the Rat Adrenal Gland by Lipopolysaccharides Studied by in situ Hybridization Histochemistry (Part 1 of 2)

  1995cited by this paper
• Mitochondrial dysfunction and oxidative damage in neurodegenerative diseases

  1995cited by this paper
• Immunohistochemical evidence for apoptosis in Alzheimer's disease.

  1994cited by this paper
• The Earliest Signs of Alzheimer's Disease

  1994cited by this paper
• Changes in muscarinic (M1 and M2 subtypes) and phencyclidine receptor density in the rat brain following trimethyltin intoxication.

  1994cited by this paper
• Increased expression of c-fos mRNA and AP-1 transcription factors after cortical impact injury in rats.

  1994cited by this paper
• Trimethyltin Neurotoxicity in the Rat as an Analogous Model of Alzheimer’s Disease

  1994cited by this paper
• The effect of time following exposure to trimethyltin (TMT) on cholinergic muscarinic receptor binding in rat hippocampus.

  1994cited by this paper
• Trimethyltin-induced c-fos expression: adolescent vs neonatal rat hippocampus.

  1993cited by this paper
• Differential regional and cellular distribution of beta-amyloid precursor protein messenger RNAs containing and lacking the Kunitz protease inhibitor domain in the brain of human, rat and mouse.

  1993cited by this paper
• Sensitive mRNA detection using unfixed tissue: combined radioactive and non-radioactive in situ hybridization histochemistry

  1992cited by this paper
• Behavioural, biochemical and histological effects of trimethyltin (TMT) induced brain damage in the rat.

  1992cited by this paper
• Ubiquitin, PGP 9.5 and dense body formation in trimethyltin intoxication: differential neuronal responses to chemically induced cell damage

  1992cited by this paper
• Induction of Interleukin‐1β mRNA in Rat Brain After Transient Forebrain Ischemia

  1992cited by this paper
• Induction of interleukin-1 beta mRNA in rat brain after transient forebrain ischemia.

  1992cited by this paper
• Acute short-term memory loss from trimethyltin exposure.

  1991cited by this paper
• Triorganotins inhibit the mitochondrial inner membrane anion channel.

  1991cited by this paper
• Effects of kainic acid on messenger RNA levels of IL-1 beta, IL-6, TNF alpha and LIF in the rat brain.

  1991cited by this paper
• Methamphetamine-induced expression of interleukin-1 beta mRNA in the rat hypothalamus.

  1991cited by this paper
• Methamphetamine-induced expression of interleukin-1β mRNA in the rat hypothalamus

  1991cited by this paper
• Effects of kainic acid on messenger RNA levels of IL-1β, IL-6, TNFα and LIF in the rat brain

  1991cited by this paper
• A comparison of the psychopharmacological profiles of phencyclidine, ketamine and (+) SKF 10,047 in the trimethyltin rat model.

  1990cited by this paper
• Exposure to trimethyltin significantly enhances acetylcholinesterase staining in the rat dentate gyrus.

  1990cited by this paper
• Overview of depression and psychosis in Alzheimer's disease.

  1989cited by this paper
• Alkyltin inhibition of ATPase activities in tissue homogenates and subcellular fractions from adult and neonatal rats.

  1988cited by this paper
• Selective behavioural impairment after acute intoxication with trimethyltin (TMT) in rats.

  1988cited by this paper
• Brain injury induces c-fos protein(s) in nerve and glial-like cells in adult mammalian brain.

  1988cited by this paper
• Alzheimer's disease amyloidogenic glycoprotein: expression pattern in rat brain suggests a role in cell contact.

  1988cited by this paper
• The Progression of Personality Changes in Senile Dementia of the Alzheimer's Type

  1987cited by this paper
• Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro.

  1987cited by this paper
• Tin distribution in adult rat tissues after exposure to trimethyltin and triethyltin.

  1984cited by this paper
• A time-course study of trimethyltin induced neuropathology in rats.

  1983cited by this paper
• Trimethyltin, a selective limbic system neurotoxicant, impairs radial-arm maze performance.

  1982cited by this paper
• Trimethyltin, a selective limbic system neurotoxicant, impairs radial-arm maze performance.

  1982cited by this paper
• The trimethyltin syndrome in rats.

  1982cited by this paper
• Imparied maze performance in the rat caused by trimethyltin treatment: problem-solving deficits and perseveration.

  1982cited by this paper
• Neurotoxic effects of occupational exposure to organotins.

  1981cited by this paper
• Pathogenesis of trimethyltin neuronal toxicity. Ultrastructural and cytochemical observations.

  1981cited by this paper
• The behavioral and neuropathologic sequelae of intoxication by trimethyltin compounds in the rat.

  1979cited by this paper
• Trimethyltin poisoning · report of two cases

  1978cited by this paper
• Oxidative phosphorylation. Halide-dependent and halide-independent effects of triorganotin and trioganolead compounds on mitochondrial functions.

  1977cited by this paper
• Triorganotin Compounds as Ionophores and Inhibitors of Ion Translocating ATPases

  1976cited by this paper

• Effects of Continuous Theta Burst Stimulation on Behavior and NMDA Receptor Subunits in the Trimethyltin-Induced Alzheimer's-like Disease Model.

  2026cites this paper
• Beta-sitosterol mitigates cognitive deficit and hippocampal neurodegeneration in mice with trimethyltin-induced toxicity

  2024cites this paper
• The effect of Gallic acid on prenatal entorhinal cortex and CA1/CA3 hippocampal areas in trimethyltin intoxication rat

  2022cites this paper
• Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model

  2022cites this paper
• Trimethyltin Increases Intracellular Ca2+ Via L-Type Voltage-Gated Calcium Channels and Promotes Inflammatory Phenotype in Rat Astrocytes In Vitro

  2021cites this paper
• Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model

  2021cites this paper
• Trimethyltin as a Model to Explore Mechanisms of Selective Neuronal Death, Glial Reactivity, and Repair

  2021cites this paper
• Effects of Dizocilpine, Midazolam and Their Co-Application on the Trimethyltin (TMT)-Induced Rat Model of Cognitive Deficit

  2021cites this paper
• Enhanced neurogenesis is involved in neuroprotection provided by rottlerin against trimethyltin-induced delayed apoptotic neuronal damage.

  2020cites this paper
• Animal model for sporadic dementia of Alzheimer’s type (SDAT) using streptozotocin and lipopolysaccharide combinations in rats

  2020cites this paper
• The neuroprotective effect of ethanolic extract Ocimum sanctum Linn. in the regulation of neuronal density in hippocampus areas as a central autobiography memory on the rat model of Alzheimer's disease.

  2020cites this paper
• Activation of pro-apoptotic cells, reactive astrogliosis and hyperphosphorylation of tau protein in trimethyltin-induced hippocampal injury in rats

  2020cites this paper
• Trimethyltin (TMT) Reduces Testosterone Production in Adult Leydig Cells in Rats

  2019cites this paper
• The neuroprotective effects of an ethanolic turmeric (Curcuma longa L.) extract against trimethyltin-induced oxidative stress in rats

  2019cites this paper
• Autophagy is Activated In Vivo during Trimethyltin-Induced Apoptotic Neurodegeneration: A Study in the Rat Hippocampus

  2019cites this paper
• Mouse Induced Pluripotent Stem Cells-Derived Alzheimer's Disease Cerebral Organoid Culture and Neural Differentiation Disorders.

  2019cites this paper
• Effect of Gotu Kola (Centella asiatica) Extract Toward Expression of Caspase 3 of Hippocampus Pyramidal Cells on Dementia Model Rats Induced by Trimethyltin.

  2019cites this paper
• Erucamide from Radish Leaves Has an Inhibitory Effect Against Acetylcholinesterase and Prevents Memory Deficit Induced by Trimethyltin

  2018cites this paper
• Treatment with Mountain-Cultivated Ginseng Alleviates Trimethyltin-Induced Cognitive Impairments in Mice via IL-6-Dependent JAK2/STAT3/ERK Signaling

  2017cites this paper
• In vivo magnetic resonance approach to trimethyltin induced neurodegeneration in rats.

  2017cites this paper
• Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in Trimethyltin‐induced neurodegeneration rat model

  2017cites this paper
• Gambaran Histopatologi Otak Tikus Akibat Injeksi Trimetyltin sebagai Model Penyakit Alzheimer

  2017cites this paper
• Trimethyltin-induced cochlear degeneration in rat

  2016cites this paper
• Enhanced expression of immediate-early genes in mouse hippocampus after trimethyltin treatment.

  2016cites this paper
• Progressive increase of lysosomal enzyme activities in hippocampus associated with reduction of population spike in a rat model of neurodegeneration.

  2016cites this paper
• Histopathological Analysis from Gallic Acid Administration on Hippocampal Cell Density, Depression, and Anxiety Related Behaviors in A Trimethyltin Intoxication Model

  2016cites this paper
• Trimethyltin-induced hippocampal neurodegeneration: A mechanism-based review.

  2016cites this paper
• Trimethyltin can induce cell death in the entorhinal cortex of rat brain: a histological architecture and neuronal density evaluation of the neuroprotective role of lithium chloride

  2015cites this paper
• Trimethyltin-Induced Microglial Activation via NADPH Oxidase and MAPKs Pathway in BV-2 Microglial Cells

  2015cites this paper
• Increased expression of Aquaporin 4 in the rat hippocampus and cortex during trimethyltin-induced neurodegeneration.

  2014cites this paper
• Pyridoindole antioxidant-induced preservation of rat hippocampal pyramidal cell number linked with reduction of oxidative stress yet without influence on cognitive deterioration in Alzheimer-like neurodegeneration.

  2014cites this paper
• Gene Expression Profiling as a Tool to Investigate the Molecular Machinery Activated during Hippocampal Neurodegeneration Induced by Trimethyltin (TMT) Administration

  2013cites this paper
• Neuroprotective Strategies in Hippocampal Neurodegeneration Induced by the Neurotoxicant Trimethyltin

  2012cites this paper
• Early and late stage of neurodegeneration induced by trimethyltin in hippocampus and cortex of male Wistar rats.

  2012cites this paper
• The involvement of P2X₁ receptor in pyramidal cell degeneration in the rat hippocampus after trimethyltin administration.

  2011cites this paper
• Trimethyltin-induced hippocampal degeneration as a tool to investigate neurodegenerative processes.

  2011cites this paper
• Novel mechanisms and approaches in the study of neurodegeneration and neuroprotection. A review

  2009cites this paper
• Introduction : the wide occurrence of TMT and its relevance to environmental health

  2009cites this paper
• The vitamin-E analog trolox and the NMDA antagonist MK-801 protect pyramidal neurons in hippocampal slice cultures from IL-1β-induced neurodegeneration

  2009cites this paper
• Neurotoxins and neurotoxic species implicated in neurodegeneration

  2009cites this paper
• Methylated tin toxicity a reappraisal using rodents models.

  2009cites this paper
• Trimethyltin-evoked apoptosis of murine hippocampal granule neurons is accompanied by the expression of interleukin-1beta and interleukin-1 receptor antagonist in cells of ameboid phenotype, the majority of which are NG2-positive.

  2008cites this paper
• Dysregulation of intracellular calcium homeostasis is responsible for neuronal death in an experimental model of selective hippocampal degeneration induced by trimethyltin

  2008cites this paper
• Trimethyltin-induced microglial activation and its mechanisms in BV-2 cells

  2008cites this paper
• Recent studies on the trimethyltin actions in central nervous systems.

  2007cites this paper
• Trimethyltin-induced differential expression of PAR subtypes in reactive astrocytes of the rat hippocampus.

  2004cites this paper